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This medication is used to treat moderate to severe pain. It may also be used before surgery, during childbirth, and for relief of anxiety from severe shortness of breath due to severe breathing problems. Oxymorphone injection is a narcotic pain reliever. It acts on certain centers in the brain to give you pain/anxiety relief.
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| Overview |
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How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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Oxymorphone
Uses
This medication is used to treat moderate to severe pain. It may also be used before surgery, during childbirth, and for relief of anxiety from severe shortness of breath due to severe breathing problems. Oxymorphone injection is a narcotic pain reliever. It acts on certain centers in the brain to give you pain/anxiety relief.
Notes
- Do not share this medication with others.
- It is against the law.This medication has been prescribed for your current condition only.
- Do not use it later for another condition unless told to do so by your doctor.
- A different medication may be necessary in that case.
Storage
- Store multi-dose vials or ampules at room temperature at 77 degrees F (25 degrees C) away from light.
- Brief storage between 59-86 degrees F (15-30 degrees C) is permitted.
- Keep all medicines away from children and pets.
Overdose
- Symptoms of overdose may include: slow breathing, slow heartbeat, loss of consciousness, bluish skin/lips/nails.
How To Use
- This medication is given by injection into a vein or muscle or under the skin.
- This medication is used every 4-6 hours.
- Use exactly as prescribed by your doctor.The dosage is based on your medical condition and response to therapy.
- Pain medications work best if they are used when the first signs of pain occur.
- If you wait until the pain has worsened, the medication may not work as well.Learn the proper way to safely give injections and store and discard syringes and needles.
- This medication may cause dependence, especially if it has been used regularly for an extended time or if it has been used in high doses.
- In such cases, withdrawal reactions (e.g., shakiness, sweating, nausea) may occur if you suddenly stop this drug.
- To prevent withdrawal reactions when stopping extended, regular treatment with this drug, gradually reduce the dosage as directed.
- Consult your doctor or pharmacist for more details, and report any withdrawal reactions immediately.Though very unlikely, abnormal drug-seeking behavior (addiction) is possible with this medication.
- Do not increase your dose, take it more frequently, or take it for a longer time than prescribed.
- Properly stop the medication when so directed.
- When used for an extended period, this medication may not work as well and may require different dosing.
- Talk with your doctor if this medication stops working well.Tell your doctor if your pain persists or worsens after 24 hours when first starting this medication or after a dose change.
Side Effects
- Nausea, vomiting, constipation, lightheadedness, dizziness, drowsiness, or dry mouth may occur.
- Less common side effects may include redness at the injection site.
- If any of these effects persist or worsen, tell your doctor or pharmacist promptly.To prevent constipation, maintain a diet adequate in fiber, and drink plenty of water.
- If you become constipated while using this drug, consult your pharmacist for help in selecting a laxative (e.g., stimulant-type with stool softener).Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
- Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: slow/shallow breathing, mental/mood changes (e.g., agitation, hallucinations, confusion), vision problems, flushing of the face, slow/fast/irregular heartbeat, fainting, loss of appetite, difficulty starting urination, decreased sexual ability/interest.Tell your doctor immediately if any of these rare but very serious side effects occur: severe stomach/abdominal pain, change in the amount of urine, seizures.A very serious allergic reaction to this drug is rare.
- However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Before using oxymorphone injection, tell your doctor or pharmacist if you are allergic to it; or to other narcotic pain medications; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
- Before using this medicine, consult your doctor or pharmacist if you have: severe breathing problems (e.g., respiratory depression, asthma attack), certain bowel diseases (e.g., paralytic ileus, toxic megacolon, acute abdomen), intoxication with medications that depress the nervous system or your breathing (brain/respiratory depressants such as alcohol or tranquilizers/sedatives), heart rhythm problems, heart failure due to long-term lung disease, brain disorders (e.g., head injury/tumor, increased intracranial pressure), uncontrolled seizures, a certain type of infectious diarrhea (pseudomembranous colitis).Before using this medication, tell your doctor or pharmacist your medical history, especially of: seizures, lung diseases (e.g., chronic obstructive pulmonary disease-COPD, low oxygen in the blood, high carbon dioxide in the blood), low blood pressure, alcohol withdrawal, disease of the pancreas (e.g., pancreatitis), mental/mood disorders (e.g., toxic psychosis), a certain spinal problem (kyphoscoliosis), gallbladder disease, personal or family history of regular use/abuse of drugs/alcohol, kidney disease, liver disease, adrenal gland problem (e.g., Addison's disease), difficulty urinating (e.g., due to enlarged prostate or urethral stricture), severe obesity, underactive thyroid (hypothyroidism), sleep apnea.This drug may make you dizzy or drowsy.
- Use caution while driving, using machinery, or taking part in any other activity that requires alertness.
- Avoid alcoholic beverages because they may increase the risk of this drug's side effects.To lower your risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially slow/shallow breathing, low blood pressure, and drowsiness.During pregnancy, this medication should be used only when clearly needed.
- Discuss the risks and benefits with your doctor.
- Infants born to mothers who have used this medication for an extended time may have withdrawal symptoms such as irritability, abnormal/persistent crying, vomiting, or diarrhea.
- Tell your doctor immediately if you notice any of these symptoms in your newborn.
- If this medication is used during childbirth, labor may be lengthened, and the baby's heartbeat may become temporarily abnormal.It is not known if this drug passes into breast milk.
- Because of the potential risk to the infant, breast-feeding is not recommended while using this drug.
- Consult your doctor before breast-feeding.
Missed Dose
- If you miss a dose, use it as soon as you remember.
- If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
- Do not double the dose to catch up.
Drug Interactions
- Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
- Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medication because very serious interactions may occur: naltrexone.If you are currently using the medication listed above, tell your doctor or pharmacist before starting oxymorphone.Before using oxymorphone, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: anticholinergic medications (e.g., scopolamine), MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine, rasagiline), cimetidine.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants (e.g., methocarbamol), narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone).Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain ingredients that cause drowsiness.
- Ask your pharmacist about using those products safely.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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