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This medication is used to treat mild to moderate symptoms of a bowel condition called Crohn's disease. While budesonide does not cure this condition, it may help relieve symptoms such as abdominal pain and soft/liquid stools and may decrease the need for anti-diarrhea medications. Budesonide is a corticosteroid that works by decreasing swelling (inflammation).
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| Overview |
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How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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Budesonide
Uses
This medication is used to treat mild to moderate symptoms of a bowel condition called Crohn's disease. While budesonide does not cure this condition, it may help relieve symptoms such as abdominal pain and soft/liquid stools and may decrease the need for anti-diarrhea medications. Budesonide is a corticosteroid that works by decreasing swelling (inflammation).
Notes
- Do not share this medication with others.Laboratory and/or medical tests (e.g., morning cortisol levels) may be performed periodically to monitor your progress or check for side effects.
- Consult your doctor for more details.Lifestyle changes that may help reduce the risk of bone loss (osteoporosis) during long-term therapy include weight-bearing exercise, getting enough calcium and vitamin D, stopping smoking, and limiting alcohol.
- Ask your doctor about lifestyle changes that may benefit you.
Storage
- Store at 77 degrees F (25 degrees C) away from light and moisture.
- Brief storage between 59-86 degrees F (15-30 degrees C) is permitted.
- Do not store in the bathroom.
- Keep all medicines away from children and pets.
How To Use
- Read the Patient Information Leaflet provided by your pharmacist before you start using budesonide and each time you get a refill.
- If you have any questions, consult your doctor or pharmacist.Take this medication by mouth with or without food, usually once daily in the morning or as directed by your doctor.
- Swallow the capsules whole.
- Do not crush or chew the capsules.
- Doing so can destroy the long action of the drug and may increase side effects.The dosage and length of treatment are based on your medical condition and response to therapy.Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise.
- Grapefruit may increase the amount of certain medications in your body.
- Consult your doctor or pharmacist for more details.Use this medication regularly and exactly as prescribed in order to get the most benefit from it.
- To help you remember, use it at the same time each day.
- Do not increase your dose, take it more frequently, or use it for a longer time than prescribed because this may increase your risk of serious side effects.Do not stop taking this medication without consulting your doctor.
- Some conditions may become worse when the drug is suddenly stopped.
- Your dose may need to be gradually decreased to prevent symptoms such as extreme tiredness, weakness, or nausea.
- Follow your doctor's instructions carefully.
- Tell your doctor immediately if you experience any of these symptoms when stopping this medication.Inform your doctor if your condition persists or worsens.
Side Effects
- See also the Precautions section.Headache, nausea, stomach upset, or dizziness may occur.
- If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects.
- Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: signs of infection (e.g., fever, persistent cough, persistent sore throat, frequent/painful urination), mental/mood changes (e.g., depression, mood swings, agitation, confusion), chest pain, shortness of breath, severe dizziness, fast/pounding/irregular heartbeat, headache, tingling of the hands/feet, shaking (tremor), seizures, muscle/joint cramps or pain, severe stomach/abdominal pain, easy bruising/bleeding, puffy face, unusual facial hair growth, increased thirst/urination, increased sweating, swelling of the ankles/feet, slow wound healing, thinning skin, menstrual period changes, unexpected weight gain, unusual tiredness, vision changes, black stools, vomit that looks like coffee grounds, unusual skin growths.Tell your doctor immediately if any of these rare but very serious side effects occur: vision loss, persistent/severe headaches, speech problems, loss of coordination.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.
- Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Before taking budesonide, tell your doctor if you are allergic to it; or to other corticosteroids (e.g., prednisone); or if you have any other allergies.Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, certain eye problems (cataracts, herpes infection, glaucoma), high blood pressure (hypertension), a certain heart problem (congestive heart failure), severe liver disease (cirrhosis), kidney disease, stomach/intestinal problems (e.g., diverticulitis, ulcer, ulcerative colitis), brittle bones (osteoporosis), infections (e.g., tuberculosis, threadworm), bleeding problems, history of blood clots, certain mental/mood conditions (e.g., depression, mood swings), underactive thyroid (hypothyroidism), untreated mineral imbalances (e.g., low potassium/calcium).If you have been using other, stronger corticosteroids (e.g., prednisone) and switch to this medication, or if you have been on this medication for a long time, your body may not be able to make enough natural steroids while you are under stress due to infection, surgery or injury.
