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Rifadin Iv is used in the treatment of tuberculosis or other infections when the oral form cannot be taken. Use of only rifampin and pyrazinamide as a two-drug, two-month therapy to treat tuberculosis (specifically latent TB infection) is no longer recommended. Infrequently, serious (sometimes fatal) liver disease has occurred with the use of these two drugs alone. Several other effective alternative treatments can be used to treat latent tuberculosis (e.g., isoniazid for 9 months). Use of rifampin and pyrazinamide as part of a multi-drug (3 or more drugs) treatment plan for tuberculosis is still acceptable. Consult your doctor or pharmacist for more details.
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Rifampin
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| Overview |
Photos |
How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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rifadin Iv
Rifampin
Uses
Rifadin Iv is used in the treatment of tuberculosis or other infections when the oral form cannot be taken. Use of only rifampin and pyrazinamide as a two-drug, two-month therapy to treat tuberculosis (specifically latent TB infection) is no longer recommended. Infrequently, serious (sometimes fatal) liver disease has occurred with the use of these two drugs alone. Several other effective alternative treatments can be used to treat latent tuberculosis (e.g., isoniazid for 9 months). Use of rifampin and pyrazinamide as part of a multi-drug (3 or more drugs) treatment plan for tuberculosis is still acceptable. Consult your doctor or pharmacist for more details.
Storage
- The undiluted vials of Rifadin Iv may be stored at room temperature as directed.
- If diluted in 10 ml, use within 24 hours.
- If diluted in 100 ml or 500 ml use within 4 hours.
- Check the expiration date on the label and properly discard of any unused medication after that date.
Overdose
- If overdose is suspected, contact your local poison control center or emergency room immediately.
- Symptoms of overdose may include swelling of face or around eyes, itching over the entire body, orange or red discoloration of skin or eyes, nausea, vomiting, drowsiness, and loss of consciousness.
Photos
Rifadin IV Drug Information |
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RIFADIN IV |
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How To Use
- Rifadin Iv is given by injection into a vein usually once or twice a day.
- Avoid injecting intramuscularly or subcutaneously.
- Inject into a vein only.
- Rifadin Iv must be used as prescribed.
- Do not skip doses or stop using this without your doctor s approval.
- Stopping therapy too soon may result in ineffective treatment.
- Full course of therapy may take several months or longer to complete.
Side Effects
- Sore mouth, drowsiness, dizziness or flushing may occur the first several days as your body adjusts to the medication.
- If any of these effects continue or become bothersome, inform your doctor.
- Tell your doctor immediately if any of these unlikely but serious side effects occur: weakness, unusual bruising or bleeding, flu-like symptoms (fever, chills, headache, muscle ache), nausea, vomiting, stomach pain, dark urine, yellowing of the eyes or skin, pale stools, numbness or tingling of the hands or feet, changes in vision, confusion, memory trouble, sore throat.
- Rifadin Iv may cause urine, saliva, tears, stools and sweat to turn red-orange in color.
- Do not be alarmed.
- This will disappear when the medication is stopped.
- Notify your doctor if the injection site becomes swollen or irritated.
- Another injection site may be necessary.
- In the unlikely event you have an allergic reaction to Rifadin Iv, seek immediate medical attention.
- Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing.
- If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Tell your doctor if you have: liver disease, blood disorders, history of alcohol use, any allergies.
- Alcohol can reduce the effectiveness of Rifadin Iv and increase side effects.
- Limit alcohol consumption while taking Rifadin Iv.
- Use caution operating machinery or participating in activities requiring alertness if Rifadin Iv makes you feel drowsy or dizzy.
- Soft contact lenses may be permanently discolored by Rifadin Iv.
- Rifadin Iv should be used only if clearly needed during pregnancy or while breast-feeding.
- Discuss the risks and benefits with your doctor.
Missed Dose
- Try to use each dose at the scheduled time.
- If you miss a dose, use it as soon as remembered; do not use it if it is near the time for the next dose, instead, skip the missed dose and resume your usual dosing schedule.
- Do not double-up the dose to catch up.
Drug Interactions
- Rifadin Iv is not recommended for use with: delavirdine.
- Ask your doctor or pharmacist for more details.
- Inform your doctor about all the medicines you may use (both prescription and nonprescription), especially of: warfarin, oral medicines for diabetes, azole antifungals (e.g., itraconazole, ketoconazole), theophylline, halothane, verapamil, certain protease inhibitors (e.g., nelfinavir), live vaccines, corticosteroids (e.g., prednisone), disopyramide, beta-blockers (e.g., metoprolol), isoniazid, digitoxin, quinidine, mexiletine, phenytoin, cyclosporine, zidovudine.
- Rifampin can decrease the effectiveness of oral contraceptives.
- Discuss the use of other birth control methods with your doctor.
- Also report drugs which cause drowsiness such as sedatives, tranquilizers, psychiatric medicines, anti-seizure or anti-anxiety drugs, narcotic pain relievers and certain antihistamines (e.g., diphenhydramine).
- Do not start or stop any medicine without doctor or pharmacist approval.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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