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Mifeprex, also known as RU 486, blocks a hormone (progesterone) which is needed for your pregnancy to continue. When used together with another medicine called misoprostol, mifepristone usually causes an abortion to occur. Use of this treatment must occur within the first 49 days of pregnancy (where day one of pregnancy is defined as the first day of your last menstrual period). Mifepristone is not used if your pregnancy is outside the womb (ectopic pregnancy); it will not cause an abortion in this case. In fact, it may cause an ectopic pregnancy to rupture, resulting in very serious internal or external bleeding.
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| Overview |
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How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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mifeprex
Uses
Mifeprex, also known as RU 486, blocks a hormone (progesterone) which is needed for your pregnancy to continue. When used together with another medicine called misoprostol, mifepristone usually causes an abortion to occur. Use of this treatment must occur within the first 49 days of pregnancy (where day one of pregnancy is defined as the first day of your last menstrual period). Mifepristone is not used if your pregnancy is outside the womb (ectopic pregnancy); it will not cause an abortion in this case. In fact, it may cause an ectopic pregnancy to rupture, resulting in very serious internal or external bleeding.
Storage
- Store at room temperature; 77 degrees F (25 degrees C) away from light and moisture.
Overdose
- If overdose is suspected, contact your local poison control center or emergency room immediately.
- Symptoms of overdose may include severe vaginal bleeding.
Photos
and marketed as Mifeprex TM . |
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PFLI will be making a formal |
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RU486 - Mifeprex (label information |
å ha brukt abortpillen Mifeprex, |
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How To Use
- Before taking Mifeprex, you must read and sign the Patient Agreement form, and read the Medication Guide.
- Mifepristone is taken by mouth as a single dose, as directed by your doctor.
- Two days later, if abortion has not occurred, you take misoprostol by mouth as a single dose.
- You must visit the doctor s office three times to complete your treatment and important examinations.
- This treatment is only given under direct MD supervision, in a doctor s office, clinic, or hospital.
- Be sure to have clear instructions from your doctor regarding whom to call and what to do in case of an emergency.
- Avoid grapefruit juice while using Mifeprex unless your doctor instructs you otherwise.
- If Mifeprex treatment fails to work, abortion surgery is generally performed.
Side Effects
- Nausea, vomiting, diarrhea, headache, dizziness, and fatigue may occur.
- If these effects persist or worsen, notify your doctor promptly.
- Bleeding and cramping are expected during this treatment.
- Usually, the symptoms mean Mifeprexs are working.
- However, sometimes you can have cramps and bleeding and still be pregnant.
- Therefore, you must return for all three of your doctor visits.
- Bleeding and spotting may last up to 30 days, and may be greater than a normal, heavy period.
- In a very few cases, this bleeding will need to be stopped by performing a surgical procedure.
- Tell your doctor immediately if you bleed enough to soak through two thick full-size sanitary pads per hour for two straight hours, or if you are concerned about heavy bleeding.
- Tell your doctor immediately if you have any of these unlikely but serious side effects: fever, fainting, vaginal discomfort or itching, unusual vaginal discharge, any other sign of infection.
- If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Tell your doctor your medical history, including: anemia, if you are a smoker 35 years of age or greater.
- Mifeprex is not recommended for use if you have the following medical conditions: proven or possible pregnancy outside the womb (ectopic pregnancy), an undiagnosed abdominal growth, chronic adrenal gland failure, any allergies (including misoprostol or other prostaglandins), bleeding disorders, certain blood disorders (inherited porphyrias).
- Mifeprex must be used where there is easy access to adequate emergency medical facitilies in case problems develop.
- If you are using an IUD (intrauterine birth control device), it should be removed before mifepristone treatment begins.
- Another pregnancy can occur following this abortion treatment, and before your normal period begins again.
- Birth control can be started as soon as this treatment is successfully completed.
- Mifepristone usually causes fetal death.
- In the unlikely event you have an ongoing pregnancy after treatment, birth defects may result.
- It is not known whether Mifeprex passes into breast milk.
- Since the effects of mifepristone on infants are unknown, breast- feeding women should consult their doctor and determine if they should discard their breast milk for a few days following this treatment.
Missed Dose
- You must follow the dosing schedule as directed by your doctor.
- If you miss an appointment, contact your doctor immediately.
Drug Interactions
- Mifeprex is not recommended for use with: "blood thinners (e.g., anticoagulants such as warfarin, or heparins), long-term corticosteroid therapy (e.g., prednisone).
- Ask your doctor or pharmacist for more details.
- Tell your doctor of all prescription and nonprescription medication you may use, especially of: azole antifungals (e.g., ketoconazole, itraconazole), certain macrolide antibiotics (e.g., erythromycin), rifamycins (e.g., rifampin), dexamethasone, St John s wort, certain anti-seizure drugs (e.g., phenytoin, phenobarbital, carbamazepine).
- Do not eat grapefruit or drink grapefruit juice unless your doctor instructs you otherwise.
- Do not start or stop any medicine without doctor or pharmacist approval.
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| User Medicine Opinions for mifeprex |
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| Low adverse
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| Healing
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| No dependency problems: |
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Sex:
F
Age: 20 Time Taken:
1 times
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| Reason: termination of 5 week pregnancy |
Date:
20 November 2005 |
Side Effects I went to Planned Parenthood, where I was examined, supplied with the abortion pills, RU-486 or, also called as Mifepristone, and a few mild pain killers, and, then, send home with instruction to take the pills by myself. After taking them, I was suffering prolonged, severe and disabling pain. I was crying, moaning from pain for 2 hours, then, just lying down. I had been just lying down for 6 more hours in such severe pain that I wasn't able to move my body, lift my head, and call for help. In 10 hours, when I was able to hardly move, I called emergency of Planned Parenthoodand and told about my pain, on which I was told that they couldn't help me, it was a part of a procedure, and I just gotta take it.
Additional
Thoughts I couldn't take any effective painkillers because the clinics wouldn't let this medicine out. There's no excuse for women to suffer unnecesary pain in these modern times. Women pay from 400$-700$ dollars for pills and deserve better treatment. I'm satisfied with the medicine but I'm not satisfied with the procedure, and I claim that this practice is violation of humans' rights in the US, and something should be done about it.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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