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Overview	Photos	How To Use	Side Effects	Precautions	Missed Dose	Drug Interactions

Aprepitant Emend, Emend Tri-Fold Pack Uses Used with other medicines to prevent nausea and vomiting caused by cancer treatment (chemotherapy) or nausea and vomiting occurring after surgery. Storage Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. If your medicine comes in a bottle, you might find a small packet in the bottle with your medicine. Keep this packet inside the bottle with the capsules. It helps keep the capsules from getting damp. Do not eat or swallow this packet. Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed. Keep all medicine away from children and never share your medicine with anyone. How To Use APPEARANCE: Capsule. Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to. This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. You may take this medicine with or without food. This medicine is usually used once a day for 3 days in a row, beginning on the first day of your chemotherapy treatment. Take your first dose 1 hour before your chemotherapy treatment starts. Take your second and third doses each morning for the next 2 days. Your doctor will give you this medicine 3 hours before your surgery starts. You might need to use other medicines at the same time you use aprepitant. Aprepitant is not for long-term use, but you may need to use this three-dose routine again if you have more chemotherapy treatments in the future. Side Effects Call your doctor right away if you notice any of these side effects: Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. Fever, chills, cough, sore throat, and body aches. Lightheadedness, dizziness, or fainting. Nausea, vomiting, diarrhea, constipation, or stomach pain. Precautions You should not use this medicine if you have had an allergic reaction to aprepitant, or if you are also using pimozide (Orap®), terfenadine (Seldane®), astemizole (Hismanal®), or cisapride (Propulsid®). Aprepitant may cause serious or life-threatening problems if used together with these medicines. Missed Dose If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose. Drug Interactions Make sure your doctor knows if you are pregnant, planning to become pregnant, or breastfeeding. If you have liver disease, talk to your doctor before taking this medicine. Do not use this medicine to treat nausea or vomiting that has already started. Your doctor will need to check your blood after using this medicine if you are also taking warfarin (Coumadin®).

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgement of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.