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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Tobi Uses This drug is used for lung infections (e.g., Pseudomonas) occurring with certain lung conditions (e.g., cystic fibrosis). Notes This medication has been prescribed for your current condition only. Do not share this with others. Medical tests will be performed to monitor your treatment. Storage Store this product in the refrigerator between 36 and 46 degrees F (2-8 degrees C) away from light and moisture. However, if necessary (e.g., transporting this drug) you may store the foil pouches (opened or unopened) at room temperature up to 77 degrees F (25 degrees C) for up to 28 days. Do not freeze. How To Use HOW TO USE THIS MEDICATION: This drug is inhaled via a nebulizer, generally twice daily for 28 days, then 28 days off, then repeat the cycle. It is advised to inhale this product last if other inhalers are used at the same time of day. Follow all directions and learn proper use of this product (information is in the Patient Guide contained with the product), and the nebulizer (including cleaning). Consult your pharmacist. Do not mix this drug with dornase alfa in the nebulizer. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Do this by taking the medication at evenly spaced 12 hour intervals throughout the day and night. Stopping the medication too early may allow bacteria to continue to grow resulting in a relapse of the infection. Continuing the drug beyond the prescribed period may result in increased side effects. Side Effects Hoarseness of voice might occur. If this effect persists or worsens, notify your doctor. Report promptly wheezing or trouble breathing. Unlikely but report promptly ringing in the ears, hearing trouble, dizziness or unsteadiness. Very unlikely but report promptly a major change in urine amount or muscle weakness. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include rash, itching, swelling, dizziness or trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist. Precautions Before using this drug, tell your doctor your entire medical history, including any allergies, hearing or balance (ear) problems, kidney or muscle diseases (e.g., Parkinson's Disease) or asthma. This drug is not recommended for use during pregnancy. Consult your doctor before using this drug. It is not known whether this drug is excreted into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding. Missed Dose If you miss a dose, use it as soon as you remember. If it is less than six hours before the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up. Drug Interactions Tell your doctor of all nonprescription and prescription medication you may use, especially other antibiotics (e.g., other aminoglycosides, vancomycin or minocycline), dornase alfa, "platin"-type cancer drugs (e.g., cisplatin), urea, certain "water pills" such as ethacrynic acid, furosemide or mannitol. Do not start or stop any medicine without doctor or pharmacist approval.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.