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This medication is used to prevent pregnancy. Medroxyprogesterone is like a natural hormone made by the body called progesterone. It works by preventing the growth and release of a mature egg (ovulation), and changing the womb to make it more difficult for an egg to meet sperm (fertilization) or for the fertilized egg to attach to the wall of the womb (implantation).
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Depo-Provera Contraceptive IM images:
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| Overview |
Photos |
How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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Depo-Provera Contraceptive IM
Uses
This medication is used to prevent pregnancy. Medroxyprogesterone is like a natural hormone made by the body called progesterone. It works by preventing the growth and release of a mature egg (ovulation), and changing the womb to make it more difficult for an egg to meet sperm (fertilization) or for the fertilized egg to attach to the wall of the womb (implantation).
Notes
- Do not share this medication with others.Laboratory and/or medical tests (e.g., bone density) should be performed periodically to monitor your progress or check for side effects.
- Consult your doctor for more details.Keep all appointments with your doctor and the laboratory.
- You should have regular complete physical exams including blood pressure, breast exam, pelvic exam, and screening for cervical cancer (Pap smear).
- Your doctor may also order bone density exams if you are using this long term.
- Follow your doctor's instructions for examining your own breasts, and report any lumps immediately.
- Consult your doctor for more details.
Storage
- Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture.
- Do not store in the bathroom.
- Keep all medicines away from children and pets.
How To Use
- Read the Patient Information Leaflet provided by your pharmacist before you start using this product and each time you get a refill.
- The leaflet contains very important information.
- If you have any questions, consult your doctor or pharmacist.Shake the container well before each injection.
- This medication is given by injection into a muscle (upper arm or buttock) by a health care professional once every 3 months (13 weeks).
- The first injection should be given during the first 5 days of your menstrual period to make sure you are not pregnant.If you have recently given birth, the first injection should be given within 5 days after delivery if you are not breast-feeding and during the sixth week after delivery if you are breast-feeding.
- Talk with your doctor about the best time to schedule your first injection.It is very important that you have an injection every 3 months.
- If more than 13 weeks pass between injections, you may become pregnant.
- You may need a pregnancy test to make sure you are not pregnant before getting another injection.
- Other birth control methods (e.g., contraceptive sponge, diaphragm, condom) must be used to protect you from getting pregnant until you can get the next injection.
Side Effects
- Nausea, stomach cramping/bloating, dizziness, headache, tiredness, breast tenderness, decrease in breast size, acne, hair loss, or irritation/pain at injection site may occur.
- If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
- Your periods may be early or late, shorter or longer, or heavier or lighter than normal.
- You may also have some spotting between periods, especially during the first several months of use.
- Your periods may stop completely after you have been receiving this medication for about a year.
- If this occurs, your periods will normally return after you stop receiving this medication.
- If you miss a period and have missed an injection, or if more than 13 weeks pass between injections and you think you may be pregnant, see your doctor.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
- Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes (e.g., depression), changes in sexual interest/ability, swelling of the ankles/feet, unusual/sudden weight gain.Tell your doctor immediately if any of these rare but very serious side effects occur: bone pain, unusual breast discharge/lumps in breast, abnormal severe/persistent vaginal bleeding, persistent nausea/vomiting, seizures, severe stomach/abdominal/pelvic pain, unusual weakness/tiredness, dark urine, yellowing skin/eyes.This drug may rarely cause blood clots.
- Seek immediate medical attention if you notice any of the following rare but very serious side effects: chest/jaw/left arm pain, sudden shortness of breath, confusion, coughing up blood, sudden dizziness/fainting, pain/swelling/warmth in the groin/calf, tingling/weakness/numbness in the arms/legs, sudden/severe headache, slurred speech, vision changes/problems, weakness on one side of the body.A very serious allergic reaction to this drug is rare.
- However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Before using medroxyprogesterone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.This medication should not be used if you have any of the following conditions: history of stroke or other blood clots (e.g., in the legs, eyes, lungs), breast cancer, liver disease, current/suspected pregnancy, abnormal/unexplained vaginal bleeding.Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma, abnormal breast exam, family history of breast cancer, cancer of the reproductive organs (e.g., cervix, uterus), frequent use of alcohol/tobacco, depression, diabetes, eating disorder (anorexia), heart disease (e.g., chest pain, heart failure), high blood pressure, kidney disease, high cholesterol, irregular/missed/light menstrual periods, migraine, personal/family history of bone disease (e.g., osteoporosis), seizures.Before having surgery, including dental surgery, tell your doctor or dentist that you are using this medication.This medication must not be used during pregnancy.
- If you become pregnant or think you may be pregnant, tell your doctor immediately.
- It may take longer for you to get pregnant after you stop using this medication.
- Consult your doctor for more information.This drug passes into breast milk.
- Consult your doctor before breast-feeding.
Missed Dose
- It is important to take each dose as scheduled.
- If you miss a dose, contact your doctor to establish a new dosing schedule.
Drug Interactions
- Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
- Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.This drug should not be used with the following medications because very serious interactions may occur: amprenavir, sodium tetradecyl sulfate.If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting medroxyprogesterone.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: acitretin, aminoglutethimide, anticonvulsants (e.g., phenytoin), corticosteroids (e.g., hydrocortisone, prednisone), isotretinoin, troleandomycin, warfarin.Certain drugs can decrease the effectiveness of birth control by decreasing the amount of birth control hormones in your system.
- This can result in pregnancy.
- These drugs include: aprepitant, bexarotene, bosentan, dapsone, felbamate, griseofulvin, certain HIV protease inhibitors (e.g., indinavir, nelfinavir, ritonavir, zidovudine), modafinil, phenylbutazone, rifamycins (e.g., rifampin), many seizure medications (e.g., barbiturates, carbamazepine, topiramate), St.
- John's wort.
- Consult your doctor or pharmacist for details, and ask if you should use additional reliable birth control methods while taking any of the drugs listed above.This medication may interfere with certain laboratory tests (including certain hormone levels, thyroid tests), possibly causing false test results.
- Make sure laboratory personnel and all your doctors know you are using this medication.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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