D.h.e.45

D.h.e.45 Dihydroergotamine - Inj Dihydroergotamine is used to treat migraine headaches and cluster headaches. It is not recommended for migraines affecting only one side of the brain (hemiplegic migraine), the base of the brain/neck area (basilar migraine), or to prevent migraines from occurring.

ALTERNATE NAMES Dihydroergotamine Mesylate

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D.h.e.45 images: d.h.e.45 prescription drug /side effects/Dihydroergotamine - Inj dihydroergotamine injectable DHE 45 pic 1 d.h.e.45 prescription drug /side effects/Dihydroergotamine - Inj DHE-45 pic 2 d.h.e.45 prescription drug /side effects/Dihydroergotamine - Inj Medications: DHE 45 injectable, pic 4 d.h.e.45 prescription drug /side effects/Dihydroergotamine - Inj DHE-45. Serotonin Receptor Agonist. pic 5

Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

d.h.e.45 Dihydroergotamine Mesylate Uses Dihydroergotamine is used to treat migraine headaches and cluster headaches. It is not recommended for migraines affecting only one side of the brain (hemiplegic migraine), the base of the brain/neck area (basilar migraine), or to prevent migraines from occurring. Storage Store at room temperature between 59 and 77 degrees F (15 and 25 degrees C) away from light and moisture. Do not refrigerate or freeze this product. Overdose If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: vomiting, slow or shallow breathing, cold/pale or blue-colored hands/feet, seizures. Photos dihydroergotamine injectable DHE 45 DHE-45 Medications: DHE 45 injectable, DHE-45. Serotonin Receptor Agonist. How To Use Learn how to prepare and inject D.h.e.45 and review the dihydroergotamine Patient Information Sheet with your doctor or pharmacist. Inject D.h.e.45 into a vein (IV), into a muscle (IM), or under the skin (SC), as directed by your doctor. The dosage is based on your medical condition and response to therapy. If your headache returns or you have no relief from the first dose, the dose may be repeated 1 hour after the first dose; but only if instructed to do so by your doctor. If giving D.h.e.45 by the IM or SC route, a third dose may be given, if needed, 1 hour after the second dose. If any of the dosing information is unclear, consult your doctor or pharmacist. If given IM or SC, do not exceed 3 ml of D.h.e.45 in a 24-hour time period. If given IV, do not exceed 2 ml of D.h.e.45 in a 24-hour time period. Do not use daily on a regular basis. Do not exceed giving 6 ml of D.h.e.45 in a one-week time period. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Avoid eating grapefruit or drinking grapefruit juice while using D.h.e.45 unless your doctor instructs you otherwise. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist. Side Effects Dizziness, drowsiness, headache, nausea, vomiting, diarrhea, flushing, or increased sweating may occur. If any of these effects persist or worsen, notify your doctor. Tell your doctor immediately if any of these unlikely but serious side effects occur: swelling, itching, trouble breathing, mental/mood changes (e.g., anxiety), tingling or numbness of the hands/feet, rash, stomach pain. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: muscle pain, chest pain, muscle weakness, unusually fast or slow heartbeat, one-sided weakness, vision problems, slurred speech, confusion. If you notice other effects not listed above, contact your doctor or pharmacist. Precautions D.h.e.45 is not recommended for use if you have the following medical conditions: certain types of heart problems (e.g., ischemic heart disease including angina and heart attacks), uncontrolled high blood pressure, severe blood infections (sepsis), recent blood vessel surgery, blood vessel/circulation problems (e.g., coronary artery disease, peripheral artery disease), severe liver or kidney disease. Tell your doctor your medical history, especially of: liver problems, kidney problems, stroke, high blood pressure, diabetes, high cholesterol, stomach/intestinal problems (e.g., ischemic bowel syndrome), family history of heart disease, tobacco use, any allergies (especially to ergot migraine drugs such as ergotamine). D.h.e.45 may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages; alcohol may also make your headaches worse. D.h.e.45 must not be used in pregnancy. If you become pregnant or think you may be pregnant, inform your doctor immediately. D.h.e.45 passes into breast milk and has had undesirable effects on nursing infants. Breast-feeding while using D.h.e.45 is not recommended. Missed Dose Not applicable. Drug Interactions D.h.e.45 is not recommended for use with: weight loss medicine (e.g., fenfluramine, sibutramine), triptan migraine drugs (e.g., sumatriptan, zolmitriptan), efavirenz. Ask your doctor or pharmacist for more details. Tell your doctor of all prescription and nonprescription medication you may use, especially: decongestants (e.g., pseudoephedrine), nitrate heart medicine (e.g., isosorbide, nitroglycerin), dopamine, certain asthma medications (e.g., albuterol, salmeterol), beta blockers (e.g., metoprolol, propranolol), nicotine-containing products (e.g., tobacco or nicotine patches), SSRI antidepressants (e.g., fluoxetine, fluvoxamine, paroxetine, sertraline), nefazodone, fluconazole, zileuton, clotrimazole, other mild CYP 3A4 enzyme inhibitors. Also see Warning section for additional drug interaction information. Do not start or stop any medicine without doctor or pharmacist approval. Share and Enjoy!

