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This medication is used to help prepare your cervix (the lower opening of the womb) for labor and delivery. It is used in women who are having a normal pregnancy and who are at or near their delivery due date. Dinoprostone is a natural substance that your body makes in preparation for labor. It relaxes and softens your cervix (cervical ripening) to allow the baby to pass through the birth canal during delivery.
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| Overview |
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How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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Cervidil Vagl
Uses
This medication is used to help prepare your cervix (the lower opening of the womb) for labor and delivery. It is used in women who are having a normal pregnancy and who are at or near their delivery due date. Dinoprostone is a natural substance that your body makes in preparation for labor. It relaxes and softens your cervix (cervical ripening) to allow the baby to pass through the birth canal during delivery.
Notes
- Use under direct medical supervision.
Storage
- Store in a freezer between -4 and 14 degrees F (-20 to -10 degrees C) away from light and moisture.
How To Use
- This drug is inserted high in your vagina next to the cervix by your doctor or midwife.
- You will be lying down while the medication is placed, and you will usually need to continue lying down for 2 hours after insertion.
- Your doctor or midwife will tell you when you can get up and walk around.This medication should only be used in a hospital setting with trained medical care available.
- You will be monitored for changes in your cervix, for signs of active labor (e.g., water breaking, strong sustained contractions), and for your baby's condition.
- Your doctor or midwife will remove the insert if there are side effects, after 12 hours, or when it is no longer needed.
- The drug's effects wear off quickly after the insert is removed.
Side Effects
- Side effects such as fever, nausea, vomiting, diarrhea or abdominal pain are uncommon and usually mild.
- If these persist or worsen, notify your doctor or midwife immediately.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects.
- Many people using this medication do not have serious side effects.Tell your doctor immediately if this uncommon but serious side effect occurs: strong contractions that are very close together (uterine overstimulation).This drug has rarely caused injury to the womb (uterine rupture which may require emergency surgery.
- Symptoms include severe pain in your womb and an abnormal heart rate in your baby.
- Your doctor or midwife will be monitoring for this and for signs of uterine overstimulation.A very serious allergic reaction to this drug is unlikely, but immediate medical attention is required if it occurs.
- Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Before using dinoprostone, tell your doctor, midwife, or pharmacist if you are allergic to it; or if you have any other allergies.Before using this drug, tell your doctor your medical history, including: asthma, full term births including previous cesarean section (c-section) births, glaucoma, infections in the vaginal area (e.g., genital herpes), surgery on the cervix, surgery on the womb (uterus), vaginal bleeding during pregnancy, womb scarring.This drug should not be used if you are carrying more than one baby, if your labor has already started, or if your water has broken.This medication should be used only when clearly needed during pregnancy.
- Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk.
- Consult your doctor before breast-feeding.
Missed Dose
Drug Interactions
- Your healthcare professionals (e.g., doctor, midwife, or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it.
- Do not start, stop or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: other prostaglandins (e.g., misoprostol), oxytocin.If you are currently using any of these medications listed above, tell your doctor or pharmacist before you receive dinoprostone.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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