IndapamideOral - Drug Information and Side Effects on Drug3k.com


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Overview

Photos

How To Use

Side Effects

Precautions

Missed Dose

Drug Interactions

Indapamide

Uses
This medication is used alone or in combination with other medications to treat high blood pressure (hypertension). Indapamide is also used to help the body get rid of extra salt and water that builds up with chronic heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Decreasing salt and water helps to decrease the swelling and breathing problems from chronic heart failure and increases your ability to exercise.Indapamide is a water pill (diuretic) that increases the amount of urine you make. Getting rid of extra water and salt probably helps to relax the blood vessels so that blood can flow more easily. These effects help to lower blood pressure and decrease the amount of work the heart must do to pump blood.
Notes

Do not share this medication with others.
Lifestyle changes such as stress reduction programs, exercise, and dietary changes may increase the effectiveness of this medicine.
Talk to your doctor or pharmacist about lifestyle changes that might benefit you.Laboratory and/or medical tests (e.g., white blood cell count, blood sodium and potassium levels, kidney function, liver function) should be performed from time to time to monitor your progress or check for side effects.
Consult your doctor for more details.Have your blood pressure checked regularly while taking this medication.
Learn how to monitor your own blood pressure, and share the readings with your doctor.

Storage

Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture.
Do not store in the bathroom.
Keep all medicines away from children and pets.

How To Use

Take this medication by mouth with or without food, usually once daily in the morning or as directed by your doctor.
It is best to take this medication early in the day (before 10 AM) to avoid having to get up during the night to urinate.
Consult your doctor or pharmacist if you have questions about your dosing schedule.The dosage is based on medical condition and response to therapy.
If you have severe liver or kidney problems, your dosage may need to be adjusted.Take indapamide at least 4 hours before or after certain cholesterol-lowering medications (bile acid-binding resin drugs such as colestipol/cholestyramine).
These products can react with indapamide, preventing its full absorption.Use this medication regularly in order to get the most benefit from it.
To help you remember, take it at the same time each day.
It is important to continue taking this medication even if you feel well.
Most people with high blood pressure do not feel sick.
It may take up to several weeks before the full benefit of this drug takes effect.Do not stop taking this medication without first consulting your doctor.
Some conditions may become worse when the drug is abruptly stopped.
Your dose may need to be gradually decreased.Inform your doctor if your condition worsens (e.g., your routine blood pressure readings increase or you have more swelling or feel more shortness of breath).

Side Effects

Dizziness, lightheadedness, and tiredness may occur as your body adjusts to the medication.
Headache, numbness/tingling of the hands/feet, and mental/mood changes (e.g., nervousness, anxiety, irritability, agitation) may also occur.
You may also experience decreased sexual ability/interest or increased sensitivity to the sun.
If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Indapamide may cause too much body water and salts to be lost (dehydration).
Tell your doctor immediately if you have any of these unlikely but serious symptoms of dehydration: very dry mouth, thirst, muscle cramps, weakness, fast heartbeat, nausea, vomiting, severe dizziness, confusion, unusual decrease in the amount of urine, fainting, seizures.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects.
Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: blurred vision, diarrhea, constipation, stomach pain, loss of appetite, weight loss, dizziness when standing, flushing, irregular heartbeat.This drug may rarely cause serious liver or pancreas problems.
Tell your doctor immediately if you notice any of the following rare but very serious side effects: yellowing of the eyes/skin, dark urine, severe stomach/abdominal pain, persistent tiredness, persistent nausea/vomiting.Tell your doctor immediately if any of these rare but very serious side effects occur: signs of infection (e.g., fever, chills, persistent sore throat), easy bruising/bleeding, new/severe tiredness, breathing problems, weakness, bluish fingernails/lips, pale skin.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.
Symptoms of a serious allergic reaction may include: rash, itching, swelling of any part of the face/neck, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Before taking this product, tell your doctor or pharmacist if you are allergic to indapamide; or to thiazide diuretics (e.g., polythiazide, hydrochlorothiazide); or to sulfa medications; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
Before using this medicine, consult your doctor or pharmacist if you have: an inability to make urine.Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (e.g., congestive heart failure), kidney problems (e.g., kidney dialysis), liver disease, gout, diabetes, untreated mineral imbalance (e.g., high calcium, low potassium, low magnesium), loss of too much body water (dehydration), collagen vascular disease (e.g., lupus, scleroderma), recent nerve surgery (e.g., sympathectomy).This drug may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery.
Limit alcoholic beverages.To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.Drink plenty of fluids while taking this medication to help prevent dizziness.
Too much sweating, diarrhea or vomiting may cause you to feel lightheaded.
Avoid heavy exercise.
Report prolonged diarrhea or vomiting to your doctor.Before having surgery, tell your doctor or dentist that you are taking this medication.This medication may make you more sensitive to the sun.
Avoid prolonged sun exposure, tanning booths, and sunlamps.
Use a sunscreen and wear protective clothing when outdoors.This product may decrease your potassium levels.
Before using potassium supplements or salt substitutes containing potassium, consult your doctor or pharmacist.
If you have diabetes, this product may increase your blood sugar levels.
Check your blood sugar levels regularly as directed by your doctor.
Tell your doctor immediately if you have symptoms of high blood sugar, such as increased thirst and urination.
Your anti-diabetic medication or diet may need to be adjusted.Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially dizziness.This medication should be used only when clearly needed during pregnancy.
Discuss the risks and benefits with your doctor.It is not known if indapamide passes into breast milk.
Since this drug could have undesirable effects on a nursing infant, breast-feeding while using this medication is not recommended.
Consult your doctor before breast-feeding.

Missed Dose

If you miss a dose, take it as soon as you remember.
If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
Do not double the dose to catch up.

Drug Interactions

See also Precautions section.Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it.
Do not start, stop or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: disopyramide, cisapride, bepridil.Other drugs besides those listed above which may affect the heart rhythm (QTc prolongation in the EKG) include amiodarone, dofetilide, pimozide, guanidine, sotalol, procainamide, and erythromycin, among others.
QTc prolongation can infrequently result in serious (rarely fatal) irregular heartbeats.
Consult your doctor or pharmacist for more details, and for instructions on how you may minimize the risk of this effect.Before using this medication, tell all your doctors or pharmacists of all prescription and nonprescription/herbal products you may use, especially of: drugs for diabetes (e.g., glyburide, insulin), aspirin, certain nonsteroidal anti-inflammatory drugs-NSAIDs (e.g., celecoxib, ibuprofen, indomethacin), diazoxide, digoxin, lithium, probenecid, drugs that may decrease your potassium level (e.g., amphotericin B, corticotropin, corticosteroids including prednisone), drugs whose removal from the body is affected by the acid level of urine (e.g., amphetamine, methenamine, quinidine).Check the labels on all your medicines (e.g., cough-and-cold products, diet aids, nonsteroidal anti-inflammatory drugs-NSAIDs for pain/fever reduction) because they may contain ingredients that could increase your blood pressure or cause a fast heartbeat (e.g., pseudoephedrine, phenylephrine, chlorpheniramine, diphenhydramine, clemastine, ibuprofen, naproxen).
Ask your pharmacist about the safe use of those products.This product can affect the results of certain lab tests (e.g., parathyroid, certain tests that measure digoxin drug levels).
Make sure laboratory personnel and all your doctors know you use this drug.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.