KenazineOral - Drug Information and Side Effects on Drug3k.com


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Overview

Photos

How To Use

Side Effects

Precautions

Missed Dose

Drug Interactions

Kenazine

Uses
This medication is used to treat several mental/mood disorders (e.g., schizophrenia, mania, restlessness/nervousness, behavior problems), nausea/vomiting, hiccups, and a certain liver problem (acute porphyria). For nervousness, it is generally used when other medications cannot be taken. Chlorpromazine can improve the symptoms of schizophrenia, mania, and mood, making it easier to function in everyday life. Chlorpromazine is part of a class of drugs called phenothiazines. It works by affecting the balance of certain chemicals in the brain.
Notes

Do not share this medication with others.Do not miss medical and laboratory test appointments.Laboratory and/or medical tests (e.g., liver function, blood counts, eye exams) should be performed periodically to monitor your progress or check for side effects.
Consult your doctor for more details.

Storage

Store tablets at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture.
The syrup should be stored below 77 degrees F (25 degrees C).
Do not store in the bathroom.
Keep all medicines away from children and pets.

Overdose

Symptoms of overdose may include: severe drowsiness/deep sleep, loss of consciousness, agitation, restlessness, seizures, irregular heartbeat.

How To Use

Take this medication by mouth with or without food, usually 2-4 times daily or as directed by your doctor.
Take the prescribed number of tablets.
Dosage is based on your medical condition, age, weight, and response to therapy.
Your doctor may start you at a low dose and gradually increase your dose over several weeks.
Follow your doctor's instructions carefully.This medication does not work right away for some conditions.
It may take up to 2-3 weeks before you experience the full benefits.Take this medication regularly in order to get the most benefit from it.
To help you remember, take it at the same times each day.Do not stop taking this medication without consulting your doctor.
Some conditions may become worse when the drug is suddenly stopped.
Your dose may need to be gradually decreased.Inform your doctor if your condition persists or worsens.

