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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Nisoldipine Uses Nisoldipine is used with or without other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Nisoldipine is called a calcium channel blocker. It works by relaxing blood vessels so blood can flow more easily. This medication may also affect heart rate. Notes Do not share this medication with others. Lifestyle changes such as stress reduction programs, exercise, and dietary changes may increase the effectiveness of this medicine. Talk to your doctor or pharmacist about lifestyle changes that might benefit you.Laboratory and/or medical tests (e.g., liver function tests, heart exam, blood pressure) may be performed from time to time to monitor your progress or check for side effects. Consult your doctor for more details.Have your blood pressure checked regularly while taking this medication. Discuss with your doctor how to monitor your own blood pressure. Storage Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets. Overdose Symptoms of overdose may include: severe dizziness/fainting, fast/irregular heartbeat, confusion. How To Use Take this medication by mouth, usually once daily in the morning without food or as directed by your doctor.Swallow the tablet whole. Do not crush, chew or cut the tablet. Doing so can destroy the long action of the drug and may increase side effects.Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for more details.The dosage is based on your age, medical condition, body size and response to therapy.Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time each day. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. For the treatment of high blood pressure, it may take up to a week before the full benefit of this drug takes effect.Do not suddenly stop taking this medication without consulting your doctor. Your condition may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.Inform your doctor if your condition worsens (e.g., your routine blood pressure readings increase). Side Effects Headache, swelling of the ankles/feet, flushing, dizziness, nausea, and a feeling of your heart pounding in your chest may occur as your body adjusts to the medication. Less common side effects may include tiredness, acne, dry skin, stomach pain, and gas. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: shortness of breath, persistent tiredness, fast/irregular/very slow heartbeat, unusual dreams, mental/mood changes, decreased sexual ability/desire, fainting, muscle pain/cramps, joint pain, diarrhea, vision changes, hair loss.Tell your doctor immediately if any of these rare but very serious side effects occur: easy bruising, rectal bleeding, severe abdominal pain, new or worsening chest pain, sudden dizziness/fainting, severe/persistent nausea, seizures, confusion, weakness on one side of the body, slurred speech.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist. Precautions Before taking nisoldipine, tell your doctor or pharmacist if you are allergic to it; or to other calcium channel blockers (e.g., nimodipine, nifedipine) or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, certain types of heart disease (angina, coronary artery disease), heart failure, neuromuscular problems (e.g., myasthenia gravis).This drug may make you dizzy; use caution while engaging in activities requiring alertness such as driving or using machinery.Before having surgery, tell your doctor or dentist that you are taking this medication.This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.It is not known if this medication passes into breast milk. Consult your doctor before breast-feeding. Missed Dose If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. Drug Interactions See also the How to Use section.Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: phenytoin, rifamycins including rifabutin and rifampin, phenobarbital and other barbiturates, carbamazepine, dexamethasone, St John's wort.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting nisoldipine.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: cimetidine, azole antifungals (e.g., fluconazole, ketoconazole, itraconazole), calcium supplements, dantrolene.Check the labels on all your medicines (e.g., cough-and-cold products, diet aids, nonsteroidal anti-inflammatory drugs-NSAIDs for pain/fever reduction) because they may contain ingredients that could increase your blood pressure or heart rate (e.g., pseudoephedrine, phenylephrine, chlorpheniramine, diphenhydramine, clemastine, ibuprofen, naproxen). Ask your pharmacist about using those products safely.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.