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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

DepoCyt IT Uses Cytarabine liposome is a long-acting (sustained-release) chemotherapy drug used to treat cancer in the area around the spinal cord (lymphomatous meningitis). It works by slowing or stopping the growth of cancer cells. Notes Laboratory and/or medical tests (e.g., complete blood count) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. Storage Refrigerate the medication vial between 36-46 degrees F (2-8 degrees C). Do not freeze. Warm the medication to room temperature before preparing the dose. Swirl gently to mix. Do not shake. Prepare this drug immediately before use if possible. Do not prepare this drug more than 4 hours before use. Discard any unused portion of the vial. How To Use This medication is given by injection into the spinal fluid over 1 to 5 minutes by your doctor. It is usually given every 14 days or as directed. Health care professionals must follow all instructions for proper mixing and use of this drug. If you have questions about using this medication properly, consult your pharmacist.After receiving this medication, you will be instructed to lie flat for 1 hour.The dosage and length of treatment depends on your medical condition and response to treatment. After several months, your doctor may only give this drug every 28 days (maintenance dose).To reduce the risk of serious side effects, your doctor will give you other medication(s) such as dexamethasone before and for several days following your treatment. It is very important that you use this medication as directed. Tell you doctor immediately if you cannot take the dexamethasone (e.g., because of vomiting), if you vomit just after taking dexamethasone, or if you miss a dose. Side Effects Nausea, vomiting, or fever may occur. If any of these effects persist or worsen, tell your doctor promptly.Many people using this medication have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects.Tell your doctor immediately if any of these serious side effects occur: headache, tingling/numbness, muscle pain, back pain, neck pain/stiffness, seizures, swelling.Tell your doctor immediately if any of these unlikely but very serious side effects occur: loss of bladder/bowel control, unusual weakness/tiredness, easy bruising/bleeding, signs of infection (e.g., persistent sore throat), mental/mood changes (e.g., confusion), weakness/loss of movement on one side of the body, vision/hearing changes.A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist. Precautions Before using cytarabine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: brain infection (e.g., bacterial/fungal/viral meningitis).Before using this medication, tell your doctor or pharmacist your medical history, especially of: previous chemotherapy, previous radiation therapy.Do not have immunizations/vaccinations without the consent of your doctor, and avoid contact with people who have recently received oral polio vaccine or flu vaccine inhaled through the nose.Wash your hands well to prevent the spread of infections. Avoid contact with people who have illnesses that may spread to others (e.g., flu, chickenpox).To lower your chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports.This drug is not recommended for use during pregnancy. It may harm the unborn baby. If you become pregnant or think you may be pregnant, tell your doctor immediately.It is not known whether this medication passes into breast milk. However, it may have undesirable effects on a nursing infant. Therefore, breast-feeding while using this medication is not recommended. Consult your doctor before breast-feeding. Missed Dose If you miss a dose or your dosing schedule is interrupted, contact your doctor promptly to establish a new dosing schedule. Drug Interactions Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: digoxin, other cancer chemotherapy drugs.This product can affect the results of certain lab tests (e.g., white blood cell counts in CSF), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.