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This medication is used to treat muscle tightness and cramping (spasms) caused by certain nerve disorders such as spinal cord injury, stroke, cerebral palsy, and multiple sclerosis. It works by relaxing the muscles. Dantrolene helps reduce muscle pain and stiffness, improves your ability to move around, and lets you do more of your daily activities.Dantrolene is also used with other treatments to prevent or treat special cases of high fever (malignant hyperthermia) related to anesthesia and surgery.This drug may also be used to treat a certain uncommon condition (neuroleptic malignant syndrome) involving muscle stiffness, fever, and fast heartbeat caused by psychiatric medications.
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| Overview |
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How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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Dantrolene
Uses
This medication is used to treat muscle tightness and cramping (spasms) caused by certain nerve disorders such as spinal cord injury, stroke, cerebral palsy, and multiple sclerosis. It works by relaxing the muscles. Dantrolene helps reduce muscle pain and stiffness, improves your ability to move around, and lets you do more of your daily activities.Dantrolene is also used with other treatments to prevent or treat special cases of high fever (malignant hyperthermia) related to anesthesia and surgery.This drug may also be used to treat a certain uncommon condition (neuroleptic malignant syndrome) involving muscle stiffness, fever, and fast heartbeat caused by psychiatric medications.
Notes
- Do not share this medication with others.Laboratory and/or medical tests (e.g., liver function tests) should be performed periodically to check for side effects.
- Consult your doctor for more details.
Storage
- Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light, moisture, and heat.
- Do not store in the bathroom.
- Keep all medicines away from children and pets.
Overdose
- Symptoms of overdose may include: severe muscle weakness, severe tiredness, severe drowsiness.
How To Use
- See also Warning section.Take this medication by mouth as directed by your doctor.
- For the treatment of long-term muscle tightness/spasms, your doctor may slowly increase your dose to lower your chance of side effects until the right dose for you is determined.
- The manufacturer recommends that you do not take more than 400 milligrams per day.Dosage is based on your medical condition, response to therapy, and in some cases weight.
- For the prevention and treatment of malignant hyperthermia, treatment lasts for several days.Take this medication regularly to get the most benefit from it.
- To help you remember, take it at the same times each day.
Side Effects
- See also Warning section.Drowsiness, dizziness, weakness, tiredness, nausea, and diarrhea may occur as your body adjusts to this medication and usually lessen after several days.
- Headache, constipation, slurred speech, and drooling may also occur.
- If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
- Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: sunburn (sun sensitivity), vision changes, black/tarry stools, vomit that looks like coffee grounds, mental/mood changes, trouble swallowing, problems with urination, severe/persistent constipation, seizures, fast heartbeat.Tell your doctor immediately if any of these rare but very serious side effects occur: easy bruising/bleeding, signs of infection (e.g., fever, chills, persistent sore throat), chest pain, swelling of the ankles/feet, trouble breathing.A very serious allergic reaction to this drug is rare.
- However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Before taking dantrolene, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.This medication should not be used if you have certain medical conditions.
- Before using this medicine, consult your doctor or pharmacist if you have: liver problems (e.g., hepatitis, cirrhosis).Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (e.g., chronic obstructive pulmonary disease-COPD), heart problems.This drug may make you dizzy or drowsy.
- Use caution while driving, using machinery, or doing any activity that requires alertness.
- Limit alcoholic beverages.This medication may make you more sensitive to the sun.
- Avoid prolonged sun exposure, tanning booths, and sunlamps.
- Use a sunscreen and wear protective clothing when outdoors.Before having surgery, tell your doctor or dentist that you are using this medication.During pregnancy, this medication should be used only when clearly needed.
- Discuss the risks and benefits with your doctor.This drug passes into breast milk and could have undesirable effects on a nursing infant.
- Therefore, breast-feeding is not recommended while using this drug.
- Consult your doctor before breast-feeding.
Missed Dose
- If you miss a dose, take it as soon as you remember.
- If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
- Do not double the dose to catch up.
Drug Interactions
- Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
- Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: estrogen.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), other muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone).Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients.
- Ask your pharmacist about using those products safely.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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