paceroneAmiodarone-Oral

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pacerone Amiodarone-Oral Pacerone (amiodarone) 200 mg

pacerone Amiodarone-Oral Pacerone (amiodarone) 400 mg

pacerone Amiodarone-Oral Pacerone (amiodarone) 100 mg

Prescription Drug Information, Side Effects & Interactions for pacerone Amiodarone-Oral

Uses
Pacerone is used to treat irregular heart rhythms (arrhythmias) and to maintain a normal heart rate.

Storage

Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture.
Do not store in the bathroom.
Keep all medicines away from children and pets.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately.
Symptoms of overdose may include weakness, severe dizziness, unusually slow heartbeat, or fainting.

pacerone Amiodarone-Oral Pacerone (amiodarone) 400 mg

How To Use

Take Pacerone by mouth.
It is best taken with food.
However, it is more important to take amiodarone consistently, with regard to meals.
Ask your pharmacist for additional information.
Pacerone works best when there is a constant level of Pacerone in your body.
To do this, take each dose exactly as prescribed at evenly spaced intervals throughout the day and night.
Try to take each dose at the same time each day.
Do not stop taking Pacerone or change the dose without first consulting your doctor.
Some conditions may become worse when Pacerone is suddenly stopped or when more drug is taken than prescribed.

Side Effects

Also see the Warning section.
Constipation, loss of appetite, bitter taste in mouth, nausea, vomiting, dizziness, trouble sleeping, headache, flushing of the face, or decreased sexual interest may occur as your body adjusts to the medication.
If any of these effects persist or worsen, notify your doctor promptly.
Pacerone, when used in combination with simvastatin, may infrequently cause muscle damage (which can rarely lead to a very serious condition called rhabdomyolysis).
Tell your doctor immediately if you develop: muscle pain/tenderness/weakness (especially with fever or unusual tiredness).
Tell your doctor immediately if any of these unlikely but serious side effects occur: coldness, sweating, unexplained weight change, enlarged thyroid gland, nervousness, uncontrolled shaking/tremor, sluggishness, loss of coordination, tingling or numbness of the hands or feet, swelling of the hands or feet, irregular pulse, vision changes (e.g., seeing halos, blurred vision, loss of vision - See Warnings), easy bruising/bleeding, persistent sore throat.
Pacerone may cause skin reactions similar to a serious sunburn.
Infrequently with long-term amiodarone treatment, you may develop blue-gray discoloring of the skin, particularly of the face and hands.
This effect is not harmful and usually reverses, sometimes incompletely, after Pacerone is stopped.
Avoiding prolonged sun exposure may help to prevent this effect.
See also Precautions.
In the unlikely event you have an allergic reaction to Pacerone, seek immediate medical attention.
Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing.
If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Pacerone should not be used if you have certain medical conditions.
Before using Pacerone, consult your doctor or pharmacist if you have: certain types of irregular heartbeats or heart rhythms (e.g., severe sinus node dysfunction resulting in marked sinus bradycardia, second or third degree atrioventricular block, bradycardia with associated syncope except when a pacemaker is used).
Before using Pacerone, tell your doctor or pharmacist your medical history, especially of: liver disease, heart problems (e.g., congestive heart failure, low blood pressure), lung diseases, thyroid problems, upcoming major surgery, electrolyte problems such as low potassium or low magnesium, any allergies.
Pacerone may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery.
Limit alcoholic beverages.
Pacerone may make you more sensitive to the sun.
Avoid prolonged sun exposure, tanning booths or sunlamps.
Use a sunscreen and wear protective clothing when outdoors.
Pacerone is not recommended for use during pregnancy due to the potential for fetal harm.
Consult your doctor for more details.
Amiodarone passes into breast milk.
Breast-feeding is not recommended while using Pacerone.

Missed Dose

If you miss a dose, use it as soon as you remember.
If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
Do not double the dose to catch up.

Drug Interactions

Pacerone should not be used with the following medications because very serious interactions may occur: agalsidase beta, dofetilide, certain HIV protease inhibitors (nelfinavir, ritonavir), quinupristin/dalfopristin.
If you are currently using any of these medications, tell your doctor or pharmacist before starting amiodarone.
Other drugs besides amiodarone which may affect the heart rhythm (QTc prolongation in the EKG) include flecainide, disopyramide, pimozide, quinidine, sotalol, procainamide, and sparfloxacin among others.
QTc prolongation can infrequently result in serious, rarely fatal, irregular heartbeats.
Consult your doctor or pharmacist for details.
Ask for instructions about whether you need to stop any other QTc-prolonging drugs you may be using in order to minimize the risk of this effect.
Before using Pacerone, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: blood thinners (e.g., warfarin), cimetidine, cyclosporine, digoxin, fentanyl, local and general anesthesia, heart medications (e.g., diltiazem, verapamil, beta-blockers such as propranolol), other HIV protease inhibitors (e.g., amprenavir, indinavir), methotrexate, phenytoin, rifampin, statins (e.g., lovastatin, simvastatin), St.
John s wort.
Avoid eating grapefruit or drinking grapefruit juice while being treated with Pacerone unless your doctor instructs you otherwise.
Do not start or stop any medicine without doctor or pharmacist approval.