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This medication is a cancer chemotherapy drug used to treat certain types of tumors (e.g., multiple myeloma). It blocks certain proteins which helps to slow the growth and spread of the cancer.
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| Overview |
Photos |
How To Use |
Side Effects |
Precautions |
Missed Dose |
Drug Interactions |
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Bortezomib
Uses
This medication is a cancer chemotherapy drug used to treat certain types of tumors (e.g., multiple myeloma). It blocks certain proteins which helps to slow the growth and spread of the cancer.
Notes
- Do not share this medication with others.Laboratory and/or medical tests (e.g., complete blood counts, platelets) should be performed periodically to monitor your progress or check for side effects.
- Consult your doctor for more details.
Storage
- Store unopened vials at room temperature (77 degrees F or 25 degrees C).
- Store vials in original package to protect from light.
- Brief storage between 59 to 86 degrees F (15-30 degrees C) is permitted.
- Once mixed, use the solution within 8 hours.
- Do not store in the bathroom.
- Keep all medicines away from children and pets.
Overdose
- Symptoms of overdose may include: fainting or persistent fever.
How To Use
- This medication is given by injection into a vein (IV) by a healthcare professional.
- The dosage is based on your medical condition and response to therapy.
- Follow all directions for proper mixing.
- Before using, check this medication visually for particles or discoloration.
- If either is present, do not use the liquid.
- If you have questions regarding the use of this medication, consult the pharmacist.It is important to drink plenty of fluids while you are being treated with this drug to prevent becoming dehydrated.
- Read the Patient Information Leaflet that comes with this drug, and consult your doctor or pharmacist if you have any questions.
Side Effects
- Dizziness, lightheadedness, nausea, vomiting, loss of appetite, diarrhea, constipation, tiredness, weakness, or blurred vision may occur.
- If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects.
- Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these serious side effects occur: easy bruising or bleeding, tingling/numbness/pain/burning feeling of the hands or feet (peripheral neuropathy), fainting.This medication can lower your body's ability to fight an infection.
- Notify your doctor promptly if you develop any signs of an infection such as fever, chills, or persistent sore throat.Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: stomach pain, black stools, coffee-ground vomit, trouble breathing, swelling or pain in the lower legs, fast/irregular heartbeat, severe headache, chest pain, one-sided weakness, vision problems, slurred speech, mental/mood changes (e.g., rarely, thoughts of suicide), seizures, swelling of the hands/ankles/feet, change in the amount of urine, yellowing skin/eyes, dark urine.An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs.
- Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist.
Precautions
- Before using this medication, tell your doctor or pharmacist your medical history, especially of: nerve sensation problems (e.g., peripheral neuropathy), heart disease, low blood pressure, loss of body fluids (dehydration), diabetes, liver disease, severe kidney disease, certain viral infection (herpes, shingles), any allergies (especially to boron or mannitol).To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position.This drug may make you dizzy or cause vision changes; use caution engaging in activities requiring alertness such as driving or using machinery.
- Limit alcoholic beverages.Do not have immunizations/vaccinations without the consent of your doctor and avoid contact with people who have recently received oral polio vaccine.Use caution with sharp objects like safety razors or nail cutters and avoid activities such as contact sports to lower the chance of getting cut, bruised, or injured.Wash your hands well to prevent the spread of infections.This medication must not be used during pregnancy.
- It may cause harm to an unborn baby.
- If you become pregnant or think you may be pregnant, inform your doctor immediately.
- Use reliable form(s) of birth control during treatment with this drug.
- Consult your doctor for more details.It is not known whether this drug passes into breast milk.
- Breast-feeding is not recommended while using this drug due to the potential risk to the nursing infant.
- Consult your doctor before breast-feeding.
Missed Dose
- It is important to use each dose at the scheduled time.
- If you miss a dose, contact your doctor to establish a new dosing schedule.
- Do not "double-up" the dose to catch up.
Drug Interactions
- Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.
- Do not start, stop, or change the dosage of any medicine before checking with them first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of: medications to treat high blood pressure, oral anti-diabetic drugs, other drugs that may cause peripheral neuropathy (e.g., amiodarone, isoniazid, nitrofurantoin, certain anti-virals such as acyclovir, ritonavir, zidovudine).
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
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