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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Gliadel Wafer Impl Uses This medication is used with brain surgery and radiation to treat a certain type of brain tumor ( malignant glioma). It is also used with surgery to treat a type of malignant glioma (glioblastoma multiforme) that comes back.Carmustine works by stopping the growth of tumor cells. It helps to kill any leftover tumor cells that are not taken out by the surgery. Polifeprosan 20 works by controlling the release of carmustine into the area where the brain tumor was taken out. Notes Keep all regular medical and laboratory appointments.Laboratory and/or medical tests (e.g., wound exams) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. Storage Store in a freezer at or below -4 degrees F (-20 degrees C). Unopened foil pouches may be kept at room temperature for up to 6 hours. Consult your pharmacist for details. Keep all medicines away from children and pets. How To Use This medication is placed by a surgeon during brain surgery into the area where the brain tumor was taken out. The implant will dissolve slowly, releasing the medication to the surrounding area. Follow all your doctor's instructions on what to do before and after surgery.The number of implants placed is based on the size of the area to cover. The maximum recommended dose is 8 implants placed at each surgery. Side Effects Constipation, stomach/abdominal/back pain, nausea, or vomiting may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.People using this medication may have serious side effects. However, your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.Tell your doctor immediately if any of these unlikely but serious side effects occur: swelling/redness/warmth at surgery site, wound at surgery site that is opening or not healing properly, signs of an infection (e.g., fever), chest pain, mental/mood changes (e.g., depression, anxiety).Seek immediate medical attention if any of these unlikely but very serious side effects occur: seizures, severe headache, extreme tiredness/weakness, confusion, weakness on one side of the body, slurred speech, stiff neck, fainting.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice any other effects not listed above, contact your doctor or pharmacist. Precautions Before receiving carmustine/polifeprosan 20, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history.This medication is not recommended for use during pregnancy. Consult your doctor for more details. If you become pregnant or think you may be pregnant, tell your doctor immediately.It is not known whether this drug passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding. Missed Dose Not applicable. Drug Interactions Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use.

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