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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Tacrolimus Prograf Uses Keeps your body from rejecting an organ transplant, such as a kidney, liver, or heart. This medicine may be used with steroids, azathioprine, or mycophenolate mofetil. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed. Keep all medicine away from children and never share your medicine with anyone. How To Use APPEARANCE: Capsule. Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to. It is best to take this medicine on an empty stomach. Side Effects Call your doctor right away if you notice any of these side effects: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. Blistering, peeling, or red skin rash. Change in how much or how often you urinate, or painful urination. Chest pain, shortness of breath, cold sweat, and bluish-colored skin. Confusion, weakness, uneven heartbeat, or numbness or tingling in your hands, feet, or lips. Dark-colored urine or pale stools. Dry mouth, muscle cramps, nausea or vomiting. Fast, slow, or pounding heartbeat. Fever, chills, cough, sore throat, and body aches. Gaining weight around your neck, upper back, breast, face, or waist. Increased thirst or hunger. Lightheadedness, dizziness, or fainting. Numbness or weakness in your arm or leg, or on one side of your body. Problems with hearing, vision, speech, balance, or walking. Rapid weight gain. Seeing or hearing things that are not really there. Seizures, tremors, or muscle twitching. Sudden and severe stomach pain. Swelling in your hands, ankles, or feet. Trouble breathing or swallowing. Unusual bleeding, bruising, or weakness. Yellowing of your skin or the whites of your eyes. Precautions You should not use this medicine if you have had an allergic reaction to tacrolimus. Missed Dose This medicine needs to be given on a fixed schedule. If you miss a dose or forget to use your medicine, call your doctor or pharmacist for instructions. Drug Interactions Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or high blood pressure. Your doctor will need to check your blood or urine at regular visits while you are using this medicine. Be sure to keep all appointments. This medicine lowers the number of some types of blood cells in your body. Because of this, you may bleed or get infections more easily. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers. Some people who have had transplants and used tacrolimus have developed diabetes. This has happened more often in people who are Hispanic or African-American and have had a kidney transplant. You may also have a higher risk of skin cancer or cancer of the lymph system while using tacrolimus. Talk to your doctor if you have concerns about these risks. This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.