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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Gatifloxacin Uses Gatifloxacin is used to treat a variety of bacterial infections. This medication belongs to a class of drugs called quinolone antibiotics. It works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness. Notes Do not share this medication with others.This medication has been prescribed for your current condition only. Do not use it later for another infection unless told to do so by your doctor. A different medication may be necessary in that case.Laboratory and/or medical tests (e.g., kidney function, complete blood count, blood glucose) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. Storage Unless otherwise directed by your pharmacist, store the medication at room temperature at 77 degrees F (25 degrees C). Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Check with your pharmacist for how long you can use this medication after it is mixed. Keep all medicines away from children and pets. How To Use This medication is given by injection into a vein, usually once daily or as directed by your doctor. Gatifloxacin must be mixed with the proper IV fluids. This product normally appears light-yellow to greenish-yellow. Before using this product, check it visually for particles or discoloration. If either is present, do not use the liquid. This medication should be infused slowly over 1 hour. If you have questions about the use of this medication, consult your pharmacist.The dosage and length of treatment is based on your medical condition and response to treatment.Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, use this drug at evenly spaced intervals (e.g., every 24 hours).Continue to use this medication for the full time prescribed, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.Inform your doctor if your condition persists or worsens. Side Effects Nausea, diarrhea, dizziness, lightheadedness, headache, or trouble sleeping may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: shaking (tremors), mental/mood changes (e.g., anxiety, confusion, hallucinations, depression, rare thoughts of suicide), redness/swelling/pain at the injection site.Tell your doctor immediately if any of these rare but very serious side effects occur: seizures, severe/persistent headache, vision changes, ringing in the ears, unusual bruising/bleeding, signs of a new infection (e.g., new/persistent fever, persistent sore throat), unusual change in the amount of urine, fainting, fast/irregular heartbeat, signs of liver problems (e.g., unusual tiredness, stomach/abdominal pain, persistent nausea/vomiting, yellowing eyes/skin, dark urine).Gatifloxacin may rarely cause serious nerve problems that may be reversible if identified and treated early. Seek immediate medical attention if you develop any of the following symptoms: pain/numbness/burning/tingling/weakness in any part of the body, changes in how you sense touch/pain/temperature/body position/vibration.This medication may rarely cause tendon damage (e.g., tendonitis, tendon rupture) during or after treatment. Stop exercising, rest, and seek immediate medical attention if you develop joint/muscle/tendon pain or swelling.This medication may rarely cause a severe intestinal condition (pseudomembranous colitis) due to a type of resistant bacteria. This condition may occur during treatment or weeks after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have any of the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching, swelling, severe dizziness, trouble breathing, chest pain.If you notice other effects not listed above, contact your doctor or pharmacist. Precautions Before using gatifloxacin, tell your doctor or pharmacist if you are allergic to it; or to other quinolone antibiotics (e.g., ciprofloxacin, levofloxacin); or if you have any other allergies.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: personal or family history of a certain abnormal heart rhythm (long QT interval or QTc prolongation), untreated low blood potassium level (hypokalemia), diabetes.Before using this medication, tell your doctor or pharmacist your medical history, especially of: seizure disorder, conditions that increase your risk of seizures (e.g., brain/head injury, brain tumors, cerebral atherosclerosis), nervous system disorders (e.g., peripheral neuropathy), kidney disease, joint/tendon problems (e.g., tendonitis, bursitis), heart problems (e.g., bradycardia, other abnormal heart rhythms, recent heart attack).This medication may rarely cause serious changes in blood glucose levels, especially if you have diabetes. These changes may also occur in people who do not know they have diabetes or who are at high risk for diabetes. Watch for symptoms of high blood sugar including increased thirst and urination. Also watch for symptoms of low blood sugar such as nervousness, shaking, sweating, fast heartbeat, or hunger. Follow your doctor's instructions to treat your low blood sugar level (e.g., take glucose tablets or gel; eat a quick source of sugar such as table sugar, honey, or candy; drink a glass of orange juice or non-diet soda). Seek immediate medical attention if you experience symptoms of high or low blood sugar while taking this medication. Monitor your blood glucose levels as directed by your doctor.This drug may make you dizzy or lightheaded. Use caution while driving, using machinery, or taking part in any activity that requires alertness. Limit alcoholic beverages.Though gatifloxacin has not been reported to make your skin more sensitive to the sun, similar drugs may cause this effect. Therefore, as a precaution, avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors. Tell your doctor immediately if you develop any sunburn-like skin reactions.Caution is advised when using this medication in children younger than 18 years of age because they may be at greater risk for joint/tendon problems. Discuss the risks and benefits with the doctor.Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, the elderly may be more sensitive to its side effects (e.g., blood sugar or tendon problems), especially if they are also taking corticosteroids (e.g., prednisone, hydrocortisone).During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding. Missed Dose If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. Drug Interactions Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: certain drugs that affect the heart rhythm (antiarrhythmics that may cause QTc prolongation such as amiodarone, dofetilide, quinidine, procainamide, sotalol).If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting gatifloxacin.Other drugs besides gatifloxacin and those listed above that may affect the heart rhythm (QTc prolongation in the EKG) include cisapride, certain macrolide antibiotics (e.g., erythromycin, clarithromycin), and certain antipsychotic medications (e.g., pimozide, thioridazine, ziprasidone), among others. QTc prolongation can infrequently result in serious (rarely fatal) irregular heartbeat. Ask your doctor or pharmacist for more details, and for instructions on how you may reduce the risk of this effect.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: live bacterial vaccines, corticosteroids (e.g., prednisone, hydrocortisone), drugs for diabetes (e.g., glyburide, insulin), digoxin, nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, naproxen), drugs that decrease potassium levels (e.g., certain "water pills"/diuretics such as furosemide, hydrochlorothiazide), probenecid, warfarin.Also report the use of drugs which might increase seizure risk when combined with gatifloxacin such as isoniazid (INH), phenothiazines (e.g., chlorpromazine), theophylline, or tricyclic antidepressants (e.g., amitriptyline), among others. Consult your doctor or pharmacist for details. Share and Enjoy!

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.