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Bexarotene is used to treat a certain type of cancer affecting the skin, certain types of blood cells (lymphocytes), and lymph nodes (cutaneous T-cell lymphoma or CTCL).
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| Overview |
Photos |
How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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targretin
Uses
Bexarotene is used to treat a certain type of cancer affecting the skin, certain types of blood cells (lymphocytes), and lymph nodes (cutaneous T-cell lymphoma or CTCL).
Storage
- Store at room temperature between 36 and 86 degrees F (2 to 30 degrees C) away from light and moisture.
Overdose
- If overdose is suspected, contact your local poison control center or emergency room immediately.
Photos
TARGRETIN |
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Targretin (bexarotene) 75 mg |
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How To Use
- Take Targretin by mouth, usually once daily with a meal; or take as directed by your doctor.
- The dosage is based on your medical condition and response to therapy.
- It may take up to several months of continued use to see a response to treatment.
- Your dosage may need to be adjusted by your physician during this time.
Side Effects
- Headache, rash, nausea, vomiting, dry skin, diarrhea, or trouble sleeping may occur.
- If any of these effects persist or worsen, notify your doctor.
- Tell your doctor immediately if any of these serious side effects occur: unusual fatigue, stomach pain, swelling of the hands or feet, muscle pain/stiffness/cramps, unusually slow heartbeat.
- Tell your doctor immediately if any of these unlikely but serious side effects occur: yellowing eyes and skin, dark urine, vision changes, unusual weight loss.
- Targretin can lower the body s ability to fight an infection.
- Notify your doctor promptly if you develop any signs of an infection such as fever, chills, or persistent sore throat.
- If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Tell your doctor your medical history, especially of: heart disease, high cholesterol or triglyceride levels, pancreatitis, diabetes, kidney problems, liver problems, thyroid problems (e.g., hypothyroidism), cataracts, allergies.
- Targretin may make you more sensitive to the sun.
- Avoid prolonged sun exposure, use a sunscreen, and wear protective clothing when outdoors.
- Because Targretin can lower your body s ability to fight an infection, do not touch your eyes or the inside of your nose without first washing your hands.
- Do not have immunizations/vaccinations without the consent of your doctor and avoid contact with people who have recently received oral polio vaccine.
- Targretin must not be used during pregnancy.
- If you become pregnant or think you may be pregnant, inform your doctor immediately.
- Two effective forms of birth control must be used for 1 month before starting Targretin, during the use of Targretin, and for 1 month after stopping Targretin.
- It is not known if Targretin passes into breast milk.
- Due to the potential risk to the infant, breast-feeding while using Targretin is not recommended.
- Consult your doctor before breast- feeding.
- It is recommended men use condoms during sexual activity while on Targretin and for 1 month after the last dose.
Missed Dose
- If you miss a dose, use it as soon as you remember.
- If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
- Do not double the dose to catch up.
Drug Interactions
- Targretin is not recommended for use with gemfibrozil.
- If you are taking gemfibrozil, your treatment may be changed to a different cholesterol/lipid-lowering drug.
- Ask your doctor or pharmacist for more details.
- Tell your doctor of all prescription and nonprescription medication you may use, especially of: macrolide antibiotics (e.g., clarithromycin, erythromycin), cimetidine, azole antifungals (e.g., itraconazole, ketoconazole), nefazodone, phenytoin, phenobarbital, rifampin.
- Do not eat grapefruit or drink grapefruit juice unless your doctor instructs you otherwise.
- Targretin can affect the results of certain lab tests.
- Make sure laboratory personnel and your doctors know you use Targretin.
- Do not start or stop any medicine without doctor or pharmacist approval.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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