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User Medicine Opinions for d.h.e.45

Overall: Low adverse Reactions Healing Power: No dependency problems: Cost-Benefit: Sex: F Age: 35 Location: Salem Time Taken: days Reason: migraines Date: 13 January 2008 Side Effects dizziness, anxiety I have been having problems going places, but most of all my left side is weak and the feeling is awful. With stress or anxiety the weakness is stronger. It got rid of my migraine but these symptoms persists. I have only had two shots in three weeks and this is what it does to me. Additional Thoughts The doctors need to research this drug more. Overall: Low adverse Reactions Healing Power: No dependency problems: Cost-Benefit: Sex: F Age: 37 Time Taken: 1 days Reason: SUDDEN HEADACHES Date: 18 January 2006 Side Effects tightness in the chest/left side weakness as the doctors would say. Its called paralysis! Additional Thoughts GAVE THIS MEDECATION A 2 DUE TO IT CAUSED ME TO HAVE A STROKE AND I AM NOW PARTIALLY PARALYZED ON THE LEFT SIDE. I believe some physicians need to learn more about DHE before administering. I had tightness in the chest numbness on the Overall: Low adverse Reactions Healing Power: No dependency problems: Cost-Benefit: Sex: F Age: 37 Time Taken: 1 days Reason: SUDDEN HEADACHES Date: 18 January 2006 Side Effects I GAVE THIS MEDECATION A 2 DUE TO IT CAUSED ME TO HAVE A STROKE AND I AM NOW PARTIALLY PARALYZED ON THE LEFT SIDE. I believe some physicians need to learn more about DHE before administering. I had tightness in the chest numbness on the left side. These side affects were immediately following being given DHE intravenously. Additional Thoughts Overall: Low adverse Reactions Healing Power: No dependency problems: Cost-Benefit: Sex: F Age: 14 Time Taken: 2 days Reason: migraines Date: 17 May 2006 Side Effects nausea, possibly tremors Additional Thoughts I had 4 doses, and before the DHE was given, they gave reglan. the 4th time, i experienced very bad side effects from the reglan: dystonic reactions, and tremors (not sure if it was caused by reglan or DHE). I stopped getting more doses because of the side effects, and it barely helped the migraine i've had for months. Overall: Low adverse Reactions Healing Power: No dependency problems: Cost-Benefit: Sex: F Age: 34 Time Taken: 4 days Reason: migraines Date: 30 September 2006 Side Effects tightness in chest, headache was worsened with each injection, pain in legs, my body/immune system was weakened after treatment and my head still hurts. I have been on bed rest for a while. Additional Thoughts I do not believe doctors have done enough research. I would not recommend this treatment to anyone else.

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