- Deaths have sometimes occurred during such stresses due to low steroid levels.
- Tell your doctor immediately if any of the following side effects occur: unusual weakness, nausea/vomiting, stomach/abdominal pain.Consult your doctor or pharmacist for more details and inform them that you use (or have used) any type of corticosteroid.
- Consult your doctor or pharmacist now for advice about future stress situations.
- You may need to carry a supply of corticosteroid tablets as a precaution.
- Carry a warning card or medical ID bracelet that identifies your need for oral corticosteroids during times of stress as noted.
- (See Medical Alert section.) Before having surgery, tell your doctor or dentist that you are taking this medication or that you have taken it within the last 12 months.This medication may mask signs of infection or put you at greater risk of developing very serious infections.
- Report any injuries or signs of infection (e.g., persistent sore throat/cough/fever, pain during urination, muscle aches, changes in sputum color) that occur during treatment.Avoid contact with people who have chickenpox or measles unless you have previously had these diseases (e.g., in childhood).
- If you are exposed to one of these infections and you have not previously had it, seek immediate medical attention.If you have diabetes, this drug may increase your blood sugar levels.
- Check your blood sugar levels regularly as directed by your doctor.
- Tell your doctor immediately if you have symptoms of high blood sugar such as increased thirst/urination.
- Your anti-diabetic medication or diet may need to be adjusted.If you have a history of ulcers or take large doses of aspirin or other arthritis medication, limit alcoholic beverages while taking this drug to decrease the risk of stomach/intestinal bleeding.This drug may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery.
- Limit alcoholic beverages.When used for extended periods, corticosteroids like budesonide may affect bone strength, especially in people who smoke, have a family history of brittle bones (osteoporosis), or take other medications that may weaken bones (e.g., phenytoin).
- Bone density tests may help to determine if you need medication to treat or prevent this problem.
- Discuss with your doctor.Caution is advised when using this drug in children.
- It may slow down a child's growth rate if given for long periods.
- Monitor your child's height and growth rate regularly.
- Consult your doctor for more details.This medication should be used only when clearly needed during pregnancy.
- Rarely, there have been reports of similar drugs causing harm to unborn babies.
- Discuss the risks and benefits with your doctor.
- Infants born to mothers who have been using similar medications for an extended time may have low levels of corticosteroid hormone.
- Tell your doctor immediately if you notice symptoms such as persistent nausea/vomiting, severe diarrhea, or weakness in your newborn.It is not known if this medication passes into breast milk.
- Based on information for similar drugs, this medication may pass into breast milk.
- Breast-feeding while using this drug is not recommended.
- Consult your doctor before breast-feeding.
Missed Dose
- If you miss a dose, take it as soon as you remember.
- If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule.
- Do not double the dose to catch up.
Drug Interactions
- See also the How to Use section.Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it.
- Do not start, stop or change the dosage of any medicine before checking with them first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: drugs affecting liver enzymes that remove budesonide from your body (azole antifungals including ketoconazole and itraconazole, barbiturates including phenobarbital, cimetidine, HIV protease inhibitors including ritonavir, macrolide antibiotics including erythromycin, rifamycins including rifabutin, St.
- Johns wort, certain anti-seizure medicines including carbamazepine), nonsteroidal anti-inflammatory drugs (NSAIDS such as ibuprofen, naproxen), drugs for diabetes (e.g., glyburide, insulin), quinolone antibiotics (e.g., ciprofloxacin, levofloxacin), drugs that affect the immune system (e.g., cyclosporine), bupropion, aldesleukin, mifepristone, licorice (glycyrrhiza).This product may interfere with certain lab tests.
- Make sure laboratory personnel and all your doctors know you use this drug.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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