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Glyburide is an anti-diabetic drug (sulfonylurea-type) used along with a proper diet and exercise program to control high blood sugar. It is used in patients with type 2 diabetes (non-insulin-dependent diabetes). It works by stimulating the release of your body s natural insulin. Effectively controlling high blood sugar helps prevent heart disease, strokes, kidney disease, blindness, and circulation problems, as well as sexual function problems (impotence).
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Micronase, Diabeta
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| Overview |
Photos |
How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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Glyburide - Oral
Micronase, Diabeta
Uses
Glyburide is an anti-diabetic drug (sulfonylurea-type) used along with a proper diet and exercise program to control high blood sugar. It is used in patients with type 2 diabetes (non-insulin-dependent diabetes). It works by stimulating the release of your body s natural insulin. Effectively controlling high blood sugar helps prevent heart disease, strokes, kidney disease, blindness, and circulation problems, as well as sexual function problems (impotence).
Storage
- Store at room temperature away from light and moisture.
- Storage temperature ranges differ according to different manufacturers, so consult your pharmacist for more information.
- Do not store in the bathroom.
- Keep all medicines away from children and pets.
Overdose
- If overdose is suspected, contact your local poison control center or emergency room immediately.
- Symptoms of overdose may include: shakiness, rapid heartbeat, sweating, loss of consciousness.
Photos
Novopharm: NOVO-GLYBURIDE Markings |
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Picture of GLYBURIDE-METFORMIN 5/500 |
GLYBURIDE-METFORMIN 2.5-500 MG |
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How To Use
- Take Glyburide by mouth with breakfast or the first main meal, usually once daily; or use as directed by your doctor.
- Some patients, especially those taking higher doses, may be directed to take Glyburide twice a day.
- The dosage is based on your medical condition and response to therapy.
- Use Glyburide regularly in order to get the most benefit from it.
- To help you remember, use it at the same time(s) each day.
- Monitor blood glucose levels on a regular basis.
Side Effects
- Nausea, heartburn, stomach fullness, and weight gain may occur.
- If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
- Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: persistent sore throat or fever, easy bleeding or bruising, stomach pain, yellowing eyes or skin, dark urine, unusual tiredness or weakness, unusual or sudden weight gain, mental/mood changes, swelling of the hands or feet, seizures.
- Glyburide can cause low blood sugar (hypoglycemia).
- This effect may occur if you do not consume enough calories (from food, juices, fruit, etc.).
- The symptoms include chills, cold sweat, blurred vision, dizziness, drowsiness, shaking, rapid heart rate, weakness, headache, fainting, tingling of the hands or feet, or hunger.
- It is a good habit to carry glucose tablets or gel to treat low blood sugar.
- If you are in a situation where you don t have these reliable forms of glucose, eat a quick source of sugar such as table sugar, honey, or candy, or drink a glass of orange juice or non-diet soda to quickly raise your blood sugar level.
- Tell your doctor immediately about the reaction.
- To help prevent hypoglycemia, eat meals on a regular schedule and do not skip meals.
- Symptoms of high blood sugar (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, or fruity breath odor.
- If these symptoms occur, tell your doctor immediately.
- Your medication dosage may need to be increased.
- An allergic reaction to Glyburide is unlikely, but seek immediate medical attention if it occurs.
- Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing.
- If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Glyburide should not be used if you have certain medical conditions.
- Before using Glyburide, consult your doctor or pharmacist if you have: metabolic conditions (e.g., diabetic ketoacidosis).
- Before using Glyburide, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, thyroid disease, certain hormonal conditions (adrenal/pituitary insufficiency, SIADH-syndrome of inappropriate secretion of antidiuretic hormone), electrolyte imbalance (hyponatremia), high blood pressure, any allergies.
- You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar levels; use caution engaging in activities requiring alertness such as driving or using machinery.
- Limit alcohol while taking Glyburide because it can increase the risk of developing hypoglycemia.
- Rarely, alcohol can interact with glyburide and cause a serious reaction (disulfiram-like reaction) with symptoms such as facial flushing, nausea, vomiting, dizziness, or stomach pain.
- Consult your doctor or pharmacist about the safe use of alcohol.
- During times of stress, such as fever, infection, injury or surgery, it may be more difficult to control your blood sugar.
- Consult your doctor, as a change in your medication may be required.
- Glyburide may make you more sensitive to the sun.
- Avoid prolonged sun exposure, tanning booths or sunlamps.
- Use a sunscreen and wear protective clothing when outdoors.
- Caution is advised when using Glyburide in the elderly because they may be more sensitive to the effects of Glyburide, especially hypoglycemia.
- Glyburide should be used only when clearly needed during pregnancy.
- It is not recommended for use for at least 2 weeks before delivery due to the potential for fetal harm.
- Insulin may be preferred during pregnancy.
- Discuss the risks and benefits with your doctor.
- Based on information from related drugs, Glyburide may pass into breast milk.
- Therefore, breast-feeding while using Glyburide is not recommended.
Missed Dose
- If you miss a dose, use it as soon as you remember.
- If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
- Do not double the dose to catch up.
Drug Interactions
- Glyburide should not be used with the following medications because very serious interactions may occur: bosentan.
- If you are currently using any of these medications, tell your doctor or pharmacist before starting glyburide.
- Before using Glyburide, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: other diabetes drugs (e.g., insulin, metformin), aspirin or aspirin-like drugs (e.g., salicylates, NSAIDs such as ibuprofen, phenylbutazone), azole antifungals (e.g., fluconazole), beta-blockers -- including glaucoma eye drops (e.g., propranolol, timolol, metoprolol), birth control pills, "blood thinners (e.g., warfarin), calcium channel blockers (e.g., diltiazem), chloramphenicol, clofibrate, corticosteroids (e.g., prednisone), decongestants (e.g., pseudoephedrine), diazoxide, diet pills, epinephrine, estrogens, isoniazid, MAO inhibitors (e.g., furazolidone, linezolid, moclobemide, phenelzine procarbazine, selegiline, isocarboxazid, tranylcypromine), niacin, phenothiazines (e.g., promethazine), phenytoin, probenecid, quinolone antibiotics (e.g., ciprofloxacin), rifampin, sulfonamides (e.g., sulfa antibiotics), thyroid drugs, water pills (diuretics such as hydrochlorothiazide, furosemide), fenugreek, ginseng.
- Do not start or stop any medicine without doctor or pharmacist approval.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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