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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Bupropion Wellbutrin XL, Zyban, Wellbutrin, Buproban, Budeprion SR, Once-Daily Wellbutrin XL Uses Treats depression and aids in quitting smoking. This medicine is an antidepressant. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed. Keep all medicine away from children and never share your medicine with anyone. How To Use APPEARANCE: Tablet, Long Acting Tablet. Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to. You may take this medicine with or without food.Swallow the extended-release tablet whole. Do not crush, break, or chew it. You may need to take Wellbutrin® for up to 4 weeks before you feel better. You may need to take Zyban® for 1 to 2 weeks before the date that you have planned to stop smoking. While taking the extended-release form of this medicine, part of the tablet may pass into your stools. This is normal and is nothing to worry about. This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one. Your doctor might ask you to sign some forms to show that you understand this information. Side Effects Call your doctor right away if you notice any of these side effects: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. Fast, slow, or uneven heartbeat. Muscle or joint pain, unexplained fever with rash. Severe agitation or confusion, thoughts of hurting yourself, or other unusual thoughts. Severe or continuing headache, or ringing in your ears. Precautions You should not use this medicine if you have had an allergic reaction to bupropion, or if you have a history of seizures or an eating disorder (such as anorexia nervosa or bulimia nervosa). You should not use this medicine if you have taken an MAO inhibitor drug (Eldepryl®, Nardil®, Marplan®, or Parnate®) within the last 14 days. Do not use Zyban® to quit smoking at the same time you are taking Wellbutrin® for depression, because they are the same medicine. This medicine is not for use in children. Missed Dose If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose. Drug Interactions Make sure your doctor knows if you are pregnant or breast feeding, or if you have liver disease, kidney disease, heart disease, high blood pressure, or diabetes. This medicine may increase your risk of seizures, especially if you have a history of head injury, seizures, brain tumor, severe liver disease, or drug addiction. If you have a seizure, call your doctor right away and do not take any more bupropion. For some children and teenagers, this medicine can increase thoughts of suicide. All of the warnings in this leaflet are true for a child or teenager who is using this medicine. Tell your doctor right away if you start to feel more depressed. Also tell your doctor right away if you have thoughts about hurting yourself. Report any unusual thoughts or behaviors that trouble you, especially if they are new or get worse quickly. Make sure your caregiver knows if you have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. Also tell your doctor if you have sudden or strong feelings, such as feeling nervous, angry, restless, violent, or scared. Let your doctor know if you or anyone in your family has bipolar disorder (manic-depressive) or has tried to commit suicide. Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments. Zyban® is only part of a complete program to help you quit smoking. You will probably be tempted to smoke at times. Have a plan for coping with these situations. This medicine may make you dizzy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.