Lansoprazole-NaproxenOral - Drug Information and Side Effects on Drug3k.com


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Lansoprazole-Naproxen images:

Overview

Photos

How To Use

Side Effects

Precautions

Missed Dose

Drug Interactions

Lansoprazole-Naproxen

Uses
This medication is used to treat the signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis in patients who have had a stomach ulcer. This product is two separate medications, lansoprazole and naproxen.Naproxen is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking the enzyme in your body that makes a natural hormone-like substance (prostaglandins) which in turn helps to reduce pain and swelling (inflammation). The benefits of naproxen may include reduced joint swelling/pain, morning stiffness, night pain, and pain at rest.Lansoprazole blocks acid production in the stomach. It is known as a proton pump inhibitor (PPI).Naproxen can cause stomach ulcers, especially in patients with a history of stomach ulcers. When taken together, these medications may provide the benefits of naproxen, while reducing the risk of new ulcers that can occur with naproxen use.
Notes

Do not share this medication with others.Laboratory and/or medical tests (e.g., complete blood count, liver and kidney function tests) should be performed periodically to monitor your progress or check for side effects.
Consult your doctor for more details.

Storage

Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture.
Brief storage between 59-86 degrees F (15-30 degrees C) is permitted.
Do not store in the bathroom.
Keep all medicines away from children and pets.

Overdose

Symptoms of overdose may include: severe stomach pain, coffee ground-like vomit, trouble breathing, extreme drowsiness, loss of consciousness, seizures.

How To Use

Read the Medication Guide provided by your pharmacist before you start using this medication and each time you get a refill.
If you have any questions regarding the information, consult your doctor or pharmacist.Take by mouth exactly as directed by your doctor.
The dosage is based on your medical condition and response to therapy.
To reduce your risk of stomach bleeding and other side effects, take this medication at the lowest effective dose for the shortest possible time.
Do not increase your dose, take it more frequently, or take it for a longer time than prescribed.
For ongoing conditions such as arthritis, continue taking this medication as directed.
Discuss the risks and benefits with your doctor or pharmacist.This product comes in a convenience package (blister card).
Each blister card provides enough drug for one week of therapy, and is marked to allow easy dosing of the two medications.The naproxen comes as a tablet that should be taken twice daily (in the morning and evening) with a full glass (8 oz or 240 ml) of water unless your doctor directs you otherwise.
Do not lie down for at least 30 minutes after taking this drug.
If stomach upset occurs while taking this medication, take it with food, milk, or an antacid.The lansoprazole comes as a capsule and should be taken once daily before eating with the morning dose of naproxen.
Swallow this medication whole.
If you have difficulty swallowing it, the capsule may be opened and the contents sprinkled onto soft food (e.g., apple sauce, cottage cheese, yogurt), or emptied into a small amount (2 oz or 60 ml) of juice and taken as directed.
Rinse the container with an additional small amount of juice and drink the contents to make sure the entire dose is taken.
Do not chew the food/medication mixture or prepare a supply in advance; this may destroy the drug and/or increase side effects.Use this medication regularly in order to get the most benefit from it.
Remember to use it at the same time(s) each day.Inform your doctor if your condition persists or worsens.

