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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Liquaemin Sodium Uses This medication is used to prevent and treat blood clots. It may be used to treat blood clots in the lungs/legs. It may also be used to prevent blood clots after surgery, during dialysis, when collecting blood samples, or when a person is unable to move for a long time. Heparin helps to keep blood flowing smoothly by making a certain natural substance in your body (anti-clotting protein) work better. It is known as an anticoagulant. Notes Laboratory and/or medical tests (e.g., hematocrit, complete blood count, platelet counts, activated partial thromboplastin time, test for blood in stool) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. Storage This medication must be stored properly. Review storage instructions with the pharmacist. Check the expiration date before using. Keep all medicines away from children and pets. Overdose Symptoms of overdose may include: easy/unusual bruising, bleeding such as persistent nosebleeds, blood in urine, black stools. How To Use This medication is given by injection by a health care professional. Learn all preparation and usage instructions for this product. Before using this product, check it visually for particles or discoloration. If either is present, do not use the liquid. If you have questions about the use of this medication, consult the doctor or pharmacist.Do not inject this medication into a muscle.For products given under the skin, clean the injection site with rubbing alcohol before injecting each dose. It is important to change the location of the injection site daily to avoid problem areas under the skin.Dosage is based on your medical condition, weight, and response to treatment.Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same times each day. It is important to continue using this medication even if you feel well. Do not suddenly stop taking this medication without consulting your doctor.Your doctor may direct you to switch to an anticoagulant taken by mouth (e.g., warfarin). Use this medication and any new medication exactly as directed by your doctor.Tell your doctor if your condition persists or worsens. Side Effects Mild pain/redness/irritation at the injection site may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.This medication can cause bleeding if it has too much effect on your blood. Tell your doctor immediately if you develop any signs of serious bleeding, including unusual pain/swelling/discomfort, prolonged bleeding from cuts or gums, persistent nosebleeds, unusually heavy/prolonged menstrual periods, unusual/easy bruising, dark urine, black stools, severe headache, unusual dizziness. (See also Precautions section regarding HIT)Tell your doctor immediately if any of these unlikely but serious side effects occur: swelling at injection site, bone pain, easily broken bones.Some patients can have certain bad reactions to heparin (heparin-induced thrombocytopenia-HIT or heparin-induced thrombocytopenia and thrombosis-HITT). This can occur during treatment and up to several weeks after treatment with heparin has stopped.Seek immediate medical attention if any of these rare but very serious side effects occur (see also Precautions section regarding HIT): pain/loss of feeling in the arms/legs, change in color of the arms/legs, chest pain, trouble breathing, confusion, weakness on one side of the body, slurred speech, vision changes.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist. Precautions Before using heparin, tell your doctor or pharmacist if you are allergic to it; or to pork products; or if you have any other allergies.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: very low platelet count (thrombocytopenia), uncontrollable bleeding.Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe high blood pressure (hypertension), heart problems (e.g., infection of the heart, heart attack), recent surgery/procedure, cancer, bleeding/clotting disorders (e.g., hemophilia, antithrombin III deficiency), stomach/intestinal ulcers or tube drainage, liver disease, kidney disease, current/recent bleeding (e.g., from wounds, menstrual period).Before having surgery, tell your doctor or dentist that you are using this medication.This medication contains sodium. Consult your doctor or pharmacist if you are on a salt-restricted diet or if you have a condition that could be worsened by an increase in salt intake (e.g., congestive heart failure).The elderly may be at greater risk for bleeding while using this drug.A preservative (benzyl alcohol) that might be found in this product can infrequently cause serious (sometimes fatal) problems if given in large amounts (more than 100 milligrams per kilogram daily) to an infant during the first months of life. The risk is greater with low-birth-weight infants. Symptoms include sudden gasping, low blood pressure, very slow heartbeat. If you notice any of these symptoms in your newborn, report them to the doctor immediately. If possible, a preservative-free product should be used when treating newborns.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.This medication does not pass into breast milk. However, consult your doctor before breast-feeding. Missed Dose If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. Drug Interactions Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medication because very serious interactions may occur: mifepristone.If you are currently using the medication listed above, tell your doctor or pharmacist before starting heparin.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: antihistamines (e.g., diphenhydramine), antithrombin III, digoxin, nicotine (e.g., patch, gum), nitroglycerin given by injection, other drugs that can cause bleeding/bruising (e.g., anticoagulants such as warfarin, antiplatelet drugs including NSAIDs such as ketorolac), tetracyclines.Check all prescription and nonprescription medicine labels carefully because many contain pain relievers/fever reducers (NSAIDs such as ibuprofen, naproxen, or aspirin) that can increase the risk of bleeding when used with heparin. Low-dose aspirin should be continued if it has been prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 milligrams per day). Consult your doctor or pharmacist for more details.Do not mix or infuse heparin together in the same line or catheter with doxorubicin, droperidol, ciprofloxacin, or mitoxantrone.Cigarette smoking decreases blood levels of this medication. Tell your doctor if you smoke or if you have recently stopped smoking.This medication may interfere with certain laboratory tests (including certain liver function tests, prothrombin time), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.