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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Tipranavir Aptivus Uses Treats human immunodeficiency virus (HIV) infection. HIV causes acquired immune deficiency syndrome (AIDS). Tipranavir does not cure HIV or AIDS. It will be used with another drug called ritonavir (Norvir®) to slow the progress of the disease. Storage When you first bring this medicine home, store the bottle in the refrigerator until you are ready to open it. Once you have opened the medicine bottle, you may store it at room temperature, away from heat, light, or moisture. The medicine is good for up to 60 days after you open the bottle. After 60 days, throw away any unused capsules and get a new bottle of your medicine. Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed. Keep all medicine away from children and never share your medicine with anyone. How To Use APPEARANCE: Liquid Filled Capsule. Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to. It is best to take this medicine with food or milk. Swallow the capsule whole. Do not crush, break, or chew it. Tipranavir is used with ritonavir (Norvir®) to treat HIV infection. Always take these two medicines together at the same time, unless your doctor tells you otherwise. Take all other medicines your doctor has prescribed at the right time of day. This will make your medicines work better. Do not stop taking your medicine unless your doctor tells you to. Side Effects Call your doctor right away if you notice any of these side effects: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. Dark-colored urine or pale stools. Dry mouth, increased thirst and hunger. Fever, chills, cough, sore throat, and body aches. Lightheadedness or fainting. Nausea, vomiting, loss of appetite, pain in your upper stomach. Sudden or severe headache, problems with vision, speech, or walking. Unusual bleeding, bruising, or weakness. Yellowing of your skin or the whites of your eyes. Precautions You should not use this medicine if you have had an allergic reaction to tipranavir or ritonavir. You should not use this medicine if you have moderate or severe liver disease. Do not use tipranavir if you are also using any of the following medicines: amiodarone (Cordarone®, Pacenone®), astemizole (Hismanal®), bepridil (Vascor®), cisapride (Propulsid®), ergot medicines (Cafergot®, Ergomar®), flecainide (Tambocor®), midazolam (Versed®), pimozide (Orap®), propafenone (Rythmol®), quinidine, terfenadine (Seldane®), or triazolam (Halcion®). Missed Dose If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose. Drug Interactions Make sure your doctor knows if you are pregnant, planning to become pregnant, or breastfeeding. Tell your doctor if you have liver disease (including hepatitis B or C), diabetes, high blood cholesterol, or herpes. Your doctor should know if you think you have been exposed to chickenpox while you are using this medicine. Make sure your doctor knows if you are allergic to sulfa drugs, such as sulfamethoxazole/trimethoprim, Bactrim®, Septra®, or Sulfatrim®. This medicine may cause bleeding in the brain. Make sure your doctor knows if you have a bleeding disorder such as hemophilia, or any medical condition that increases your chance of bleeding. Tell your doctor immediately if you have any unusual or unexplained bleeding. When you start taking HIV medicines, your immune system may get stronger. If you have infections that are hidden in your body, such as pneumonia or tuberculosis, you may notice new symptoms when your body tries to fight them. If this occurs, tell your doctor immediately. Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments. This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds. Your doctor will need to check your blood at regular visits while you are using this medicine. Be sure to keep all appointments. This medicine will not keep you from giving HIV to your partner during sex. Make sure you understand and practice safe sex, even if your partner also has HIV. Do not share needles with anyone. You should not breast feed if you have HIV or AIDS, because you may give the infection to your baby through your breast milk.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.