avandametRosiglitazone/metformin

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avandamet Rosiglitazone/metformin - Oral Avandamet (metformin/rosiglitazone)

avandamet Rosiglitazone/metformin - Oral GSK AVANDAMET（梵蒂美）

Prescription Drug Information, Side Effects & Interactions for avandamet Rosiglitazone/metformin - Oral

Uses
This combination medication is used along with a diet and exercise program to control high blood sugar in diabetic patients. Avandamet works by helping to restore your body s proper response to the insulin you naturally produce. Controlling high blood sugar helps prevent heart disease, strokes, kidney disease, blindness and circulation problems, as well as sexual function problems (impotence). Use of Avandamet is not recommended with insulin therapy.

Storage

Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture.
Brief storage from 59 to 86 degrees F (15 to 30 degrees C) is permitted.
Do not store in the bathroom.
Keep all medicines away from children and pets.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately.
Symptoms of overdose may include: rapid or trouble breathing, severe drowsiness, slow or irregular heartbeat.

avandamet Rosiglitazone/metformin - Oral GSK AVANDAMET（梵蒂美）

How To Use

Avandamet is best taken with meals.
Use Avandamet regularly in order to get the most benefit from it.
To help you remember, use it at the same time(s) each day.
Dosage is based on your medical condition and response to therapy.

Side Effects

Also see Warnings.
Nausea, stomach upset, diarrhea or metallic taste may occur initially as your body adjusts to the medication.
If stomach symptoms recur later (after you are on the same dose for several days or more), tell your doctor immediately.
A late recurrence of stomach symptoms may be due to lactic acidosis.
Headache, back pain, joint pain, weight gain, cough or fever may also occur.
If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Tell your doctor immediately if any of these unlikely but serious side effects occur: swelling of the hands or feet (edema), unusual tiredness or weakness, sudden weight gain, trouble breathing.
Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: vomiting, stomach pain, yellowing eyes or skin, dark urine.
Avandamet usually does not cause low blood sugar (hypoglycemia), but this effect may occur if you do not consume enough calories (from food, juices, fruit, etc.).
The symptoms include chills, cold sweat, dizziness, drowsiness, shaking, rapid heart rate, weakness, headache, fainting, tingling of the hands or feet, or hunger.
It is a good habit to carry glucose tablets or gel to treat low blood sugar.
If you are in a situation where you don t have these reliable forms of glucose, eat a quick source of sugar such as table sugar, honey, or candy, or drink a glass of orange juice or non-diet soda to quickly raise your blood sugar level.
Tell your doctor immediately about the reaction.
To help prevent hypoglycemia, eat meals on a regular schedule and do not skip meals.
Symptoms of high blood sugar (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, or fruity breath odor.
If these symptoms occur, tell your doctor immediately.
Your medication dosage may need to be increased.
An allergic reaction to Avandamet is unlikely, but seek immediate medical attention if it occurs.
Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing.
If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Avandamet should not be used if you have certain medical conditions.
Before using Avandamet, consult your doctor or pharmacist if you have: kidney disease, liver disease, conditions that may cause a low oxygen blood level or poor circulation (e.g., severe congestive heart failure, recent heart attack, recent stroke), lack of body fluids (dehydration), serious infection, metabolic acidosis (e.g., diabetic ketoacidosis), Type I diabetes (insulin-dependent diabetes).
Before using Avandamet, tell your doctor or pharmacist your medical history, especially of: severe breathing problems (e.g., obstructive lung disease, severe asthma), blood problems (e.g., anemia, vitamin B-12 deficiency), swelling (edema), fertility problems (e.g., ovulation problems), high cholesterol, scheduled upcoming surgery, alcohol use, any allergies.
Limit alcohol while using Avandamet.
During times of stress, such as fever, infection, injury or surgery, it may be more difficult to control your blood sugar.
Consult your doctor, as a change in your medication may be required.
Avandamet can cause changes in the menstrual cycle (promote ovulation) in women with certain fertility problems, increasing the risk of becoming pregnant.
Consult your doctor or pharmacist about the use of reliable birth control while using Avandamet.
Caution is advised when using Avandamet in the elderly because they may be more sensitive to the effects of Avandamet.
Avandamet should be used only when clearly needed during pregnancy.
Discuss the risks and benefits with your doctor.
It is not known whether Avandamet passes into breast milk.
Breast-feeding is not recommended while using Avandamet.

Missed Dose

If you miss a dose, use it as soon as you remember.
If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
Do not double the dose to catch up.

Drug Interactions

Avandamet should not be used with the following medications because very serious interactions may occur: insulin.
If you are currently using insulin, tell your doctor or pharmacist before starting rosiglitazone/metformin.
Before using Avandamet, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: other diabetes drugs (e.g., glyburide, acarbose), beta-blockers (e.g., propranolol), water pills (diuretics such as hydrochlorothiazide, furosemide), cimetidine, birth control pills, estrogens, corticosteroids (e.g., prednisone), niacin, phenytoin, decongestants, calcium channel blockers (e.g., nifedipine), phenothiazines (e.g., chlorpromazine), isoniazid, thyroid drugs, fenugreek, ginseng.
If you are scheduled to undergo any x-ray or scanning procedure using injectable iodinated contrast material, be sure to inform your doctor that you are taking Avandamet.
You will need to temporarily stop Avandamet around the time of your procedure.
Consult your doctor for further instructions.
Do not start or stop any medicine without doctor or pharmacist approval.