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Drug Guide    B   Bortezomib

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   Bortezomib

Bortezomib
(injection) (injectable)


Treats multiple myeloma (blood plasma cell cancer) and mantle cell lymphoma (lymph node cancer).

ALTERNATE NAMES

Velcade

 
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  Bortezomib images:

Overview Photos How To Use Side Effects Precautions Missed Dose Drug Interactions

Bortezomib
Velcade
Uses
Treats multiple myeloma (blood plasma cell cancer) and mantle cell lymphoma (lymph node cancer).



How To Use
  • APPEARANCE: Injectable. Medicines used to treat cancer are very strong and can have many side effects.
  • Before receiving this medicine, make sure you understand all the risks and benefits.
  • It is important for you to work closely with your doctor during your treatment. Your doctor will prescribe your exact dose and tell you how often it should be given.
  • This medicine is given through a needle placed in one of your veins. You will receive this medicine while you are in a hospital or cancer treatment center.
  • A nurse or other trained health professional will give you this medicine. You may also receive medicines to help prevent nausea, vomiting, or diarrhea.
  • Ask your doctor or other health caregiver if you should drink extra water while you are using this medicine.
  • This could help you avoid feeling dizzy or lightheaded.

Side Effects
  • Call your doctor right away if you notice any of these side effects: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. Blistering, peeling, red skin rash. Change in how much and how often you urinate, or painful urination. Confusion, weakness, and muscle twitching. Dry mouth, increased thirst, or muscle cramps. Fast, slow, or irregular heartbeat. Fever, chills, cough, runny or stuffy nose, sore throat, and body aches. Lightheadedness, dizziness, drowsiness, or fainting. Numbness or weakness in your arm or leg, or on one side of your body. Numbness, tingling, or burning pain in your hands, arms, legs, or feet. Pain in your lower leg (calf). Red or dark brown urine. Seizures, tremors, or stiff neck. Severe diarrhea, nausea, and vomiting. Shortness of breath, chest pain, cold sweats, coughing up blood, or bluish-colored skin. Sudden or severe headache, problems with vision, speech, or walking. Sudden or severe stomach pain and tenderness, red or black stools, or rectal bleeding. Swelling in your face, arms, legs, ankles, or feet. Trouble swallowing. Unusual bleeding or bruising. Vomiting of blood or coffee-ground materials. Yellowing of your skin or the whites of your eyes.

Precautions
  • You should not receive this medicine if you have had an allergic reaction to bortezomib, boron, or mannitol, or if you are pregnant.

Missed Dose
  • This medicine needs to be given on a fixed schedule.
  • If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Drug Interactions
  • Using this medicine while you are pregnant can harm your unborn baby.
  • Use an effective form of birth control to keep from getting pregnant.
  • If you think you have become pregnant while using the medicine, tell your doctor right away. Do not breast feed while you are using this medicine. Make sure your doctor knows if you have heart disease, liver disease, lung disease, kidney disease, diabetes, a history of fainting or low blood pressure, or have ever had a nerve problem called peripheral neuropathy. This medicine may make you dizzy or drowsy.
  • Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
  • You may feel lightheaded when standing, so stand up slowly. This medicine lowers the number of some types of blood cells in your body.
  • Because of this, you may bleed or get infections more easily.
  • To help with these problems, avoid being near people who are sick or have infections.
  • Wash your hands often.
  • Stay away from rough sports or other situations where you could be bruised, cut, or injured.
  • Brush and floss your teeth gently.
  • Be careful when using sharp objects, including razors and fingernail clippers. Your doctor will need to check your blood at regular visits while you are using this medicine.
  • Be sure to keep all appointments. Cancer medicines can cause nausea and/or vomiting in most people, sometimes even after receiving medicines to prevent it.
  • Ask your doctor or nurse about other ways to control these side effects.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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