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Drug Guide    R   RSV Immune Globulin (Human)

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   RSV Immune Globulin (Human)

RSV Immune Globulin (Human)
IV


This medication is used in infants who have lung disease (e.g., bronchopulmonary dysplasia) or who were born prematurely. It is used to prevent severe lung infections caused by a certain virus (RSV). This medication is made from healthy human blood that has a high level of certain defensive substances (antibodies). These antibodies help the body to fight infections caused by RSV. Using this medication has been shown to reduce the severity of the RSV infection, thereby reducing the number and length of hospital stays caused by RSV.

 
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Overview Photos How To Use Side Effects Precautions Missed Dose Drug Interactions

RSV Immune Globulin (Human)

Uses
This medication is used in infants who have lung disease (e.g., bronchopulmonary dysplasia) or who were born prematurely. It is used to prevent severe lung infections caused by a certain virus (RSV). This medication is made from healthy human blood that has a high level of certain defensive substances (antibodies). These antibodies help the body to fight infections caused by RSV. Using this medication has been shown to reduce the severity of the RSV infection, thereby reducing the number and length of hospital stays caused by RSV.
Notes
  • Laboratory and/or medical tests (e.g., heart/respiratory rate, kidney function) should be performed periodically to monitor your child's progress or check for side effects.
  • Consult the doctor for more details.

Storage
  • Refrigerate between 36-46 degrees F (2-8 degrees C) away from light.
  • Do not freeze.
  • The medication in each vial should be used only once.
  • Throw away any unused portion.
  • Keep all medicines away from children and pets.

Overdose
  • Symptoms of overdose may include: swelling ankles/feet, trouble breathing.

How To Use
  • This medication is given by injection into a vein by a health care professional.
  • Before using this product, check it visually for cloudiness, particles, or discoloration.
  • If any are present, do not use the liquid.
  • Do not shake the vial or cause the medication to foam.
  • Health care professionals must follow all the manufacturer's instructions for properly mixing and giving this drug.
  • If you have any questions about the use of this medication, consult your pharmacist.The health care professional will start the medication slowly while monitoring your child closely.
  • If there are few or no side effects, the medication will be given faster.Dosage is based on your child's weight, medical condition, and response to treatment.
  • The maximum recommended dosage is 750 milligrams per kilogram per monthly infusion.
  • This medication is usually given before the start of the RSV season, then given monthly throughout the RSV season (e.g., November through April, depending on area).Your child should receive this medication regularly to get the most benefit from it.
  • To help you remember, mark the days on the calendar when your child needs to receive the medication.

Side Effects
  • Fever, nausea/vomiting, dizziness, flushing, chest tightness, muscle/joint pain, or pain/swelling at the injection site may occur.
  • Tell your child's doctor or pharmacist promptly if any of these effects occur, persist, or worsen.
  • The infusion may need to be stopped or given more slowly.Remember that the doctor has prescribed this medication because he or she has judged that the benefit to your child is greater than the risk of side effects.
  • Many people using this medication do not have serious side effects.Tell the doctor immediately if any of these unlikely but serious side effects occur: change in the amount of urine, swelling ankles/feet, sudden weight gain, shortness of breath, fast heartbeat, changes in skin color/temperature.This medication is made from human blood.
  • Even though donors are carefully screened and this medication goes through a special manufacturing process, there is a very small chance that your child may get infections from the medication (e.g., viral infections such as hepatitis).
  • Tell the doctor immediately if your child develops any signs of hepatitis/another infection, including fever, persistent sore throat, unusual tiredness, persistent nausea/vomiting, yellowing eyes/skin, dark urine.Treatment with this medication may rarely cause a serious swelling of the brain (aseptic meningitis syndrome) several hours to 2 days after treatment.
  • Seek immediate medical attention if your child develops severe headache, drowsiness, high fever, eye pain/sensitivity to light, muscle stiffness, or severe nausea/vomiting.A very serious allergic reaction to this drug is rare.
  • However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact the doctor or pharmacist.

Precautions
  • Before receiving RSV-IGIV, tell your child's doctor or pharmacist if he or she is allergic to it; or to other human immunoglobulin preparations; or if he or she has any other allergies.Before your child receives this medication, tell the doctor or pharmacist his or her medical history, especially of: a certain immune system problem (IgA deficiency), a certain blood problem (paraproteinemia), kidney disease, diabetes, too much/little body water (e.g., swelling of arms/legs, dehydration), a serious blood infection (sepsis), heart disease.While your child is receiving this medication and for 10 months afterward, this medication may prevent a good response to live virus vaccines (e.g., measles, mumps, rubella).
  • Consult the doctor for more details, and discuss any planned immunizations/vaccinations.During pregnancy, this medication should be used only when clearly needed.
  • Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk.
  • Consult your doctor before breast-feeding.

Missed Dose
  • It is important that each dose be used as scheduled.
  • If your child misses a dose, contact the doctor immediately to establish a new dosing schedule.

Drug Interactions
  • The doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring your child for them.
  • Do not start, stop, or change the dosage of any medicine before checking with the doctor or pharmacist first.Before your child receives this medication, tell the doctor or pharmacist of all prescription and nonprescription/herbal products your child may use, especially of: drugs that may harm the kidneys (e.g., aminoglycosides such as gentamicin).
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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