Dihydroergotamine Mesylate

Dihydroergotamine Mesylate Dihydroergotamine - Inj Dihydroergotamine is used to treat migraine headaches and cluster headaches. It is not recommended for migraines affecting only one side of the brain (hemiplegic migraine), the base of the brain/neck area (basilar migraine), or to prevent migraines from occurring.

ALTERNATE NAMES D.h.e.45

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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

dihydroergotamine Mesylate D.h.e.45 Uses Dihydroergotamine is used to treat migraine headaches and cluster headaches. It is not recommended for migraines affecting only one side of the brain (hemiplegic migraine), the base of the brain/neck area (basilar migraine), or to prevent migraines from occurring. Storage Store at room temperature between 59 and 77 degrees F (15 and 25 degrees C) away from light and moisture. Do not refrigerate or freeze this product. Overdose If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: vomiting, slow or shallow breathing, cold/pale or blue-colored hands/feet, seizures. Photos Dihydroergotamine Mesylate Injection Dihydroergotamine Mesylate Injection Dihydroergotamine Mesylate How To Use Learn how to prepare and inject Dihydroergotamine Mesylate and review the dihydroergotamine Patient Information Sheet with your doctor or pharmacist. Inject Dihydroergotamine Mesylate into a vein (IV), into a muscle (IM), or under the skin (SC), as directed by your doctor. The dosage is based on your medical condition and response to therapy. If your headache returns or you have no relief from the first dose, the dose may be repeated 1 hour after the first dose; but only if instructed to do so by your doctor. If giving Dihydroergotamine Mesylate by the IM or SC route, a third dose may be given, if needed, 1 hour after the second dose. If any of the dosing information is unclear, consult your doctor or pharmacist. If given IM or SC, do not exceed 3 ml of Dihydroergotamine Mesylate in a 24-hour time period. If given IV, do not exceed 2 ml of Dihydroergotamine Mesylate in a 24-hour time period. Do not use daily on a regular basis. Do not exceed giving 6 ml of Dihydroergotamine Mesylate in a one-week time period. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Avoid eating grapefruit or drinking grapefruit juice while using Dihydroergotamine Mesylate unless your doctor instructs you otherwise. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist. Side Effects Dizziness, drowsiness, headache, nausea, vomiting, diarrhea, flushing, or increased sweating may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these unlikely but serious side effects occur: swelling, itching, trouble breathing, mental/mood changes (e.g., anxiety), tingling or numbness of the hands/feet, rash, stomach pain. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: muscle pain, chest pain, muscle weakness, unusually fast or slow heartbeat, one-sided weakness, vision problems, slurred speech, confusion. If you notice other effects not listed above, contact your doctor or pharmacist. Precautions Dihydroergotamine Mesylate is not recommended for use if you have the following medical conditions: certain types of heart problems (e.g., ischemic heart disease including angina and heart attacks), uncontrolled high blood pressure, severe blood infections (sepsis), recent blood vessel surgery, blood vessel/circulation problems (e.g., coronary artery disease, peripheral artery disease), severe liver or kidney disease. Tell your doctor your medical history, especially of: liver problems, kidney problems, stroke, high blood pressure, diabetes, high cholesterol, stomach/intestinal problems (e.g., ischemic bowel syndrome), family history of heart disease, tobacco use, any allergies (especially to ergot migraine drugs such as ergotamine). Dihydroergotamine Mesylate may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages; alcohol may also make your headaches worse. Dihydroergotamine Mesylate must not be used in pregnancy. If you become pregnant or think you may be pregnant, inform your doctor immediately. Dihydroergotamine Mesylate passes into breast milk and has had undesirable effects on nursing infants. Breast-feeding while using Dihydroergotamine Mesylate is not recommended. Missed Dose Not applicable. Drug Interactions Dihydroergotamine Mesylate is not recommended for use with: weight loss medicine (e.g., fenfluramine, sibutramine), triptan migraine drugs (e.g., sumatriptan, zolmitriptan), efavirenz. Ask your doctor or pharmacist for more details. Tell your doctor of all prescription and nonprescription medication you may use, especially: decongestants (e.g., pseudoephedrine), nitrate heart medicine (e.g., isosorbide, nitroglycerin), dopamine, certain asthma medications (e.g., albuterol, salmeterol), beta blockers (e.g., metoprolol, propranolol), nicotine-containing products (e.g., tobacco or nicotine patches), SSRI antidepressants (e.g., fluoxetine, fluvoxamine, paroxetine, sertraline), nefazodone, fluconazole, zileuton, clotrimazole, other mild CYP 3A4 enzyme inhibitors. Also see Warning section for additional drug interaction information. Do not start or stop any medicine without doctor or pharmacist approval.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.