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Enoxaparin is used to prevent and treat harmful blood clots. Preventing harmful blood clots helps to reduce the risk of a stroke or heart attack. This medication helps keep your blood flowing smoothly by lowering the activity of clotting proteins in the blood. Enoxaparin is sometimes commonly referred to as a "blood thinner," but its more correct term is "anticoagulant." It is a type of heparin.Conditions which increase your risk of developing blood clots include certain types of surgeries (e.g., knee or hip replacement), long periods of being immobile, certain types of heart attack, and a specific type of chest pain called unstable angina. For some medical conditions, enoxaparin may be used in combination with other "blood thinners.
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| Overview |
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How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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Lovenox SubQ
Uses
Enoxaparin is used to prevent and treat harmful blood clots. Preventing harmful blood clots helps to reduce the risk of a stroke or heart attack. This medication helps keep your blood flowing smoothly by lowering the activity of clotting proteins in the blood. Enoxaparin is sometimes commonly referred to as a "blood thinner," but its more correct term is "anticoagulant." It is a type of heparin.Conditions which increase your risk of developing blood clots include certain types of surgeries (e.g., knee or hip replacement), long periods of being immobile, certain types of heart attack, and a specific type of chest pain called unstable angina. For some medical conditions, enoxaparin may be used in combination with other "blood thinners.
Notes
- Do not share this medication with others.Laboratory and/or medical tests (e.g., blood counts including platelets, checking your stool for blood) should be performed periodically to monitor your progress or check for side effects.
- Additional lab tests (anti-factor Xa blood levels) should be performed in certain cases, especially if you have severe kidney disease, are pregnant and have artificial heart valves, or if lack of effectiveness of enoxaparin is suspected.
- Consult your doctor for more details.
Storage
- Store the US product at room temperature (77 degrees F or 25 degrees C).
- Brief storage between 59-86 degrees F (15-30 degrees C) is permitted.Store the Canadian product at room temperature 59-86 degrees F (15 to 30 degrees C) away from heat .
- Do not store the multiple dose vials for more than 7 days after the first use.Store the medication away from light and moisture.
- Do not store in the bathroom.
- Keep all medicines away from children and pets.
Overdose
- Symptoms of overdose may include excessive bleeding and bruising.
How To Use
- If you are giving the shots yourself, you will be trained by a health care professional on how to properly prepare, inject, and use this product.
- If any of the information is unclear, consult your health care professional.
- Inject enoxaparin under the skin (subcutaneously) usually once or twice a day, or use as directed by your doctor.
- Do not inject into a muscle or a vein.Before using this product, check it visually for particles or discoloration.
- If either is present, do not use this product.
- To minimize irritation, change the injection site with each dose.
- To minimize bruising, do not rub the injection site after a shot.Learn how to store and discard needles and medical supplies safely.
- Consult your pharmacist for more details.Use this medication regularly in order to get the most benefit from it.
- To help you remember, use it at the same time(s) each day.
- Dosage and length of treatment are based on your medical condition (e.g., severe kidney disease) and response to therapy.
- Dosage may also be based on your weight for some conditions.
Side Effects
- See also Warning.Mild irritation, pain, bruising, redness, or swelling at the injection site may occur.
- Fatigue or fever may also occur.
- If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects.
- Many people using this medication do not have serious side effects.This medication can cause bleeding if its effect on your blood clotting proteins is too much.
- Tell your doctor immediately if any of these unlikely but serious signs of bleeding occur: unusual pain/swelling/discomfort, unusual or prolonged bleeding, unusual or easy bruising.Tell your doctor immediately if any of these rare but very serious signs of bleeding occur: dark urine, black stools, severe headache, confusion, vision changes, unusual dizziness, fainting, seizures, weakness, numbness.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.
- Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Before taking enoxaparin, tell your doctor or pharmacist if you are allergic to it; or to heparin, pork products, or the preservative in the medication vial (benzyl alcohol); or if you have any other allergies.This medication should not be used if you have certain medical conditions.
- Before using this medicine, consult your doctor or pharmacist if you have: serious active bleeding.Before using enoxaparin, tell your doctor or pharmacist your medical history, especially of: artificial heart valves, severe kidney disease, liver disease, bleeding or blood disorders (e.g., low platelet counts), low platelet counts after previous heparin treatment, stroke, uncontrolled severe high blood pressure, certain eye problems (e.g., diabetic retinopathy), certain stomach/intestinal problems (e.g., active or recent ulcers), recent spinal procedure or puncture, recent eye/brain/spinal cord surgery.Limit alcohol while taking this drug because it may increase the risk of stomach bleeding.Before having surgery, tell your doctor or dentist that you are using enoxaparin.This medication can infrequently cause heavy bleeding.
- Be extra careful to avoid injuries (e.g., contact sports).
- Use an electric razor when shaving and a soft toothbrush when brushing your teeth.Caution is advised when using this drug in the elderly because they may be more sensitive to its side effects, especially bleeding.A preservative (benzyl alcohol) which is found in enoxaparin vials can infrequently cause serious problems (sometimes death), if given in large amounts (more than 100 milligrams per kilogram daily) to an infant during the first months of life (neonatal period).
- The risk is also greater with low birth weight infants.
- Symptoms include sudden gasping, low blood pressure, or a very slow heartbeat.
- Report these symptoms to the doctor immediately if they should occur.
- If possible, a preservative-free product, such as enoxaparin in the manufacturer's syringes, should be used when treating neonates.Enoxaparin should be used only when clearly needed during pregnancy.
- Discuss the risks and benefits with your doctor.
- Pregnant women with artificial heart valves need close monitoring (see Notes).
- Since enoxaparin vials contain benzyl alcohol that can affect the unborn baby, the preservative-free drug in the manufacturer's syringes is preferred.It is not known whether this drug passes into breast milk.
- Consult your doctor before breast-feeding.
Missed Dose
- Try not to miss any doses.
- If you miss a dose, use it as soon as you remember.
- If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
- Do not double the dose to catch up.
Drug Interactions
- Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it.
- Do not start, stop, or change the dosage of any medicine before checking with them first.This drug should not be used with the following medication because very serious interactions may occur: mifepristone.If you are currently using mifepristone, tell your doctor or pharmacist before starting enoxaparin.Before using enoxaparin, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use.This medication is sometimes used together with other drugs that have "blood thinning" or anti-platelet effects such as aspirin, clopidogrel, or warfarin.
- When these combinations are prescribed by your doctor, you will require closer monitoring to minimize your risk of bleeding.
- Keep all medical and laboratory appointments.Check all prescription and nonprescription medicine labels carefully since many contain pain relievers/fever reducers (NSAIDs such as ibuprofen, naproxen, or aspirin) which can increase the risk of bleeding/anti-platelet effect when used with enoxaparin.
- Low-dose aspirin, as prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention or to prevent clotting of artificial heart valves (usually these dosages are 81-325 milligrams per day), should be continued.
- Consult your doctor or pharmacist for more details.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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