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Promethazine-Phenylephrine images:

Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Promethazine-Phenylephrine Uses This medication is used to treat runny nose, coughing, sneezing, itchy nose/throat, and itchy/watery eyes caused by allergies or the common cold.Promethazine belongs to a class of drugs known as antihistamines. It works by preventing the effects of a certain natural chemical (histamine).Phenylephrine belongs to a class of drugs known as decongestants. It causes shrinking/narrowing of blood vessels in the nose and sinuses to reduce nasal congestion (stuffy nose). Notes Do not share this medication with others.Unless otherwise directed by your physician, drink plenty of fluids (especially water) while taking this medication. It will help to break up mucus and clear congestion.Do not take this medication for several days before you have an allergy test because results can be affected.Promethazine may affect the results of some pregnancy tests. Consult your doctor for more details. Storage Store at room temperature between 59-77 degrees F (15-25 degrees C) away from sunlight. Keep the container tightly closed. Do not store in the bathroom. Keep all medicines away from children and pets. Overdose Symptoms of overdose may include: nausea, vomiting, blurred vision, drowsiness, slowed breathing, widened/fixed pupils, seizures, deep sleep, loss of consciousness. How To Use Take this medication by mouth with or without food, usually every 4-6 hours or as directed by your doctor. This medication may be taken with food if stomach upset occurs.Dosage is based on your medical condition and response to therapy.Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same times each day.Inform your doctor if your condition persists or worsens after 7 days. Side Effects Drowsiness, dizziness, headache, upset stomach, nausea, or dry mouth/nose/throat may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: fast/slow/irregular heartbeat, difficulty breathing, vomiting, decreased coordination, fainting, ringing in the ears, vision changes (e.g., blurred/double vision), difficulty urinating, shaking (tremor), mental/mood changes (e.g., nervousness, irritability, confusion, hallucinations).Stop taking this medication and seek immediate medical attention if any of these rare but very serious side effects occur: slow/shallow breathing, signs of infection (e.g., fever, persistent sore throat), severe abdominal pain, persistent nausea/vomiting, easy bleeding/bruising, yellowing of eyes/skin, dark urine, abnormal/involuntary movements (e.g., fixed upward stare, neck twisting, tongue movements).Promethazine may infrequently cause a very serious (rarely fatal) nervous system disorder (neuroleptic malignant syndrome). If you notice any of the following rare but very serious side effects, stop taking this medication and seek immediate medical attention: severe muscle stiffness, mental/mood changes (e.g., sudden confusion, extreme drowsiness), very high fever, seizures, irregular/fast heartbeat, increased sweating.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist Precautions See also Warning section.Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to any other phenothiazines (e.g., prochlorperazine); or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (e.g., angina, irregular heartbeat), kidney/liver problems, breathing problems (e.g., asthma, emphysema, sleep apnea), difficulty urinating (e.g., due to an enlarged prostate), stomach/bowel problems (e.g., blockage, ulcer), high blood pressure, overactive thyroid (hyperthyroidism), diabetes, a certain eye problem (narrow-angle glaucoma), seizures, blood/immune system problems (e.g., bone marrow depression).This drug may make you dizzy or drowsy; use caution while engaging in activities requiring alertness such as driving or using machinery. Children should be supervised to avoid injury during bicycle riding or other possibly hazardous activities. Limit alcoholic beverages.To minimize dizziness and lightheadedness, get up slowly from a sitting or lying position.This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors.Children may be more sensitive to the effects of the drug, especially breathing problems such as slow/shallow breathing. Children may also experience excitability rather than drowsiness. Special caution should be taken in children with a family history of sudden infant death syndrome (SIDS), those who have a severe loss of fluid (dehydration), and those who are hard to wake up from sleep.The elderly may be more sensitive to the effects of the drug, especially drowsiness and confusion.This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.It is unknown if this medication passes into breast milk. However, it may have undesirable effects on a nursing infant. Therefore, breast-feeding while using this medication is not recommended. Consult your doctor before breast-feeding. Missed Dose If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. Drug Interactions Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine), epinephrine for low blood pressure, metrizamide, sibutramine, cabergoline, pergolide, halofantrine, pimozide.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this medication.Avoid taking MAO inhibitors within 2 weeks before, during, and after treatment with this medication. In some cases a serious (possibly fatal) drug interaction may occur.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: narcotic pain medications (e.g., codeine), tramadol, muscle relaxants, medicine for sleep/anxiety (e.g., alprazolam, diazepam, zolpidem), bupropion, tricyclic antidepressants (e.g., amitriptyline), psychiatric medicines (e.g., chlorpromazine, risperidone, trazodone), drugs for Parkinson's disease (e.g., anticholinergics such as benztropine, trihexyphenidyl), anti-seizure drugs (e.g., carbamazepine), scopolamine, antispasmodics (e.g., atropine, belladonna alkaloids), other antihistamines (e.g., diphenhydramine, dimenhydrinate), cough-and-cold products, diphenhydramine or other antihistamines applied to the skin (e.g., anti-itch cream, ointment, spray). Share and Enjoy!

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.