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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Darunavir Prezista Uses Treats human immunodeficiency virus (HIV) infection. HIV causes acquired immune deficiency syndrome (AIDS). Darunavir does not cure HIV or AIDS. It will be used with another drug called Ritonavir (Norvir®) to slow the progress of the disease. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed. Keep all medicine away from children and never share your medicine with anyone. How To Use APPEARANCE: Tablet. Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to. This medicine should always be taken together with ritonavir (Norvir®). It is best to take this medicine with food or milk. Swallow the tablet whole. Do not crush, break, or chew it. Side Effects Call your doctor right away if you notice any of these side effects: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. Blistering, peeling, or red skin rash. Change in how much or how often you urinate. Chest pain or fast heartbeat. Confusion, weakness, and muscle twitching. Excessive hunger or thirst. Fever, chills, cough, sore throat, runny or stuffy nose, and body aches. Numbness or weakness in your arm or leg, or on one side of your body. Numbness, tingling, or burning pain in your hands, arms, legs, or feet. Rapid weight gain. Sudden or severe headache, problems with vision, speech, or walking. Swelling in your hands, ankles, or feet. Trouble breathing. Unusual bleeding or bruising. Precautions You should not use this medicine if you have had an allergic reaction to darunavir. Do not use this medicine if you are also using astemizole (Hismanal®), terfenadine (Seldane®), cisapride (Propulsid®), pimozide (Orap®), midazolam (Versed®), triazolam (Halcion®), or ergot medicines (such as Cafergot®, D.H.E. 45®, Ergomar®, Ergostat®, Migranal®, Wigraine®). Missed Dose If you miss a dose or forget to use your medicine by more than 6 hours, wait and take your next dose at the normal time. If you miss a dose or forget to use your medicine by less than 6 hours, take it as soon as you can. Then take your next dose at the normal time. Do not use extra medicine to make up for a missed dose. Drug Interactions Make sure your doctor knows if you are pregnant, or if you have diabetes, liver disease, or a bleeding disorder known as hemophilia. Tell your doctor if you are allergic to sulfa medicines (such as Bactrim® or Septra®). You should not breast feed if you have HIV or AIDS, because you may give the infection to your baby through your breast milk. When you start taking HIV medicines, your immune system may get stronger. If you have infections that are hidden in your body, such as pneumonia or tuberculosis, you may notice new symptoms when your body tries to fight them. If this occurs, be sure to tell your doctor. This medicine will not keep you from giving HIV to your partner during sex. Make sure you understand and practice safe sex, even if your partner also has HIV. Do not share needles with anyone. Birth control pills may not work as well while you are using darunavir. To keep from getting pregnant, use an additional form of birth control with your pills. Other forms include condoms, diaphragms, or a contraceptive foam or jelly. Do not stop using this medicine unless your doctor tells you to do so. Your doctor will need to check your progress at regular visits while you are using this medicine. Be sure to keep all appointments.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.