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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Itraconazole Uses Itraconazole injection is an azole antifungal used to treat a variety of fungal infections. Notes Do not share this medication with others.Laboratory and/or medical tests (e.g., liver function tests, potassium levels) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.This medication has been prescribed for your current condition only. Do not use it later for another infection unless told to do so by your doctor. A different medication may be necessary in that case. Storage Store the kit at room temperature at or below 77 degrees F (25 degrees C) away from light. Do not freeze.Store the diluted product at room temperature between 59-77 degrees F (15-25 degrees C) or in the refrigerator between 36-46 degrees F (2-8 degrees C) away from light. The diluted product should be used within 48 hours and can be exposed to normal room light when in use. Keep all medicines away from children and pets. How To Use This medication is given by injection into a vein over 1 hour by a health care professional. Learn all preparation and usage instructions for this product. Follow all instructions for proper mixing and dilution with the correct IV fluid. Use only the IV fluid (normal saline) provided with the medication. Before using this product, check it visually for particles or discoloration. If either is present, do not use the liquid. If you have questions about the use of this medication, consult the doctor or pharmacist.This medication is usually given twice daily for 4 doses, then once daily or as directed by your doctor. The length of treatment is based on your medical condition and response to treatment. You may eventually be switched over to itraconazole taken by mouth. Use this medication exactly as prescribed by your doctor.This medication works best when the amount of medicine in your body is kept at a constant level. Therefore, use this drug at evenly spaced intervals.Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear. Stopping the medication too early may result in a return of the infection.Learn how to store and discard needles and medical supplies safely. Tell your doctor if your condition persists or worsens. Side Effects See also Warning section.Nausea, vomiting, or diarrhea may occur. If any of these effects persist or worsen, tell your doctor promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: pain/swelling at injection site, new signs of infection (e.g., fever, persistent sore throat), irregular heartbeat, muscle cramps, numbness/tingling of the hands/feet.Itraconazole has rarely caused very serious (possibly fatal) liver disease. If you notice any of the following rare but very serious side effects, stop taking itraconazole and tell your doctor immediately: dark urine, yellowing eyes/skin, persistent nausea/vomiting, stomach/abdominal pain.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist. Precautions Before using itraconazole, tell your doctor or pharmacist if you are allergic to it; or to other azole antifungals (e.g., ketoconazole); or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease (or history of liver disease with other drugs), heart disease (e.g., coronary artery disease, heart valve disease, congestive heart failure), severe lung disease (e.g., chronic obstructive pulmonary disease-COPD).During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.Itraconazole passes into breast milk. Consult your doctor before breast-feeding. Missed Dose If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. Drug Interactions See also Warning section.Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: alfuzosin, certain benzodiazepines (e.g., midazolam taken by mouth, alprazolam, triazolam, estazolam), certain "statin" drugs (e.g., lovastatin, simvastatin), conivaptan, eletriptan, eplerenone, ergot alkaloids (e.g., ergotamine, dihydroergotamine), ivabradine, ranolazine, vardenafil.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting itraconazole.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: amiodarone, calcium channel blockers (e.g., verapamil, nifedipine), drugs affecting liver enzymes that remove itraconazole from your body (such as macrolide antibiotics including erythromycin; cimetidine; isoniazid; rifamycins including rifabutin; nevirapine; certain anti-seizure medicines including carbamazepine; phenytoin).This drug can slow down the removal of other drugs from your body by affecting certain liver enzymes. These affected drugs include certain antiarrhythmic medications (e.g., disopyramide, digoxin), certain chemotherapy drugs (e.g., busulfan, docetaxel, vinblastine), certain benzodiazepines (e.g., diazepam, injectable midazolam), certain immunosuppressants (e.g., tacrolimus, cyclosporine, sirolimus), certain "statin" drugs (e.g., atorvastatin), HIV protease inhibitors (e.g., indinavir, ritonavir, saquinavir), certain anti-diabetic drugs (e.g., hypoglycemics taken by mouth such as glyburide), halofantrine, alfentanil, fentanyl, solifenacin, buspirone, repaglinide, certain glucocorticosteroids (e.g., dexamethasone, budesonide), certain drugs for male sexual function problems (e.g., sildenafil, tadalafil), trimetrexate, aripiprazole, trazodone, tolterodine, "blood thinners" (e.g., warfarin), sunitinib, and cilostazol.Do not infuse itraconazole together in the same line or bag with other drugs.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.