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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Ranolazine Ranexa Uses Treats or prevents angina (chest pain) in patients who have taken other medicine for chest pain. This medicine should be used together with amlodipine (Norvasc®), beta-blockers (metoprolol, atenolol), or nitrates (Imdur®). Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed. Keep all medicine away from children and never share your medicine with anyone. How To Use APPEARANCE: Long Acting Tablet. Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to. Do not use this medicine to treat sudden onset of chest pain. You may take this medicine with or without food. Swallow the extended-release tablet whole. Do not crush, break, or chew it. Side Effects Call your doctor right away if you notice any of these side effects: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. Blurred vision. Dizziness, lightheadedness, or fainting. Fast, slow, pounding, or uneven heartbeat. Red or dark brown urine. Severe or increased chest pain. Trouble breathing. Precautions You should not use this medicine if you have had an allergic reaction to ranolazine, or if you have liver disease, history of certain heart rhythm problems, or if you are using medicine for heart rhythm problems such as quinidine, sotalol (Betapace®), or dofetilide (Tikosyn®), or if you are using arsenic trioxide (Trisenox®), cisapride (Propulsid®), medicine for depression (such as amitriptyline, fluoxetine, nortriptyline, Elavil®, Pamelor®, Prozac®, Sarafem®, Vivactil®), certain antibiotics (such as erythromycin, levofloxacin, moxifloxacin, sparfloxacin, Avelox®, Levaquin®, Zagam®), or medicine to treat mental illness (such as haloperidol, mesoridazine, pimozide, prochlorperazine, quetiapine, thioridazine, ziprasidone, Compazine®, Geodon®, Haldol®, Mellaril®, Orap®, Serentil®, Seroquel®). Do not use this medicine if you are also using diltiazem, verapamil, medicine to treat fungus infections such as ketoconazole (Nizoral®), or medicine to treat HIV or AIDS (such as ritonavir). Missed Dose If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose. Drug Interactions Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, low potassium in your blood, or a family history of a heart condition called congenital long QT syndrome. This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert. You may also feel lightheaded when standing or sitting up straight, so stand up or sit up slowly. Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments. If your symptoms do not improve or if they get worse, call your doctor.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.