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Health Forum    Infectious Diseases
Health Discussion Forum

 Stomach Virus???????????????
I am a bit paranoid when it comes to germs. I have not been sick with one since 2006 and I want to keep it that way. I seem to not be getting sick alot even though I come in contact with sick people ...


 whats wrong with me?!!!!?
i have::

the sweats,fatigue,body aches,no fever,runny nose?

the flu? im so confused!...


 Is it illegal to refrain from telling students if you have tuberculosis?
Ok well this student was diagnosed with tuberculosis at my high school and I want to know if it's illegal for the principal and others to not let the student body know who the student is? I mean ...


 Will I get shingles or chicken pox?
Ok, I got chickenpox when I was 5 years old. I am now 13. Now, my brother has got the chickenpox even after being imunised. Can/will I get shingles or chickenpox or am I safe?...


 how many people died from plague?
...


 Food Poisoning Maybe?
i accidently ate undercooked pork (and my friend) whats the risk and what should i do? Processed sausage. Symptoms?...


 throat is a liddle tinggly??
i jus eat sum shrimp and some spiach rolls and then i had sum wata now my throat is alll tinggly and stuf.
whats giong on ...


 Cold remedies at the first signs of a developing cold?
Everytime I'm gonna get sick, I always get a really sore throat. I'll go to bed, and when I get up I'll be sick. Right now is such a time. Is there anything I can take before I go to ...


 Can a person carry and/or spread measles if they've been vaccinated?
I know he can't get measles himself, but if he was exposed to a person who was later confirmed to have measles, can he still carry and spread it?...


 What would you like to know about swine flu?
I figure since it has to be done in question form that will do. First off let me say unless you have a heart condition, diabetes,asthma or some other serious health problem you don't need to ...


 why do children needs vitamin A?and what are the signs and symptoms of vitamiin a deficiencies?
...


 under which conditions does malaria flourish?
...


 How does one treat fungal infections of the nails?
My friend has a fungal infection on one of his toenails, and he asked me how (if) they can be treated. Unfortunately I do not know (I never had these myself). Typical symptoms include but are not ...


 Is vacinations bad for babies?
...


 When I was little i got vacinated for Chicken Pox?
I have never got them in my life but there is a case of them at my school. Is there any possibility even a 1% chance i could still get them even though i have been vaccinated....


 any way I can get strep?
I already have a cold that begun Friday with a sore throat and is there any way I can give myself strep throat? Or get it? Please help and don't judge me, I have a ...


 What is in the MMR vaccine?
What is inside it like e.g. water lol i mean like what is inside the actuall injection?
im doing a case study also if you have anything interesting on about it like any experience email me or ...


 Has anyone ever had a breast abscess??? ONLY ANSWER IF YOU'VE HAD ONE!?
I have been breastfeeding for 4 months and I think I have an abscess. I had a yeast infection in my breast followed by a fever. My breast got hard on the left side, and I couldn't pump. Nothing ...


 How can help my friend?She is having AIDS.Can one buy AIDS drugs?
Can one buy AIDS drugs?...


 What is E coil? I'm Kinda Confused.?
...



menos1982
which antibiotics can pass BBB ( blood brain barrier ) ??? please i want accurate answer?
i m asking about antibiotics can cross BBB to treat meningitis
                      









Tech
Rating
Cefotaxime, ceftizoxime, ceftriaxone, cefepime, vancomycin, metronidazole, sulfas and erythromycin are some that quickly come to mind.

The penicillins and other early beta-lactam based antibiotics (methcillin, etc) also cross the blood brain barrier but in a limited fashion.

The BBB can be chemically or physically breached and then addition therapies implemented, but this is fairly rare.

HTH


Josh C
Rating
In meningitis the BBB is often damaged due to the infection and antibiotics penetrate more readily than they would in a non-infected person.

In meningitis a third or fourth generation cephalosporin is the usual treatment.


Anne2
Rating
Amoxicillin
Grepafloxacin
minocycline
levofloxacin
sparfloxacin
cfloxacin
fifampin
metronidazole
cotrimoxazole
penicillin passes the blood brain barrier in a limited fashion.
Is this Bacterial Meningitis, they tend to be the most difficult to treat, And it looks like Ceftriaxone is the most preferred one. Hope you are good with scanning the electron microscope. JAMA has an excellent article on this if you have
Journal capabilities. With use of Ceftriaxone, patients have to be carefully monitored. The trouble with most antibiotics is
they have larger molecules that cannot pass the BBB.


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