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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Biaxin XL Pak Uses This medication is used to treat a wide variety of bacterial respiratory tract infections. Clarithromycin is a macrolide antibiotic that works by stopping the growth of bacteria.This antibiotic treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness. Notes Do not share this medication with others.This medication has been prescribed for your current condition only. Do not use it later for another infection unless told to do so by your doctor. A different medication may be necessary in those cases.Laboratory and/or medical tests (e.g., blood counts, cultures, liver or kidney function tests) may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details. Storage Store the US product at room temperature between 68-77 degrees F (20-25 degrees C). Brief storage between 59-86 degrees F (15-30 degrees C) is permitted.Store the Canadian product at room temperature between 59-77 degrees F (15-25 degrees C). Protect from light.Do not store in the bathroom. Keep all medicines away from children and pets. How To Use Take this medication by mouth with food, usually once daily, or as directed by your doctor. Swallow the tablet whole. Do not crush or chew the tablet.Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this medication at the same time each day.The dosage and duration of therapy is based on your medical condition and response to therapy.Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection.Inform your doctor if your condition persists or worsens. Side Effects Diarrhea, nausea, vomiting, stomach upset, changes in taste, and headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.A tablet may rarely appear in your stool. This is more likely to occur if you have certain intestinal disorders (e.g., ileostomy, colostomy, diarrhea). Contact your doctor or pharmacist for further instructions.Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor immediately if any of these unlikely but serious side effects occur: hearing loss, mental/mood changes.Tell your doctor immediately if any of these rare but very serious side effects occur: fainting, fast/irregular heartbeats, new signs of infection (e.g., fever, persistent sore throat), persistent nausea/vomiting, severe stomach/abdominal pain, dark urine, yellowing of eyes or skin, change in the amount of urine.This medication may rarely cause a severe intestinal condition (pseudomembranous colitis) due to resistant bacteria. This condition may occur while receiving therapy or even weeks after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool.Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing.If you notice other effects not listed above, contact your doctor or pharmacist. Precautions Before taking clarithromycin, tell your doctor or pharmacist if you are allergic to it; or to other macrolide antibiotics (e.g., erythromycin, azithromycin); or if you have any other allergies.This medication should be used with caution if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: liver or kidney disease, certain heart problems (e.g., QTc prolongation, bradycardia), mineral imbalance (e.g., low potassium or magnesium levels), family history of certain heart rhythm disorders (QTc prolongation).This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.Based on information for similar drugs, this medication may pass into breast milk. Therefore, consult your doctor before breast-feeding. Missed Dose If you miss a dose, take it as soon as you remember. If it is near the time of your next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up. Drug Interactions Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.This drug should not be used with the following medications because very serious interactions may occur: eletriptan, eplerenone, ergot alkaloids (e.g., ergotamine, dihydroergotamine), ivabradine, quinupristin-dalfopristin, ranolazine, drugs which may affect the heart rhythm (cisapride, pimozide).If you are currently using any of these medications, tell your doctor or pharmacist before starting clarithromycin.Other drugs besides clarithromycin and those listed above which may affect the heart rhythm (QTc prolongation) include amiodarone, dofetilide, quinidine, sotalol, moxifloxacin, gatifloxacin, propafenone, thioridazine among others. QTc prolongation can infrequently result in serious, rarely fatal, irregular heartbeats. Consult your doctor or pharmacist for more details, and for instructions on how you may minimize the risk of this effect.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: drugs affecting liver enzymes that remove clarithromycin from your body (such as rifamycins - including rifabutin and rifampin, and azole antifungals - including itraconazole and fluconazole), certain HIV medications (e.g., zidovudine, delavirdine, protease inhibitors such as atazanavir, ritonavir), certain anti-seizure medications (e.g., carbamazepine, phenytoin, valproate), "blood thinners" (e.g., warfarin), colchicine, digoxin, live bacterial vaccines.This drug can slow down the removal of other drugs from your body by affecting certain liver enzymes. Some examples of these affected drugs include alfentanil, certain benzodiazepines (e.g., alprazolam, midazolam, triazolam), bromocriptine, cilostazol, corticosteroids (e.g., methylprednisolone), cyclosporine, disopyramide, repaglinide, sildenafil, certain statins (atorvastatin, lovastatin, simvastatin), tacrolimus, tolterodine, theophylline.This medication may decrease the effectiveness of combination-type birth control pills. This can result in pregnancy. You may need to use an additional form of reliable birth control while using this medication. Consult your doctor or pharmacist for details.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.