Vagifem is a female hormone and is usually given to women who no longer produce the proper amount. It is used to reduce menopause symptoms (e.g., vaginal dryness).
- Store at room temperature about 77 degrees F (25 degrees C) away from light and moisture.
- Brief storage between 59 to 86 degrees F (15 to 30 degrees C) is permitted.
- Do not store in the bathroom.
- Keep all medicines away from children and pets.
- If overdose is suspected, contact your local poison control center or emergency room immediately.
- Vagifem may be harmful if swallowed.
- Symptoms of overdose may include severe nausea/vomiting or excessive vaginal bleeding.
Directions for use of VAGIFEM :
VAGIFEM 25 MCG 15 VAGİNAL TABLET
- Follow the instructions and dosing schedule carefully.
- Insert the applicator into the vagina as directed and push the plunger to release the medication.
- Insert one tablet vaginally once daily for the first two weeks and then one tablet twice a week, or as directed by your doctor.
- It is best to schedule each dose about the same time of the day.
- Dizziness, lightheadedness, headache, stomach upset, bloating, nausea, weight changes, increased/decreased interest in sex, and breast tenderness may occur.
- If any of these effects persist or worsen, notify your doctor promptly.
- Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (e.g., severe depression, memory loss), calf pain/swelling, sudden severe headache, chest pain, trouble breathing, one-sided weakness, slurred speech, vision changes (e.g., change in contact lens fit, loss of vision), breast lumps, swelling of hands or feet, changes in vaginal bleeding (e.g., spotting, breakthrough bleeding or prolonged bleeding), unusual vaginal discharge/itching/odor, yellowing of the eyes or skin.
- An allergic reaction to Vagifem is unlikely, but seek immediate medical attention if it occurs.
- Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing.
- If you notice other effects not listed above, contact your doctor or pharmacist.
- Vagifem should not be used if you have certain medical conditions.
- Before using Vagifem, consult your doctor or pharmacist if you have: undiagnosed abnormal vaginal bleeding, certain cancers (e.g., breast cancer, especially non-metastatic type), blood clots, active/recent stroke or heart attack.
- Before using Vagifem, tell your doctor or pharmacist your medical history, especially of: family medical history (e.g., especially breast lumps and cancer), asthma, diabetes, seizures, migraine headaches, liver disease, heart disease (e.g., high blood pressure, heart attacks, congestive heart failure), kidney disease, low thyroid hormone (hypothyroidism), abnormal calcium level in the blood, depression, high blood pressure during pregnancy (toxemia), yellowing of eyes and skin (cholestatic jaundice) during pregnancy or with past estrogen use, womb problems (e.g., uterine fibroids, endometriosis), cholesterol or lipid problems, gallbladder disease, excessive weight gain, certain blood disorder (porphyria), any allergies.
- If you will be having surgery or will be confined to a chair or bed for a long period of time (e.g., a long plane flight), notify your doctor beforehand.
- Special precautions may need to be taken in these circumstances while you are taking Vagifem.
- Vagifem may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery.
- Limit alcoholic beverages.
- Vagifem may cause a patchy darkening of the skin on the face (melasma).
- Sunlight may intensify this darkening and you may need to avoid prolonged sun exposure and sunlamps.
- Consult your doctor regarding use of sunscreens and protective clothing.
- Cigarette smoking can increase the chance of blood clots while taking Vagifem (especially in women over the age of 35).
- Vagifem must not be used during pregnancy.
- If you become pregnant or think you may be pregnant, inform your doctor immediately.
- It is unknown if Vagifem passes into breast milk.
- Estrogens may have undesirable effects on a nursing infant.
- Therefore, breast-feeding while using Vagifem is not recommended.
- If you miss a dose, use it as soon as you remember.
- If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
- Do not double the dose to catch up.
- Before using Vagifem, tell your doctor or pharmacist of all prescription and nonprescription drugs you may use, especially of: other vaginal products.
- This product can affect the results of certain lab tests.
- Make sure laboratory personnel and your doctors know you use Vagifem.
- Do not start or stop any medicine without doctor or pharmacist approval.