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Rifabutin images:

Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Rifabutin Uses This medication is used alone or with another medication to help prevent a serious, spreading infection (Mycobacterium avium complex-MAC) in those with advanced HIV infection. Rifabutin belongs to a class of drugs known as antibiotics that are active against MAC bacteria.This drug may also be used with other medications to treat active MAC infection. It is also used rarely for tuberculosis (TB) infection. Notes Do not share this medication with others.Laboratory and/or medical tests (e.g., MAC cultures, blood counts, liver function tests) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. Storage Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets. How To Use Take this medication by mouth with or without food, usually 1-2 times daily or as directed by your doctor. For the prevention or treatment of MAC, this medication is usually taken long-term.Dosage is based on your age, kidney function, medical condition, and response to therapy.It is very important to continue taking this medication (and all HIV and MAC medications) exactly as prescribed by your doctor.This medication works best when the amount of drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. To help you remember, take it at the same time(s) each day.Do not take more or less of this drug than prescribed or stop taking it (or other MAC medicines) even for a short time unless directed to do so by your doctor. Skipping or changing your dose without approval from your doctor may cause the amount of MAC bacteria to increase, make the infection more difficult to treat (resistant), or worsen side effects. If MAC becomes resistant to this medication, it might also be resistant to other MAC medications.Inform your doctor if your condition persists or worsens. Side Effects Upset stomach, nausea, vomiting, diarrhea, loss of appetite, gas, change in ability to taste, or headache may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: change in skin color, fever, chills, new cough, persistent sore throat, easy bleeding/bruising, weakness/tiredness, fast heartbeat at rest, pale skin, fast breathing at rest.Tell your doctor immediately if any of these rare but very serious side effects occur: muscle aches, persistent nausea, vomiting, weakness, tiredness, stomach/abdominal pain, dark urine, yellowing eyes/skin, eye/vision problems.Tears, saliva, stool, sweat, and urine may be colored brown-orange. This effect is harmless, but clothing, dentures, and contact lenses may become permanently stained.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist. Precautions Before taking rifabutin, tell your doctor or pharmacist if you are allergic to it; or to rifampin; or if you have any other allergies.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: a certain liver/blood condition (porphyria).Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems, alcohol consumption, low white cell count, anemia.This drug may rarely worsen liver problems you may already have. Avoid alcoholic beverages while taking this medication.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding. Missed Dose If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. Drug Interactions Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: delavirdine, voriconazole.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting rifabutin.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: HIV protease inhibitors (e.g., indinavir, ritonavir, nelfinavir), clarithromycin, itraconazole, fluconazole, estrogens.Rifabutin is similar to another antibiotic, rifampin, which is known to interact with many other medications. Tell your doctor or pharmacist if you are also taking erythromycin, fluoroquinolones (e.g., ciprofloxacin), ketoconazole, certain other HIV-medications (e.g., efavirenz, nevirapine), doxycycline, chloramphenicol, mefloquine, atovaquone, tamoxifen, thyroid, levothyroxine, warfarin, cyclosporine, tacrolimus, corticosteroids (e.g., prednisone, dexamethasone), phenytoin, lamotrigine, barbiturates (e.g., Phenobarbital), calcium channel blockers (e.g., verapamil, nifedipine), propranolol, metoprolol, enalapril, losartan, digoxin, mexiletine, propafenone, antidiabetics (e.g., glyburide, glimepiride, repaglinide), simvastatin, fluvastatin, nortriptyline, haloperidol, quetiapine, benzodiazepines (e.g., diazepam, triazolam), buspirone, zolpidem, sunitinib, erlotinib.This medication may decrease the effectiveness of combination-type birth control pills. This can result in pregnancy. You may need to use an additional form of reliable birth control while using this medication. Consult your doctor or pharmacist for details. Share and Enjoy!

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.