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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Oxsoralen Ultra Uses This medication is used along with controlled ultraviolet light (UVA) to help control severe psoriasis. Methoxsalen belongs to a class of drugs known as psoralen photosensitizers. It works by making certain parts of the skin more sensitive to UVA light, causing a skin reaction that helps to shrink psoriasis plaques.This drug may also be used for other skin problems (e.g., vitiligo, cutaneous t-cell lymphoma). Notes Do not share this medication with others.Laboratory and/or medical tests (e.g., eye exams, routine blood tests) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. Storage Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets. How To Use Read the Patient Information Leaflet provided by your pharmacist before you start using methoxsalen and each time you get a refill. If you have any questions, consult your doctor or pharmacist.Avoid sunlight for 24 hours before taking methoxsalen and having a PUVA treatment.This medication is only taken on days you are having UVA light treatments. Take this medication by mouth, usually 90 minutes to 2 hours before treatment or exactly as directed by your doctor. To decrease nausea, take methoxsalen with low-fat food or milk. After taking the capsules, avoid sunlight (including sunlight through windows) and wear UVA-blocking glasses for 24 hours. Avoiding the sun protects the skin from getting too many UVA rays, which could lead to sunburn. The UVA-blocking glasses prevent possible cataracts from UVA rays. If you must be in the sun, wear clothing that covers all skin (including arms/legs) and a hat to protect your head and face.During the treatment, your eyes will be protected from the UVA rays by special goggles provided by your doctor.Treatments may be repeated 2 to 4 times per week depending on your response to treatment. Less frequent treatments may be used to maintain results.Dosage of methoxsalen is based on your weight, medical condition, and response to treatment. The amount of UVA light for each treatment is based on your skin type and response to treatment.Tell your doctor immediately if you develop worsening skin burns or your skin condition persists or worsens. Side Effects Nausea may occur with methoxsalen. Less common side effects may include sleeping problems and nervousness. Methoxsalen with UVA treatments may cause skin reddening/burning/tanning, itching, skin drying, blisters on the hands/feet. If any of these effects persist or worsen, or if any burning worsens severely, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: depression, pain with brown/yellow/white color change in the nails, worsened psoriasis, increased hair growth on the face, ankle swelling.Tell your doctor immediately if any of these rare but very serious side effects occur: formation of new/unusual skin sores, decreased or clouded vision.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist. Precautions See also Warning section.Before using methoxsalen, tell your doctor or pharmacist if you are allergic to it; or to sunlight; or if you have any other allergies.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: unusual or bad reaction to other psoralen products, skin cancer (melanoma, basal cell or squamous cell carcinomas), conditions that make you sensitive to light (e.g., lupus, certain porphyrias, xeroderma pigmentosum, albinism), no natural lens in the eye.Before using this medication, tell your doctor or pharmacist your medical history, especially of: coal tar/UVA treatment, radiation treatment, arsenic treatments, cataracts, liver problems, kidney problems, heart problems.Caution is advised when using this drug in the elderly because they may be more likely to have serious side effects, including cataracts, heart problems, skin cancers, kidney problems, or liver problems.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding. Missed Dose This medication is only taken before a UVA treatment. If you forget to take your dose as scheduled or miss a treatment, contact your doctor's office to reschedule your treatment. Drug Interactions Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of other photosensitizing medications you may be taking/using such as: anthralin, coal tar, griseofulvin, phenothiazines (e.g., promethazine, thiothixene), nalidixic acid, sulfa antibiotics (e.g., sulfamethoxazole, sulfisoxazole), fluroquinolone antibiotics (e.g., ciprofloxacin), bacteriostatic soaps, tetracycline, doxycycline, thiazide diuretics (e.g., hydrochlorothiazide), certain dyes (methylene blue, toluidine blue, rose bengal, methyl orange).If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting methoxsalen.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.