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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Papain/urea Accuzyme, AllanZyme, Ethezyme 650, Allanzyme 650 Ointment, Ethezyme, Kovia, Ethezyme 830, Gladase, Ethezyme 830 Papain Uses Treats burns, bedsores, wounds from surgery, or skin ulcers. Storage Store the medicine in a cool place. Do not freeze. Keep the container opening covered and clean when you are not using it. Store the spray upright. Ask your pharmacist, doctor, or health caregiver about the best way to dispose of the used medicine container and any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed. Keep all medicine away from children and never share your medicine with anyone. How To Use APPEARANCE: Spray, Ointment. Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to. This medicine is for use on the skin only. Do not get it in your eyes, nose, or mouth. Do not use it on skin areas that have cuts or scrapes. If it does get on these areas, rinse it off right away. Wash your hands with soap and water before and after using this medicine. Clean your skin wound with saline or other cleanser recommended by your doctor. Before using a new spray bottle, prime the pump by holding the spray upright directly over the wound, and pumping 10 to 14 times. To use the spray form of this medicine, hold the bottle about 1 to 2 inches from your wound. Use even, firm, and equal pressure each time you pump the bottle to spray the medicine onto your wound. Completely cover the wound with this medicine. After applying the medicine, cover the skin area with a bandage or other dressing recommended by your doctor. To use the ointment form of this medicine, apply it directly to the skin wound. After applying the medicine, cover the skin area with a bandage or other dressing recommended by your doctor. For best results, cleanse or irrigate your skin wound each time you change your bandages, even if you do not apply papain/urea each time. Side Effects Call your doctor right away if you notice any of these side effects: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. Precautions You should not use this medicine if you have had an allergic reaction to papain or urea. Missed Dose If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose. Drug Interactions Make sure your doctor knows if you are pregnant or breast feeding. Do not use this medicine for a skin problem that has not been checked by your doctor. If your symptoms do not improve or if they get worse, call your doctor.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.