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Medroxyprogesterone is a type of female hormone (progestin). This medication is similar to the progesterone that your body naturally makes and is given to replace the hormone when your body is not making enough of it. This medication has several uses. In women who are not pregnant and not going through menopause, this medication is used to treat abnormal bleeding from the uterus and to restore normal menstrual periods in women who have stopped having them for several months (amenorrhea).Medroxyprogesterone is also used as part of combination hormone replacement therapy with estrogens to reduce menopause symptoms (e.g., hot flashes). Medroxyprogesterone is added to estrogen replacement therapy to reduce the risk of cancer of the uterus.This medication must not be used to test for pregnancy.
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How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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Prodroxy
Uses
Medroxyprogesterone is a type of female hormone (progestin). This medication is similar to the progesterone that your body naturally makes and is given to replace the hormone when your body is not making enough of it. This medication has several uses. In women who are not pregnant and not going through menopause, this medication is used to treat abnormal bleeding from the uterus and to restore normal menstrual periods in women who have stopped having them for several months (amenorrhea).Medroxyprogesterone is also used as part of combination hormone replacement therapy with estrogens to reduce menopause symptoms (e.g., hot flashes). Medroxyprogesterone is added to estrogen replacement therapy to reduce the risk of cancer of the uterus.This medication must not be used to test for pregnancy.
Notes
- Do not share this medication with others.Keep all appointments with your doctor and the laboratory.
- You should have a complete physical examination that includes blood pressure measurements and breast/pelvic examinations at regular intervals (e.g., once a year) or as directed by your doctor.
- Follow your doctor's instructions on how to examine your own breasts and report any lumps immediately.
- You should also be regularly screened for cervical cancer (e.g., Pap test) and have periodic mammograms as determined by your doctor.
- Consult your doctor for more details.
Storage
- Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture.
- Do not store in the bathroom.
- Keep all medicines away from children and pets.
Overdose
- Symptoms of overdose may include severe nausea and vomiting.
How To Use
- Read the Patient Information Leaflet provided by your pharmacist before you start using this drug and each time you get a refill.
- If you have any questions, consult your doctor or pharmacist.Take this medication by mouth as directed by your doctor.
- Follow the dosing schedule carefully.
- Ask your doctor if you have any questions.
- The dosage is based on your medical condition and response to therapy.For use in combination hormone replacement therapy with estrogens, take this medication usually once daily for the prescribed number of days each month as directed.For the treatment of stopped menstrual periods (amenorrhea) and abnormal bleeding from the uterus, take this drug usually once daily for 5-10 days during the second half of the planned menstrual cycle or as directed by your doctor.
- Withdrawal bleeding usually occurs within 3-7 days after you stop taking the medication.Inform your doctor if your condition does not improve or if it worsens.
Side Effects
- Nausea, bloating, breast tenderness, headache, change in vaginal discharge, mood swings, blurred vision, dizziness, drowsiness, or weight gain/loss may occur.
- If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
- Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these serious side effects occur: unusual vaginal bleeding (e.g., spotting, breakthrough bleeding), mental/mood changes (e.g., depression, memory loss), swelling of the hands/feet, frequent/burning/painful urination, breast lumps, dark patches on the skin or face (melasma), yellowing eyes/skin, unusual tiredness.This medication may rarely cause very serious (possibly fatal) problems from blood clots (e.g., heart attack, stroke, blood clots in the lungs or legs, blindness).
- Seek immediate medical attention if you experience any of the following: chest/jaw/left arm pain, weakness on one side of the body, slurred speech, sudden vision changes (e.g., blurred/double vision, loss of vision, bulging eyes), confusion, sudden severe headache, severe dizziness, fainting, trouble breathing, coughing up blood, pain/redness/swelling/weakness of the arms/legs, calf pain/swelling that is warm to the touch.A very serious allergic reaction to this drug is rare.
- However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Before taking medroxyprogesterone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
- Some Canadian brands of this medication may come from a soybean source.
- If you are allergic to soybeans/peanuts, check with your pharmacist about your particular brand.This medication should not be used if you have certain medical conditions.
- Before using this medicine, consult your doctor or pharmacist if you have: history of blood clots, history of bleeding in the brain, liver disease, cancer of the breast or other female organs, vaginal bleeding of unknown cause, a loss of pregnancy with some tissue remaining in the uterus ("missed abortion"), recent stroke or heart attack (within 1 year).Before using this medication, tell your doctor or pharmacist your medical history, especially of: family medical history (especially breast lumps and cancer), kidney disease, obesity, heart disease (e.g., past heart attacks, coronary artery disease, congestive heart failure), high blood pressure, seizures, migraine headaches, asthma, high blood levels of cholesterol/fats, depression, diabetes, strokes.This drug may make you dizzy or drowsy.
- Use caution while driving, using machinery, or doing any activity that requires alertness.
- Limit alcoholic beverages.Notify your doctor beforehand if you will be having surgery or will be confined to a chair/bed for a long time (e.g., a long plane flight).
- You may need to stop the medication for a time or take special precautions because of the increased risk for blood clots.
- Ask your doctor for more details.Do not smoke.
- Smoking combined with this medication further increases your risk for strokes, blood clots, high blood pressure, and heart attacks.This medication may cause blotchy, dark areas on your skin (melasma).
- Sunlight may worsen this effect.
- Avoid prolonged sun exposure, tanning booths, and sunlamps.
- Use a sunscreen, and wear protective clothing when outdoors.This medication must not be used during pregnancy because it may harm an unborn baby, especially during the first 4 months of pregnancy.
- If you become pregnant or think you may be pregnant, inform your doctor immediately.This drug passes into breast milk.
- Consult your doctor before breast-feeding.
Missed Dose
- If you miss a dose, take it as soon as you remember.
- If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
- Do not double the dose to catch up.
Drug Interactions
- Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
- Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially: aminoglutethimide.This medication can affect the results of certain lab tests.
- Make sure laboratory personnel and all your doctors know you use this medication.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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