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This combination medication is used to treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses (e.g., sinusitis, bronchitis). Promethazine is an antihistamine that relieves watery eyes, itchy eyes/nose/throat, runny nose, and sneezing. Phenylephrine is a decongestant that relieves stuffy nose symptoms. Codeine is a narcotic cough suppressant (antitussive) that affects a certain part of the brain, reducing the urge to cough.
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Phenyleph-Promethazine-Cod images:
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| Overview |
Photos |
How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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Phenyleph-Promethazine-Cod
Uses
This combination medication is used to treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses (e.g., sinusitis, bronchitis). Promethazine is an antihistamine that relieves watery eyes, itchy eyes/nose/throat, runny nose, and sneezing. Phenylephrine is a decongestant that relieves stuffy nose symptoms. Codeine is a narcotic cough suppressant (antitussive) that affects a certain part of the brain, reducing the urge to cough.
Notes
- Do not share this medication with others.
- It is against the law.Do not take this medication for several days before allergy testing because test results can be affected.
Storage
- Store in a tightly closed container at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture.
- Do not store in the bathroom.
- Do not freeze.
- Keep all medicines away from children and pets.
Overdose
- Symptoms of overdose may include: confusion, cold/clammy skin, fast/slow/irregular heartbeat, slow/shallow breathing, seizures, fainting.
How To Use
- Take this medication by mouth with or without food, usually every 4 to 6 hours as needed with a full glass of water (8 ounces or 240 milliliters) or as directed by your doctor.
- This medication can be taken with food if stomach upset occurs.
- Drink plenty of fluids when you use this medication unless otherwise directed by your doctor.Use a medication-measuring device to carefully measure the prescribed dose.
- Do not use a household spoon.This medication may cause dependence, especially if it has been used regularly for an extended time (more than a few weeks) or if it has been used in high doses.
- In such cases, if you suddenly stop this drug, withdrawal reactions may occur.
- Such reactions can include anxiety, restlessness, sweating, shaking chills, nausea, vomiting, and diarrhea.
- Report any such reactions to your doctor immediately.
- When stopping extended, regular treatment with this drug, gradually reducing the dosage as directed will help prevent withdrawal reactions.
- Consult your doctor or pharmacist for more details.Though very unlikely, abnormal drug-seeking behavior (addiction) is possible with this medication.
- Do not increase your dose, take it more frequently, or take it for a longer time than prescribed.
- Properly stop the medication when so directed.When used for an extended time, this medication may not work as well and may require different dosing.
- Talk with your doctor if this medication stops working well.Tell your doctor if your condition persists for more than 1 week, if it worsens, or if it occurs with fever, rash, or persistent headache.
- These may be symptoms of a serious medical problem and should be checked by a doctor.
Side Effects
- Drowsiness, dizziness, headache, lightheadedness, blurred vision, upset stomach, nausea, nervousness, trouble sleeping, constipation, increased sweating, or dry mouth may occur.
- If any of these effects persist or worsen, tell your doctor or pharmacist promptly.This medication can dry up and thicken mucus in your lungs, making it more difficult to breathe and clear your lungs.
- To help prevent this effect, drink plenty of fluids unless otherwise directed by your doctor.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
- Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: involuntary behaviors/movements (e.g., fixed upward stare, neck twisting, tongue movements), mental/mood changes (e.g., confusion, hallucinations), ringing in the ears, shaking (tremors), slow/shallow breathing, trouble urinating, weakness.Seek immediate medical attention if any of these rare but very serious side effects occur: chest pain, dark urine, easy bruising/bleeding, slow heartbeat, persistent nausea/vomiting, severe abdominal pain, yellowing eyes/skin.This drug may infrequently cause a very serious (rarely fatal) nervous system disorder (neuroleptic malignant syndrome).
- If you notice any of the following unlikely but very serious side effects, stop taking this medication and seek immediate medical attention: fast/irregular heartbeat, very high fever, mental/mood changes (e.g., confusion, extreme drowsiness), seizure, severe muscle stiffness.A very serious allergic reaction to this drug is rare.
- However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other side effects not listed above, contact your doctor or pharmacist.
Precautions
- See also Warning section.This medication should not be used in a person who is unconscious or has severe breathing problems (e.g., respiratory depression, hypercapnia).Before taking this medication, tell your doctor or pharmacist if you are allergic to any of its ingredients; or to narcotic pain relievers (e.g., morphine); or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: abdominal problems (e.g., chronic constipation, ileus, pancreatitis), adrenal gland problem (e.g., Addison's disease), blood/immune system problems (e.g., bone marrow depression), brain disorders (e.g., seizures, head injury, tumor, increased intracranial pressure), breathing problems (e.g., asthma, emphysema), diabetes, glaucoma, heart problems (e.g., angina, irregular heartbeat), high blood pressure, liver disease, mental/mood problems (e.g., depression, psychosis), a certain spinal problem (kyphoscoliosis), stomach/intestinal problems (e.g., ulcers, blockage), thyroid disease, trouble urinating (e.g., due to enlarged prostate or urethral stricture), use/abuse of drugs/alcohol.This drug may make you dizzy or drowsy.
- Use caution while driving, using machinery, or doing any activity that requires alertness.
- Limit the use of alcohol and certain other medications that may cause drowsiness (see also Drug Interactions).
- To reduce dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.This medication may make you more sensitive to the sun.
- Avoid prolonged sun exposure, tanning booths, and sunlamps.
- Use a sunscreen and wear protective clothing when outdoors.This medication may contain sugar and/or alcohol.
- Caution is advised if you have diabetes, alcohol dependence, or liver disease.
- Ask your doctor or pharmacist about using this product safely.The elderly may be more sensitive to the effects of this drug, especially dizziness, drowsiness, mental/mood changes, and low blood pressure.During pregnancy, this medication should be used only if clearly needed.
- It is not recommended for use in high doses or for long periods during the last 3 months of pregnancy due to increased risk for serious side effects in a newborn baby (e.g., withdrawal symptoms such as irritability, abnormal/persistent crying, diarrhea, seizures).
- Tell your doctor immediately if you notice any of these symptoms in your newborn.
- Discuss the risks and benefits with your doctor.This medication may pass into breast milk and have undesirable effects on a nursing infant.
- Consult your doctor before breast-feeding.
Missed Dose
- If you are prescribed this medication on a regular schedule and miss a dose, take it as soon as you remember.
- If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
- Do not double the dose to catch up.
Drug Interactions
- Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
- Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: epinephrine for low blood pressure, MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine), metrizamide, sibutramine.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this medication.
- Avoid taking MAO inhibitors for 2 weeks before, during, and 2 weeks after treatment with this medication.
- In some cases a serious (possibly fatal) drug interaction may occur.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: anticholinergic drugs (e.g., benztropine, belladonna alkaloids), cancer chemotherapy (e.g., methotrexate), certain inhaled anesthetics (e.g., halothane), cimetidine, guanethidine, guanadrel, methyldopa, narcotic antagonists (e.g., naltrexone, naloxone), quinidine, reserpine.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, trazodone).Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain ingredients that cause drowsiness.
- Ask your pharmacist about using those products safely.Also report the use of drugs that might increase seizure risk when combined with this medication such as isoniazid (INH), phenothiazines (e.g., thioridazine), theophylline, or tricyclic antidepressants (e.g., amitriptyline), among others.
- Consult your doctor or pharmacist for details.This medication may interfere with certain laboratory tests (e.g., some pregnancy tests, blood sugar tests), possibly causing false test results.
- Make sure laboratory personnel and all your doctors know you use this drug.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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