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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Imipramine Tofranil, Tofranil-PM Uses Treats depression. May also be used to treat bedwetting in children. This medicine is a tricyclic antidepressant. Storage Store this medicine in a tightly-closed container, away from heat, moisture, and direct light. Keep all medicine out of the reach of children. How To Use APPEARANCE: Capsule, Tablet. Your doctor will tell you how much medicine to take and how often. Take with or without food. Do not crush or chew the capsules. You may open the capsules and mix the medicine beads with soft food (pudding or applesauce). Swallow the mixture without chewing. If you are taking this drug for depression, it may take 2 to 3 weeks before you start to feel better. Do not stop taking this medicine suddenly. You may need to take smaller and smaller doses before completely stopping. This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one. Your doctor might ask you to sign some forms to show that you understand this information. Side Effects Call your doctor right away if you notice any of these side effects: Fainting Fast, pounding or irregular heartbeat Unexplained fever or sore throat Skin rash Trouble going to the bathroom (urinating) Precautions You should not use this medicine if you have ever had an allergic reaction to it or to related medicine such as Elavil®, Aventyl®, Tegretol®, Ludiomil®, or Desyrel®. You should not take imipramine if you have had a recent heart attack or have taken an MAO inhibitor such as Nardil®, Marplan®, or Parnate® in the past 14 days. Missed Dose Take the missed dose as soon as possible. If it is almost time for your next dose, wait until then to take your medicine and skip the missed dose. If you take one dose a day at bedtime, you should not use the missed dose the next morning. Wait until your next regular bedtime dose. You should not use two doses at the same time. Drug Interactions This medicine is harmful to use during pregnancy. It may cause birth defects. Using this medicine while breastfeeding may cause drowsiness or other side effects in the nursing baby. Tell your doctor if you have ever had glaucoma, trouble urinating, stomach problems, seizures, heart disease, liver disease, kidney disease, or thyroid disease. For some children and teenagers, this medicine can increase thoughts of suicide. All of the warnings in this leaflet are true for a child or teenager who is using this medicine. Tell your doctor right away if you start to feel more depressed. Also tell your doctor right away if you have thoughts about hurting yourself. Report any unusual thoughts or behaviors that trouble you, especially if they are new or get worse quickly. Make sure your caregiver knows if you have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. Also tell your doctor if you have sudden or strong feelings, such as feeling nervous, angry, restless, violent, or scared. Let your doctor know if you or anyone in your family has bipolar disorder (manic-depressive) or has tried to commit suicide. Do not give this medicine to a child unless directed to do so by the child's doctor. This medicine may cause dizziness and vision changes. Avoid driving a car or operating machinery. This medicine may make your skin more sensitive to sunlight. Use a sunscreen when outdoors. Avoid sunlamps and tanning beds.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.