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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Etanercept Enbrel Uses Treats rheumatoid arthritis in adults and children. Also treats psoriatic arthritis, ankylosing spondylitis, and plaque psoriasis. Storage If you store this medicine at home, keep it in the refrigerator. Do not freeze.Do not freeze. Once the powder medicine has been mixed with the liquid, this mixture must be stored in the refrigerator. You must use this mixture within 14 days. After 14 days, throw away any leftover mixture. Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets. Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. You will also need to throw away old medicine after the expiration date has passed. Keep all medicine away from children and never share your medicine with anyone. How To Use APPEARANCE: Injectable. This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin. A nurse or other trained health professional will give you this medicine. You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to. Use a new needle and syringe each time you inject your medicine. You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This powder medicine must be mixed with the liquid provided in your dose kit. Mix the medicine only when you are ready to use it. Do not shake the medicine after it has been mixed. Do not use if it is cloudy or has specks floating in it. If you are using one vial (bottle) for more than one dose of this medicine, use the "Mixing Date" stickers provided to write the date you mixed the medicine. Attach the sticker to the vial. Put the unused mixture in the refrigerator right away. Let the liquid medicine reach room temperature before you give yourself a shot (about 15 to 30 minutes). Do not remove the needle cover from the prefilled syringe while it is reaching room temperature. Side Effects Call your doctor right away if you notice any of these side effects: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. Chest pain, or coughing up blood. Fever, chills, cough, hoarseness, runny or stuffy nose, or a sore throat. Lightheadedness, fainting, seizure, or trouble thinking. Numbness or weakness in your arm or leg, or on one side of your body. Pain in your lower leg (calf). Shortness of breath, cold sweat, and bluish-colored skin. Sudden or severe headache, or problems with vision, speech, or walking. Sudden and severe stomach pain, nausea, and vomiting. Swelling in your hands, ankles, or feet. Unusual bleeding, bruising, pale skin, or weakness. Yellowing of your skin or the whites of your eyes. Precautions You should not use this medicine if you have had an allergic reaction to etanercept, or if you have sepsis (an infection in your blood). Missed Dose Call your doctor or pharmacist for instructions. Drug Interactions Make sure your doctor knows if you are pregnant or breastfeeding, or if you have diabetes, cancer, congestive heart failure, or a blood disorder such as anemia. Tell your doctor if you have multiple sclerosis or any other nerve disorder. Make sure your doctor knows if you also have a history of hepatitis B infection, tuberculosis, or if you have been in contact with someone who has tuberculosis. You will need to have a skin test for tuberculosis before you start using this medicine. Tell your doctor if you or anyone in your home has ever had a positive reaction to a tuberculosis test. You may get infections more easily while you are using this medicine. Avoid people who are sick or have infections. Call your doctor right away if you develop an infection while using this medicine, or if you have been exposed to chickenpox or any other virus. If you are receiving the injection at home from a prefilled syringe, do not handle the needle cover if you are allergic to latex. The needle cover of the syringe contains latex. Using this medicine may increase your risk of certain types of cancer. Talk with your doctor about this risk. Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or medical tests.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.