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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

refacto Kogenate Fs, Kogenate, Helixate, Helixate Fs, Advate Uses Antihemophilic factor is a protein in the blood necessary in forming clots to stop bleeding. Persons with hemophilia A have low levels of this protein leaving them susceptible to bleeding episodes. Refacto is used to temporarily prevent or control bleeding episodes in patients with hemophilia A. Storage Store the medication according to manufacturer s instructions. Check the expiration date on the label and properly discard any unused medication after that time. Overdose If overdose is suspected, contact your local poison control center or emergency room immediately. How To Use Refacto is given by injection into a vein. The rate of injection depends upon patient response but is generally injected over 5 to 10 minutes. The powder and dissolving fluid should be warmed to room temperature before combining if they were refrigerated. After adding the dissolving fluid, swirl the vial gently to completely dissolve the powder. Do not use the mixed solution if you find any floating particles in it or it discolors. The drug should then be started within 1 to 3 hours depending on the product. It may vary from manufacturer to manufacturer. The dose and frequency of use of Refacto will be determined by your condition, weight and situation. Follow your doctor s instructions closely and be sure to ask any questions you may have about this therapy. Side Effects Refacto is generally well tolerated. Mild chills, nausea and irritation at the injection site may occur. In the unlikely event you have an allergic reaction to Refacto, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist. Precautions Tell your doctor your medical history, especially of: other illnesses, allergies (especially to animal proteins). You should check your heart rate before and during injection. The dose or rate of infusion may need to be changed if your heart rate is too fast. Refacto should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if Refacto is excreted into breast milk. Consult your doctor before breast-feeding. Missed Dose It is important that each dose be used as directed. If you miss a dose, contact your doctor to establish a new dosing schedule. Do not double-up the dose to catch up. Drug Interactions Tell your doctor of all over-the-counter and prescription medications you may use. Do not start or stop any medicine without doctor or pharmacist approval.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.