Olanzapine IM - Drug Information and Side Effects on Drug3k.com


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Olanzapine IM images:

Overview

Photos

How To Use

Side Effects

Precautions

Missed Dose

Drug Interactions

Olanzapine IM

Uses
This medication is used to treat severe agitation associated with certain mental/mood conditions (schizophrenia, bipolar mania). It works by helping to restore the balance of certain natural chemicals in the brain (neurotransmitters).This drug has been used to treat dementia-related behavior problems (e.g., agitation, aggression) when standard treatments (e.g., behavioral therapy, cholinesterase inhibitors) have not been successful.This drug should only be used for the condition for which it was prescribed.
Notes

Do not share this medication with others.Laboratory and/or medical tests (e.g., fasting blood sugar-FBS, weight, blood pressure, blood cholesterol/triglyceride levels, liver function tests) should be performed periodically to monitor your progress or check for side effects.
Consult your doctor for more details.Go for regular eye exams as part of your regular health care, and to check for any unlikely, but possible, eye problems.

Storage

Before mixing, store at room temperature between 68-77 degrees F (20-25 degrees C) away from light.
Do not freeze.
Brief storage between 59-86 degrees F (15-30 degrees C) is permitted.
After mixing, store between 68-77 degrees F (20-25 degrees C) for up to 1 hour.
Discard the drug if not used within 1 hour of mixing.
Do not store in the bathroom.
Keep all medicines away from children and pets.

Overdose

Symptoms of overdose may include: severe drowsiness, slurred speech, slowed breathing, or seizures.

How To Use

This medication is given by a slow, intramuscular injection (IM) by a healthcare professional.
The dosage is based on your medical condition and response to therapy.Follow all directions for proper mixing.
Do not mix with other medications.
Consult the pharmacist for details.When mixed, this liquid should be clear and yellow in appearance.
Before using, check this product visually for particles.
If present, do not use the liquid.This medication is intended for short-term control of acute agitation symptoms.
If you require continuous treatment for your condition, your doctor may switch you to an oral medication.

Side Effects

Dry mouth, constipation, nausea, dizziness, stomach pain, weight gain, drowsiness, back pain, or redness/pain/swelling at the injection site may occur.
If any of these effects persist or worsen, notify your doctor or pharmacist promptly.This drug can make you dizzy or light-headed after rising from a seated or lying position.
If you are dizzy or light-headed after using this drug, it is best to lie down until you no longer feel that way when trying to get up.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects.
Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these serious side effects occur: ankle/leg swelling, agitation, confusion, fast or slow heartbeat, slowed breathing, restlessness, weakness, difficulty speaking, numbness or tingling of hands or feet, trouble walking (abnormal gait), painful menstrual periods, pink urine, tremor.Tell your doctor immediately if any of these unlikely but serious side effects occur: chest pain, yellowing of the eyes or skin, weakness on one side of the body, sudden vision changes, headache, painful urination, other eye problems, seizures, difficulty swallowing.This drug may infrequently make your blood sugar level rise, which can cause or worsen diabetes.
High blood sugar can rarely cause serious conditions such as diabetic coma.
Tell your doctor immediately if you develop symptoms of high blood sugar, such as unusual increased thirst and urination.
If you already have diabetes, be sure to check your blood sugars regularly.This drug may also cause significant weight gain and a rise in your blood cholesterol (or triglyceride) levels.
These effects, along with diabetes, may increase your risk for developing heart disease.
Discuss the risks and benefits of treatment with your doctor.
(See also Notes section.)This medication may rarely cause a serious condition called neuroleptic malignant syndrome (NMS).
Seek immediate medical attention if you develop the following: fever, muscle stiffness, severe confusion, sweating, fast or irregular heartbeat.Olanzapine may rarely cause a condition known as tardive dyskinesia.
In some cases, this condition may be permanent.
Tell your doctor immediately if you develop any unusual/uncontrolled movements (especially of the face or tongue).In rare instances, this medication may increase your blood level of a certain hormone (prolactin).
For females, this rare increase in prolactin levels may result in unwanted breast milk, the menstrual period stopping, or difficulty becoming pregnant.
For males, it may result in decreased sexual ability, inability to produce sperm, or enlarged breasts.
If you develop any of these symptoms, tell your doctor immediately.For males, in the very unlikely event you have a painful or prolonged erection lasting 4 or more hours, stop using this drug and seek immediate medical attention, or permanent problems could occur.A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.
Symptoms of a serious allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Before taking olanzapine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
Before using this medicine, consult your doctor or pharmacist if you have a history of the following: neuroleptic malignant syndrome (see also Side Effects section).Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems, low blood pressure, breast cancer, stroke, dementia, Alzheimer's disease, seizures, prostate problems, glaucoma (narrow angle type), intestinal disease, difficulty swallowing, tardive dyskinesia (see also Side Effects section), smoking.Also tell your doctor or pharmacist if either you or a family member has a history of the following: diabetes, heart disease, high blood cholesterol/triglyceride levels, high blood pressure, obesity.This drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery.
Avoid alcoholic beverages.This medication can make you prone to heat stroke.
Avoid activities that might cause you to overheat (e.g., doing strenuous work, exercising in hot weather, or using hot tubs).Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially dizziness, drowsiness, or seizures.This medication should be used only when clearly needed during pregnancy.
Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk.
Breast-feeding is not recommended while using this drug.
Consult your doctor before breast-feeding.

Missed Dose

Not applicable.

Drug Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
Do not start, stop, or change the dosage of any medicine before checking with them first.The following medication should not be used with olanzapine because a very serious interaction may occur: sibutramine.If you are currently using the medication listed above, tell your doctor or pharmacist before starting olanzapine.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: carbamazepine, fluvoxamine, drugs for high blood pressure, omeprazole, drugs for Parkinson's disease, rifampin.Report drugs that cause drowsiness such as medicine for sleep (e.g., sedatives), tranquilizers, anti-anxiety drugs (e.g., diazepam), narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., phenothiazines such as chlorpromazine, or tricyclics such as amitriptyline), anti-seizure drugs (e.g., phenytoin), muscle relaxants, antihistamines that cause drowsiness (e.g., diphenhydramine).Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain ingredients that cause drowsiness.
Ask your pharmacist about the safe use of those products.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.