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Estropipate is a female hormone and is usually given to women who no longer produce the proper amount. It is used to reduce menopause symptoms (e.g., hot flashes, vaginal dryness), to prevent bone loss (osteoporosis) in people at high risk, to treat certain cancers in men and women (e.g., certain types of metastatic breast cancer), and to treat other conditions as determined by your doctor. If you are only being treated for vaginal menopause symptoms, products applied locally such as vaginal creams, tablets, or rings should be considered before products taken by mouth or absorbed through the skin. There are several medications (e.g., raloxifene or bisphosphonates) that are safe and effective to prevent or treat bone loss. These medicines should be considered for use before estrogen therapy. If you have other medical conditions as well, and are prescribed estrogens for more than one condition, consult your doctor about your treatment plan and its options.
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Ogen, Ortho-Est
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| Overview |
Photos |
How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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estropipate
Ogen, Ortho-Est
Uses
Estropipate is a female hormone and is usually given to women who no longer produce the proper amount. It is used to reduce menopause symptoms (e.g., hot flashes, vaginal dryness), to prevent bone loss (osteoporosis) in people at high risk, to treat certain cancers in men and women (e.g., certain types of metastatic breast cancer), and to treat other conditions as determined by your doctor. If you are only being treated for vaginal menopause symptoms, products applied locally such as vaginal creams, tablets, or rings should be considered before products taken by mouth or absorbed through the skin. There are several medications (e.g., raloxifene or bisphosphonates) that are safe and effective to prevent or treat bone loss. These medicines should be considered for use before estrogen therapy. If you have other medical conditions as well, and are prescribed estrogens for more than one condition, consult your doctor about your treatment plan and its options.
Storage
- Store at room temperature between 59 and 86 degrees F (15 and 30 degrees C) away from light and moisture.
- Do not store in the bathroom.
- Keep all medicines away from children and pets.
Overdose
- If overdose is suspected, contact your local poison control center or emergency room immediately.
- Symptoms of overdose may include: severe nausea/vomiting or excessive vaginal bleeding.
Photos
ESTROPIPATE |
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ESTROPIPATE |
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estropipate (generic) 1.5 mg |
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estropipate (generic) 0.75 mg |
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How To Use
- Take Estropipate by mouth as directed by your doctor.
- It may be taken with food or immediately after a meal to prevent stomach upset.
- The dosage is based on your medical condition and response to therapy.
- Follow the dosing schedule carefully.
- Read the Patient Information Leaflet available from your pharmacist.
- Consult your doctor or pharmacist if you have any questions.
Side Effects
- Dizziness, lightheadedness, headache, stomach upset, bloating, nausea, weight changes, increased/decreased interest in sex, and breast tenderness may occur.
- If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
- Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (e.g., severe depression, memory loss), calf pain/swelling, sudden severe headache, chest pain, trouble breathing, one-sided weakness, slurred speech, vision changes (e.g., change in contact lens fit, loss of vision), breast lumps, swelling of hands or feet, changes in vaginal bleeding (e.g., spotting, breakthrough bleeding, or prolonged bleeding), unusual vaginal discharge/itching/odor, yellowing of the eyes or skin.
- An allergic reaction to Estropipate is unlikely, but seek immediate medical attention if it occurs.
- Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing.
- If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Estropipate should not be used if you have certain medical conditions.
- Before using Estropipate, consult your doctor or pharmacist if you have: undiagnosed abnormal vaginal bleeding, cancer (e.g., breast cancer - also see USES section), blood clots, active/recent stroke or heart attack, liver disease.
- Before using Estropipate, tell your doctor or pharmacist your medical history, especially of: family medical history (especially breast lumps and cancer), asthma, diabetes, seizures, migraine headaches, heart disease (e.g., high blood pressure, heart attacks, congestive heart failure), kidney disease, low thyroid hormone (hypothyroidism), abnormal calcium level in the blood, depression, high blood pressure during pregnancy (toxemia), yellowing of eyes and skin (cholestatic jaundice) during pregnancy or with past estrogen use, womb problems (e.g., uterine fibroids, endometriosis), cholesterol or lipid problems, gallbladder disease, excessive weight gain, certain blood disorder (porphyria), any allergies.
- Estropipate may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery.
- Limit alcoholic beverages.
- Estropipate may cause a patchy darkening of the skin on the face (melasma).
- Sunlight may intensify this darkening and you may need to avoid prolonged sun exposure and sunlamps.
- Consult your doctor regarding use of sunscreens and protective clothing.
- Cigarette smoking can increase the chance of blood clots while taking Estropipate (especially in women over the age of 35).
- If you will be having surgery or will be confined to a chair or bed for a long period of time (e.g., a long plane flight), notify your doctor beforehand.
- Special precautions may need to be taken in these circumstances while you are taking Estropipate.
- If Estropipate is used in children, their growth pattern should be monitored as Estropipate might stunt their growth.
- Estropipate must not be used during pregnancy.
- If you become pregnant or think you may be pregnant, inform your doctor immediately.
- Estropipate may pass into breast milk and may have undesirable effects on a nursing infant.
- Therefore, breast-feeding while using Estropipate is not recommended.
Missed Dose
- If you miss a dose, take it as soon as you remember.
- If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
- Do not double the dose to catch up.
Drug Interactions
- Before using Estropipate, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: corticosteroids (e.g., prednisone), hydantoins (e.g., phenytoin), warfarin.
- Also tell your doctor or pharmacist if you are taking any medications which affect certain liver enzymes (CYP450-3A4 enzymes), such as: azole antifungals (e.g., ketoconazole, itraconazole), carbamazepine, cimetidine, macrolide antibiotics (e.g., clarithromycin, erythromycin), phenobarbital, rifamycins (e.g., rifampin), ritonavir, St.
- John s wort.
- This product can affect the results of certain lab tests.
- Make sure laboratory personnel and your doctors know you use Estropipate.
- Do not start or stop any medicine without doctor or pharmacist approval.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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