Fosinopril-HydrochlorothiazideOral - Drug Information and Side Effects on Drug3k.com


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Fosinopril-Hydrochlorothiazide images:

Overview

Photos

How To Use

Side Effects

Precautions

Missed Dose

Drug Interactions

Fosinopril-Hydrochlorothiazide

Uses
This medication is used with or without other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.This product contains two medications, fosinopril and hydrochlorothiazide. Fosinopril is called an ACE inhibitor and works by relaxing blood vessels so blood can flow more easily. Hydrochlorothiazide is called a water pill (diuretic) and causes your body to get rid of extra salt and water. This increases the amount of urine you make. Getting rid of extra water and salt probably also helps to relax the blood vessels so that blood can flow more easily. These medications are used together when one drug is not controlling your blood pressure.This drug may also be used to treat certain heart conditions (e.g., congestive heart failure).
Notes

Do not share this medication with others.
Lifestyle changes such as stress reduction programs, exercise, and dietary changes may increase the effectiveness of this medicine.
Talk to your doctor or pharmacist about lifestyle changes that might benefit you.Laboratory and/or medical tests (e.g., white blood cell count, blood sodium and potassium levels, kidney function, liver function) should be performed from time to time to monitor your progress or check for side effects.
Consult your doctor for more details.Check your blood pressure regularly while taking this medication, especially when you first start this drug or when your dose is changed.
Learn how to monitor your own blood pressure at home, and share the results with your doctor.

Storage

Store at a temperature of 77 degrees F (25 degrees C) away from light and moisture.
Brief storage from 59-86 degrees F (15-30 degrees C) is permitted.
Do not store in the bathroom.
Keep all medicines away from children and pets.

Overdose

Symptoms of overdose may include: severe dizziness.

How To Use

Take this medication by mouth with or without food, usually once daily or as directed by your doctor.
If you take this drug too close to bedtime, you may need to wake up to urinate.
Therefore, it is best to take this medication at least 4 hours before your bedtime.
Consult your doctor or pharmacist if you have questions about your dosing schedule.The dosage is based on your age, medical condition and response to therapy.
If you have severe liver or kidney problems, your dosage may need to be adjusted.If taken together with this drug, cholestyramine and colestipol can decrease the amount of this medication that is absorbed by your body.
If you are taking either of these drugs, separate them from this medication by at least 4 hours.Antacids may decrease your body's ability to absorb this product.
If you take antacids, take them 2 hours before or 2 hours after taking this medication.Use this medication regularly in order to get the most benefit from it.
To help you remember, take it at the same time each day.
It is important to continue taking this medication even if you feel well.
Most people with high blood pressure do not feel sick.
It may take up to several weeks before the full benefit of this drug takes effect.Do not stop taking this medication without first consulting your doctor.
Some conditions may become worse when the drug is abruptly stopped.
Your dose may need to be gradually decreased.Inform your doctor if your condition worsens (e.g., your routine blood pressure readings increase).

