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This medication is used to help prevent infection from a certain type of bacteria (Salmonella typhi). This infection (typhoid fever) is common when traveling to most areas in Central and South America, Africa, the Near East and Middle East, Southeast Asia, and India. You can get this infection by consuming contaminated food or water. Typhoid fever can cause serious problems, including high fever, severe diarrhea, and dehydration. Many typhoid infections are treatable with antibiotics, but infections with typhoid bacteria that have become more difficult to treat with antibiotics (resistant) are becoming more common and may be fatal. Preventing infection can prevent these problems.Typhoid vaccine contains live bacteria that have decreased ability to cause illness (attenuated). This vaccine causes the body to make immune defensive substances (antibodies) against Salmonella typhi bacteria that can protect you from infection.The vaccine is recommended for persons older than 6 years who are traveling to areas where infection is common, those who are exposed to someone with persistent typhoid infection, and those who work with the bacteria in a laboratory.
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| Overview |
Photos |
How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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Typhoid Vaccine
Uses
This medication is used to help prevent infection from a certain type of bacteria (Salmonella typhi). This infection (typhoid fever) is common when traveling to most areas in Central and South America, Africa, the Near East and Middle East, Southeast Asia, and India. You can get this infection by consuming contaminated food or water. Typhoid fever can cause serious problems, including high fever, severe diarrhea, and dehydration. Many typhoid infections are treatable with antibiotics, but infections with typhoid bacteria that have become more difficult to treat with antibiotics (resistant) are becoming more common and may be fatal. Preventing infection can prevent these problems.Typhoid vaccine contains live bacteria that have decreased ability to cause illness (attenuated). This vaccine causes the body to make immune defensive substances (antibodies) against Salmonella typhi bacteria that can protect you from infection.The vaccine is recommended for persons older than 6 years who are traveling to areas where infection is common, those who are exposed to someone with persistent typhoid infection, and those who work with the bacteria in a laboratory.
Notes
- Do not share this medication with others.
Storage
- Refrigerate between 36-46 degrees F (2-8 degrees C) away from light.
- Do not freeze.
- Discard any product that has not been refrigerated.
- Keep all medicines away from children and pets.
How To Use
- Take this medication by mouth without food, usually every other day for 4 doses or as directed by your doctor.Before talking each dose, inspect the foil blister pack to make sure it is completely sealed.
- Carefully open the blister pack and inspect the capsule to make sure it is not broken or cracked.
- If the capsule is damaged, do not take it.
- Return the damaged dose to the pharmacy for a replacement dose.Swallow the capsule whole about 1 hour before a meal with cold or barely warm liquid.
- Place the capsule in your mouth and swallow with the liquid immediately.
- Do not chew, crush, or hold the capsule in your mouth.The dosing schedule must be followed closely for best effectiveness.
- It may help to mark your calendar with reminders.
- Start the vaccination course 2 weeks before possible exposure to typhoid fever.
- If you have an infection with fever, your doctor may choose to delay vaccination until you are better.If you have previously taken the typhoid vaccine by mouth and are again traveling to a high-risk area, you may need a booster vaccine course if it has been longer than 5 years since your last vaccination.
- Consult your doctor for more information.
Side Effects
- Abdominal pain, nausea, headache, fever, diarrhea, and vomiting may occur.
- If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
- Many people using this medication do not have serious side effects.A very serious allergic reaction to this drug is rare.
- However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Before taking the typhoid vaccine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
- Before using this medicine, consult your doctor or pharmacist if you have: illness with a high fever over 101 degrees F (38 degrees C), persistent diarrhea/vomiting, weakened immune system from other medications (see also Drug Interactions), weakened immune system from other illness (e.g., advanced HIV/AIDS, leukemia, lymphoma, other cancer affecting the bone marrow or lymph nodes), weakened immune system due to radiation treatments, immune problems with certain white blood cells (T-cells), low or abnormal blood antibodies (hypogammaglobulinemia, dysgammaglobulinemia).There is some risk that you will not be fully protected from infection, even if you receive the vaccination.
- Therefore, plan to take precautions to avoid contact with contaminated food or water.
- Ask your doctor or pharmacist for more information.During pregnancy, this medication should be used only when clearly needed.
- Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk.
- Consult your doctor before breast-feeding.
Missed Dose
- It is important to receive each vaccine dose as scheduled.
- If you miss a dose, contact your doctor or pharmacist immediately to establish a new dosing schedule.
Drug Interactions
- Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
- Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This vaccine should not be used with medications that weaken the immune system because you may not develop enough antibodies to the vaccine, and the live bacteria in this vaccine may be able to cause more severe illness.
- Before taking this vaccine, consult your doctor or pharmacist if you use any of the following medications: corticosteroids (e.g., prednisone doses over 7.5 milligrams a day), cancer chemotherapy, organ transplant drugs (e.g., cyclosporine, sirolimus, tacrolimus, mycophenolate), abatacept, adalimumab, alemtuzumab, anakinra, efalizumab, etanercept, infliximab.This vaccine should not be used with medications that can kill the live bacteria in the vaccine.
- Before taking this vaccine, consult your doctor or pharmacist if you use any of the following medications: antibiotics (especially sulfonamides), proguanil.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting the typhoid vaccine course.Polio and yellow fever vaccines taken by mouth may be given with typhoid vaccine.
- If you need the typhoid vaccine and you have received virus vaccines (e.g., flu, hepatitis A/B), do not delay taking the typhoid vaccine course.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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