Side Effects

Drowsiness, dizziness, dry mouth, blurred vision, tiredness, nausea, constipation, and trouble sleeping may occur.
You may also be more sensitive to sunburn and less able to tolerate heat/strenuous exercise (see Precautions section).
If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
Many people using this medication for longer time periods may develop serious side effects, but with frequent visits to your doctor, this risk can be minimized.Tell your doctor immediately if any of these unlikely but serious side effects occur: feelings of restlessness/agitation/jitteriness, mask-like facial expression, shuffling walk, drooling, uncontrolled shaking of the hands, twitching in the face, muscle spasm/weakness, trouble swallowing, uncontrollable movements of the mouth/face/hands, unusual mental/mood changes (e.g., depression, worsening of psychosis), unusual dreams, trouble urinating, severe constipation, severe stomach/abdominal pain, unexplained weight gain, swelling of the feet/ankles, nipple discharge, swollen/tender breasts, changes in menstrual flow, decreased sexual ability, fast/pounding heartbeat with headache, severe dizziness, butterfly-shaped facial rash, joint/muscle pain, confusion, darkening of skin color, vision changes, fainting.For males, in the very unlikely event you have a painful, prolonged erection (lasting more than 4 hours), stop using this drug and seek immediate medical attention or permanent problems could occur.Tell your doctor immediately if any of these rare but very serious side effects occur: fever with persistent sore throat/cough/chills, yellowing of the eyes/skin, dark urine, severe stomach/abdominal pain, unusual bleeding/bruising, chest pain, seizures, confusion, rigid/unresponsive state, severe tiredness, breathing problems, pale skin.This drug may infrequently cause a serious (sometimes fatal) nervous system problem (neuroleptic malignant syndrome).
Seek immediate medical attention if you notice any of the following rare but very serious side effects: fever, rigid muscles, increased sweating, fast heartbeat, mental/mood changes, change in the amount of urine.A very serious allergic reaction to this drug is rare.
However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Before taking chlorpromazine, tell your doctor or pharmacist if you are allergic to it; or to other phenothiazines (e.g., chlorpromazine, promethazine); or if you have any other allergies.This medication should not be used if you have certain medical conditions.
Before using this medicine, consult your doctor or pharmacist if you have: intoxication with alcohol/narcotics/other drugs that cause drowsiness.This medication should not be used in a patient who is unconscious.Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems, kidney problems, certain heart problems (e.g., angina), heart rhythm problems, very high or low blood pressure, blockage of intestines, eye problems (e.g., glaucoma), seizures, enlarged prostate, breathing problems (e.g., severe asthma, emphysema, lung infections), blood disorders (e.g., low white or red blood cells), low blood calcium levels, low body water (dehydration), breast cancer.This drug may make you dizzy or drowsy or cause blurred vision.
Use caution while driving, using machinery, or doing any activity that requires alertness and clear vision.
Avoid alcoholic beverages.To minimize dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.Before having surgery or imaging procedures (e.g., certain X-rays, CT scan) requiring the use of dye, tell your doctor or dentist that you are using this medication.This medication may make you more sensitive to the sun.
Avoid prolonged sun exposure, tanning booths, and sunlamps.
Wear sunblock (SPF 30 or greater) and a hat when outdoors.Caution is advised during hot weather because chlorpromazine may decrease your ability to sweat, leading to fever or heatstroke.
Drink plenty of fluids and dress lightly.
Avoid strenuous exercise in hot weather.
If you become overheated, promptly seek cooler shelter and/or stop exercising.
Seek immediate medical attention if your body temperature is above normal or if you have mental/mood changes, headache, or dizziness.Facial/muscle twitching and uncontrollable movements (tardive dyskinesia) may occur with this medication and may be permanent.
It is not known which people are at risk of having this effect become irreversible.
The risk may be greater with large doses and prolonged use of this medication.
Discuss ways to minimize this risk with your doctor.Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug, especially drowsiness, dizziness (which may increase the risk of falls), and the development of uncontrolled movements (e.g., tardive dyskinesia).Caution is advised when using this drug in children because they may be more sensitive to the effects of the drug.During pregnancy, this medication should be used only when clearly needed.
Infants exposed to this medication during pregnancy may develop liver problems or muscle/movement problems.
Discuss the risks and benefits with your doctor.This medication passes into breast milk.
Therefore, breast-feeding while using this medication is not recommended.
Consult your doctor before breast-feeding.

Missed Dose

If you miss a dose, take it as soon as you remember.
If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
Do not double the dose to catch up.

Drug Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: metrizamide, pergolide, cabergoline, sibutramine, drugs that may affect the heart rhythm (QTc prolonging drugs such as cisapride, pimozide, ziprasidone, amiodarone, droperidol, ranolazine, halofantrine, bepridil, disopyramide).If you are currently using any of these medications, tell your doctor or pharmacist before starting chlorpromazine.Other drugs besides chlorpromazine and those listed above that may affect the heart rhythm (QTc prolongation in the EKG) include dofetilide, quinidine, sotalol, procainamide, and erythromycin, among others.
QTc prolongation can infrequently result in a serious (rarely fatal) irregular heartbeat.
Consult your doctor or pharmacist for more details and for instructions on how you may minimize the risk of this effect.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: alpha blockers (e.g., prazosin), blood thinners (e.g., warfarin), propranolol, guanethidine, guanadrel, lithium, phenytoin, certain "water pills"/diuretics (e.g., hydrochlorothiazide, chlorthalidone).Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., phenobarbital), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), other psychiatric medicines (e.g., risperidone, trazodone).Also report the use of the following drugs which might increase your risk of a seizure when combined with chlorpromazine such as bupropion; isoniazid (INH); other phenothiazines (e.g., thioridazine); theophylline; tramadol; and tricyclic antidepressants (e.g., amitriptyline) among others.Consult your doctor or pharmacist for details.This drug may interfere with some laboratory tests (e.g.
certain pregnancy tests).
Make sure laboratory technicians and all your doctors know you use this drug.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.