Side Effects

Dizziness or lightheadedness may occur as your body adjusts to the medication.
Nausea, tiredness, headache or dry cough may also occur.
You may also experience decreased sexual ability or increased sensitivity to the sun.
If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects.
Many people using this medication do not have serious side effects.The hydrochlorothiazide in this product may cause too much body water and salts to be lost (dehydration).
Tell your doctor immediately if you have any of these unlikely but serious symptoms of dehydration: very dry mouth, thirst, muscle cramps, weakness, fast heartbeat, nausea, vomiting, severe dizziness, confusion, unusual decrease in the amount of urine, fainting, seizures.Tell your doctor immediately if any of these unlikely but serious side effects occur: chest pain, swelling of the hands/feet, irregular heartbeat, numbness/tingling of the hands/feet, muscle/joint aches.This drug may rarely cause serious (possibly fatal) liver problems.
Tell your doctor immediately if you notice any of the following rare but very serious side effects: yellowing of the eyes/skin, dark urine, severe stomach/abdominal pain, persistent tiredness, persistent nausea/vomiting.Tell your doctor immediately if any of these rare but very serious side effects occur: signs of infection (e.g., fever, chills, persistent sore throat), easy bruising/bleeding, unusual change in the amount of urine (not including the normal increase in urine when you first start this drug).A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.
Symptoms of a serious allergic reaction may include: rash, itching, swelling of any part of the face/neck, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Before taking this product, tell your doctor or pharmacist if you are allergic to either fosinopril or hydrochlorothiazide; or to other ACE inhibitors (e.g., captopril, lisinopril); or to other thiazides (e.g., polythiazide); or to sulfa medications; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
Before using this medicine, consult your doctor or pharmacist if you have: a history of an allergic reaction that included swelling of the face/lips/tongue/throat (angioedema), an inability to make urine.Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (e.g., congestive heart failure), kidney problems (including renal artery stenosis and kidney dialysis), liver disease, gout, diabetes, untreated salt imbalance (e.g., high calcium, low potassium, low magnesium), loss of too much body water (dehydration), strokes, collagen vascular disease (e.g., lupus, scleroderma), recent nerve surgery (e.g., sympathectomy).This drug may make you dizzy or drowsy; use caution while engaging in activities requiring alertness such as driving or using machinery.
Limit alcoholic beverages.To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a seated or lying position.Drink plenty of fluids while taking this medication to help prevent dizziness.
Too much sweating, diarrhea or vomiting may cause you to feel lightheaded.
Avoid heavy exercise.
Report prolonged diarrhea or vomiting to your doctor.Before having surgery, tell your doctor or dentist that you are taking this medication.This medication may make you more sensitive to the sun.
Avoid prolonged sun exposure, tanning booths, and sunlamps.
Use a sunscreen and wear protective clothing when outdoors.This product may increase or decrease your potassium levels.
Before using potassium supplements or salt substitutes containing potassium, consult your doctor or pharmacist.
If you have diabetes, this product may increase your blood sugar levels.
Check your blood glucose levels regularly as directed by your doctor.
Tell your doctor immediately if you have symptoms of high blood sugar, such as increased thirst and urination.
Your anti-diabetic medication or diet may need to be adjusted.Caution is advised when using this drug in the elderly because they may be more sensitive to its effects, especially dizziness.This medication is not recommended for use during pregnancy due to the risk for harm to an unborn baby.
Consult your doctor for more details.
(See also Warning section.)The fosinopril and hydrochlorothiazide in this medication pass into breast milk and may have undesirable effects on a nursing infant.
Breast-feeding while using this medication is not recommended.
Consult your doctor before breast-feeding.

Missed Dose

If you miss a dose, take it as soon as you remember.
If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
Do not double the dose to catch up.

Drug Interactions

See also How to Use section.Also see Precautions.Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it.
Do not start, stop or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: cisapride, dofetilide.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: anesthesia drugs, barbiturates including phenobarbital, drugs affecting the bone marrow (e.g., azathioprine, trimethoprim-containing products), drugs for diabetes (e.g., glyburide, insulin), aspirin, certain nonsteroidal anti-inflammatory drugs-NSAIDs (e.g., celecoxib, ibuprofen, indomethacin), diazoxide, digoxin, guanethidine, lithium, mecamylamine, narcotic pain relievers (e.g., codeine, morphine), probenecid, tubocurarine, drugs that may increase your potassium level (e.g., drospirenone, potassium-sparing diuretics such as spironolactone, potassium supplements, salt substitutes), drugs that may decrease your potassium level (e.g., amphotericin B, corticotropin, corticosteroids including prednisone), drugs whose removal from the body is affected by the acid level of urine (e.g., amphetamine, methenamine, quinidine).A very serious reaction may occur if you are getting injections for bee/wasp sting allergy (desensitization) and are also taking fosinopril with hydrochlorothiazide.
Make sure all your doctors know which medicines you are using.Check the labels on all your medicines (e.g., cough-and-cold products, diet aids, nonsteroidal anti-inflammatory drugs-NSAIDs for pain/fever reduction) because they may contain ingredients that could increase your blood pressure or cause a fast heartbeat (e.g., pseudoephedrine, phenylephrine, chlorpheniramine, diphenhydramine, clemastine, ibuprofen, naproxen).
Ask your pharmacist about the safe use of those products.Some nonprescription medicines may also contain aspirin, which may decrease the effect of the fosinopril in this product.
Low-dose aspirin, as prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 milligrams per day) should be continued.
Consult your doctor or pharmacist for more details.This product can affect the results of certain lab tests (e.g., parathyroid, certain tests that measure digoxin drug levels, protein-bound iodide, tyramine and phentolamine tests).
Make sure laboratory personnel and your doctors know you use this drug.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.