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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

ultiva Uses Remifentanil is a pain medication used before and/or during surgery or other procedures requiring anesthesia. Ultiva may also be used for pain control after surgery under close supervision of a doctor or other medical (pain) specialist. Storage Store the vials between 36 and 77 degrees F (2 and 25 degrees C) away from light and moisture. Do not freeze. After mixing and dilution in correct IV fluids (consult your pharmacist for details), Ultiva is stable at room temperature for 4 hours. Discard any unused liquid. Overdose If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include trouble breathing, seizures, severe dizziness, or fast heartbeat. How To Use Ultiva is injected into a vein (slow IV injection or continuous infusion) by medical professionals specifically trained in the use of anesthetic drugs. Remifentanil should be used only in a hospital or clinical setting equipped with appropriate monitoring and life-support equipment. The dosage is based on the patient s medical condition and response to the medication. This product contains glycine and is not intended for epidural or intrathecal injection. Use Ultiva exactly as prescribed. Do not increase your dose, use it more frequently, or use it for a longer period of time than prescribed because Ultiva can be habit-forming. Also, if used for an extended period of time, do not suddenly stop using Ultiva without your doctor s approval. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist. Learn all mixing, dilution, and administration/usage instructions in the product package and ask your doctor or pharmacist if you are unclear about any of the information. Side Effects Dizziness, drowsiness, nausea, vomiting, shivering, or headache may occur. If any of these effects persist or worsen, contact your doctor or pharmacist promptly. Tell your doctor immediately if any of these serious side effects occur: slow or irregular heartbeat, fever, muscle or chest tightness, trouble breathing, seizures. An allergic reaction to Ultiva is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist. Precautions Tell your doctor your medical history, especially of: head injury, lung disease (e.g., asthma, emphysema), any allergies you may have (especially to codeine or fentanyl). Ultiva may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery until the dizziness or drowsiness caused by the anesthesia or Ultiva is no longer present. Avoid alcoholic beverages because they can intensify the dizziness or drowsiness effects of Ultiva. Caution is advised when using Ultiva in the elderly because they may be more sensitive to the effects of Ultiva. Caution is advised when using Ultiva in patients who are very overweight. Ultiva should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if Ultiva passes into breast milk. Consult your doctor before breast-feeding. Missed Dose Not applicable. Drug Interactions Tell your doctor or pharmacist of all prescription and nonprescription drugs you may use, especially of: MAO inhibitors used currently or stopped within the last 2 weeks (e.g., furazolidone, linezolid, moclobemide, phenelzine, procarbazine, selegiline). Tell your doctor if you take any drowsiness-causing medication, such as: drugs for sleep, sedatives, tranquilizers, anti-anxiety drugs (e.g., diazepam), narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., phenothiazines or tricyclics), anti- seizure drugs (e.g., carbamazepine), muscle relaxants, antihistamines that cause drowsiness (e.g., diphenhydramine). Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products. Do not start or stop any medicine without doctor or pharmacist approval.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.