Side Effects

See also Warning section.Upset stomach, nausea, vomiting, heartburn, headache, diarrhea, constipation, drowsiness, and dizziness may occur.
If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects.
Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these serious side effects occur: stomach pain, swelling of the hands or feet, sudden or unexplained weight gain, ringing in the ears (tinnitus).Tell your doctor immediately if any of these unlikely but serious side effects occur: vision changes, rapid or pounding heartbeat, easy bruising or bleeding.Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: change in amount of urine, severe headache, very stiff neck, mental/mood changes, persistent sore throat or fever, signs of vitamin B-12 deficiency with long-term (over 3 years) treatment (e.g., unusual weakness, sore tongue, numbness or tingling of the hands/feet).This drug may rarely cause serious (possibly fatal) liver disease.
If you notice any of the following highly unlikely but very serious side effects, stop taking naproxen and consult your doctor or pharmacist immediately: yellowing eyes and skin, dark urine, unusual/extreme tiredness.A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.
Symptoms of a serious allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Before taking lansoprazole and naproxen, tell your doctor or pharmacist if you are allergic to either of them; or to aspirin or other NSAIDs (e.g., ibuprofen, celecoxib); or to other proton-pump inhibitors such as omeprazole, pantoprazole; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
Before using this medicine, consult your doctor or pharmacist if you have: severe kidney disease, aspirin-sensitive asthma (a history of worsening breathing with runny/stuffy nose after taking aspirin or other NSAIDs), recent heart bypass surgery (CABG).Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, poorly controlled diabetes, stomach/intestinal/esophagus problems (e.g., bleeding, ulcers, recurring heartburn), heart disease (e.g., congestive heart failure, history of heart attack), high blood pressure, stroke, swelling (edema, fluid retention), dehydration, blood disorders (e.g., anemia), bleeding or clotting problems, asthma, growths in the nose (nasal polyps), history of an allergic reaction with symptoms of lip/tongue/throat swelling (angioedema).Some symptoms may actually be signs of a more serious condition.
Tell your doctor immediately if you have: heartburn combined with lightheadedness/sweating/dizziness, chest pain or shoulder/jaw pain (especially with trouble breathing), pain spreading to arms/neck/shoulders, unexplained weight loss.This medication contains salt (sodium).
Tell your doctor if you are on a salt-restricted diet.This drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery.
Limit alcoholic beverages.This medication may cause stomach bleeding.
Daily use of alcohol and tobacco, especially when combined with this medicine, may increase the risk of stomach bleeding.
Consult your doctor or pharmacist for more information.This medication may make you more sensitive to the sun.
Avoid prolonged sun exposure, tanning booths or sunlamps.
Use a sunscreen and wear protective clothing when outdoors.Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially stomach bleeding and kidney effects.This medication should be used only when clearly needed during the first 6 months of pregnancy.
It is not recommended for use during the last 3 months of pregnancy due to the potential for harm to an unborn baby and interference with normal labor/delivery.
Discuss the risks and benefits with your doctor.Naproxen passes into breast milk.
It is not known if lansoprazole passes into breast milk.
Breast-feeding is not recommended while using this product.

Missed Dose

If you miss a dose, use it as soon as you remember.
If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
Do not double the dose to catch up.

Drug Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
Do not start, stop, or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: atazanavir, cidofovir, pemetrexed.If you are currently using any of these medications, tell your doctor or pharmacist before starting lansoprazole and naproxen.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: anti-platelet drugs (e.g., cilostazol, clopidogrel), alendronate, other medications for arthritis (e.g., aspirin, methotrexate), "blood thinners" (e.g., warfarin, enoxaparin, heparin), cilostazol, corticosteroids (e.g., prednisone), cyclosporine, high blood pressure drugs (including ACE inhibitors such as captopril, angiotensin II receptor antagonists such as losartan, and beta-blockers such as metoprolol), lithium, other NSAIDs (e.g., ibuprofen, celecoxib), probenecid, theophylline, voriconazole, "water pills" (diuretics such as furosemide, hydrochlorothiazide, triamterene).Lansoprazole can decrease the effectiveness of certain drugs which require stomach acid in order to be absorbed.
Before using this medication, consult your doctor or pharmacist on how to manage such a potential interaction if you are taking the following drugs: ampicillin, azole antifungals (e.g., ketoconazole, itraconazole), iron supplements.Based on information for similar drugs, lansoprazole may increase the amount of digoxin that is absorbed into your blood.
Consult your doctor or pharmacist for details if you also take digoxin.This product can affect the results of certain lab tests.
Make sure laboratory personnel and your doctors know you use this drug.Check all prescription and nonprescription medicine labels carefully for other pain/fever drugs (NSAIDs such as aspirin, celecoxib, ibuprofen).
These drugs are similar to naproxen, so taking one of these drugs while also taking this medication may increase your risk of side effects.
However, if your doctor has prescribed low doses of aspirin to prevent heart attack or stroke (usually at dosages of 81-325 milligrams a day), you should continue to take the aspirin.
Daily use of NSAIDs (e.g., ibuprofen) may decrease aspirin's ability to prevent heart attack/stroke.
Consult your doctor or pharmacist for more details and to discuss other possible treatments (e.g., acetaminophen) for your pain/fever.Do not take this medication with any other medications that contain naproxen.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.